| Item Type | Name |
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Concept
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DNA Damage
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Concept
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DNA-Binding Proteins
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Concept
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DNA Mutational Analysis
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Concept
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DNA, Neoplasm
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Concept
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DNA
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Concept
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DNA Topoisomerases, Type II
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Concept
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DNA-Directed DNA Polymerase
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Concept
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DNA Viruses
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Concept
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DNA, Viral
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Concept
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DNA-Directed RNA Polymerases
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Concept
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Sequence Analysis, DNA
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Concept
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DNA, Complementary
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Concept
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DNA-Activated Protein Kinase
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Concept
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DNA Fragmentation
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Concept
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DNA, Single-Stranded
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Concept
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DNA Primers
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Academic Article
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Redefining virology.
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Academic Article
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Bcl-2 blocks a caspase-dependent pathway of apoptosis activated by herpes simplex virus 1 infection in HEp-2 cells.
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Academic Article
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Molecular targeting of gene therapy and radiotherapy.
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Academic Article
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An early regulatory function required in a cell type-dependent manner is expressed by the genomic but not the cDNA copy of the herpes simplex virus 1 gene encoding infected cell protein 0.
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Academic Article
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E2F proteins are posttranslationally modified concomitantly with a reduction in nuclear binding activity in cells infected with herpes simplex virus 1.
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Academic Article
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RNAs extracted from herpes simplex virus 1 virions: apparent selectivity of viral but not cellular RNAs packaged in virions.
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Academic Article
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The US3 protein kinase of herpes simplex virus 1 mediates the posttranslational modification of BAD and prevents BAD-induced programmed cell death in the absence of other viral proteins.
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Academic Article
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cdc2 cyclin-dependent kinase binds and phosphorylates herpes simplex virus 1 U(L)42 DNA synthesis processivity factor.
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Academic Article
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Dose-dependent and independent temporal patterns of gene responses to ionizing radiation in normal and tumor cells and tumor xenografts.
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Academic Article
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Herpes simplex virus 1 activates cdc2 to recruit topoisomerase II alpha for post-DNA synthesis expression of late genes.
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Academic Article
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Engineered herpes simplex virus 1 is dependent on IL13Ralpha 2 receptor for cell entry and independent of glycoprotein D receptor interaction.
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Academic Article
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Requirements for the nuclear-cytoplasmic translocation of infected-cell protein 0 of herpes simplex virus 1.
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Academic Article
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The herpes simplex virus 1 UL41 gene-dependent destabilization of cellular RNAs is selective and may be sequence-specific.
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Academic Article
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STAT1 is overexpressed in tumors selected for radioresistance and confers protection from radiation in transduced sensitive cells.
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Academic Article
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Herpes simplex virus 1 gene products occlude the interferon signaling pathway at multiple sites.
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Academic Article
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Receiver operating characteristic analysis: a general tool for DNA array data filtration and performance estimation.
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Academic Article
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Herpes simplex virus 1 ICP22 regulates the accumulation of a shorter mRNA and of a truncated US3 protein kinase that exhibits altered functions.
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Academic Article
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The first 30 minutes in the life of a virus: unREST in the nucleus.
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Academic Article
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Ionizing radiation activates late herpes simplex virus 1 promoters via the p38 pathway in tumors treated with oncolytic viruses.
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Academic Article
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Herpes simplex virus 1 induces cytoplasmic accumulation of TIA-1/TIAR and both synthesis and cytoplasmic accumulation of tristetraprolin, two cellular proteins that bind and destabilize AU-rich RNAs.
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Academic Article
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State and role of SRC family kinases in replication of herpes simplex virus 1.
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Academic Article
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Proteolytic cleavage of VP1-2 is required for release of herpes simplex virus 1 DNA into the nucleus.
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Academic Article
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Temperature-sensitive mutations in the putative herpes simplex virus type 1 terminase subunits pUL15 and pUL33 preclude viral DNA cleavage/packaging and interaction with pUL28 at the nonpermissive temperature.
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Academic Article
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Replication-competent herpes simplex virus 1 isolates selected from cells transfected with a bacterial artificial chromosome DNA lacking only the UL49 gene vary with respect to the defect in the UL41 gene encoding host shutoff RNase.
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Academic Article
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An interferon-related gene signature for DNA damage resistance is a predictive marker for chemotherapy and radiation for breast cancer.
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Academic Article
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Cells lacking NF-kappaB or in which NF-kappaB is not activated vary with respect to ability to sustain herpes simplex virus 1 replication and are not susceptible to apoptosis induced by a replication-incompetent mutant virus.
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Academic Article
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Components of the REST/CoREST/histone deacetylase repressor complex are disrupted, modified, and translocated in HSV-1-infected cells.
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Academic Article
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Radioresistance of Stat1 over-expressing tumour cells is associated with suppressed apoptotic response to cytotoxic agents and increased IL6-IL8 signalling.
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Academic Article
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Role of herpes simplex virus ICP27 in the degradation of mRNA by virion host shutoff RNase.
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Academic Article
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Interwoven roles of cyclin D3 and cdk4 recruited by ICP0 and ICP4 in the expression of herpes simplex virus genes.
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Academic Article
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Herpes simplex virus-infected cell protein 0 blocks the silencing of viral DNA by dissociating histone deacetylases from the CoREST-REST complex.
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Academic Article
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The histone acetyltransferase CLOCK is an essential component of the herpes simplex virus 1 transcriptome that includes TFIID, ICP4, ICP27, and ICP22.
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Academic Article
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Molecular pathways: interferon/stat1 pathway: role in the tumor resistance to genotoxic stress and aggressive growth.
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Academic Article
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The two functions of herpes simplex virus 1 ICP0, inhibition of silencing by the CoREST/REST/HDAC complex and degradation of PML, are executed in tandem.
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Academic Article
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Circadian CLOCK histone acetyl transferase localizes at ND10 nuclear bodies and enables herpes simplex virus gene expression.
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Academic Article
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Overexpression of the ubiquitin-specific protease 7 resulting from transfection or mutations in the ICP0 binding site accelerates rather than depresses herpes simplex virus 1 gene expression.
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Academic Article
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During its nuclear phase the multifunctional regulatory protein ICP0 undergoes proteolytic cleavage characteristic of polyproteins.
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Academic Article
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The disappearance of cyclins A and B and the increase in activity of the G(2)/M-phase cellular kinase cdc2 in herpes simplex virus 1-infected cells require expression of the alpha22/U(S)1.5 and U(L)13 viral genes.
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Academic Article
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Identification of a novel expressed open reading frame situated between genes U(L)20 and U(L)21 of the herpes simplex virus 1 genome.
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Academic Article
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Oct-1 is posttranslationally modified and exhibits reduced capacity to bind cognate sites at late times after infection with herpes simplex virus 1.
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Academic Article
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Post-transcriptional processing of cellular RNAs in herpes simplex virus-infected cells.
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Academic Article
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Nuclear retention of ICP0 in cells exposed to HDAC inhibitor or transfected with DNA before infection with herpes simplex virus 1.
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Academic Article
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Engagement of the lysine-specific demethylase/HDAC1/CoREST/REST complex by herpes simplex virus 1.
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Academic Article
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ICP0 enables and monitors the function of D cyclins in herpes simplex virus 1 infected cells.
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Academic Article
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Use of biotinylated plasmid DNA as a surrogate for HSV DNA to identify proteins that repress or activate viral gene expression.
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Academic Article
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Selective degradation of mRNAs by the HSV host shutoff RNase is regulated by the UL47 tegument protein.
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Academic Article
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Interaction of herpes simplex virus ICP0 with ND10 bodies: a sequential process of adhesion, fusion, and retention.
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Academic Article
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Role of activating transcription factor 3 in the synthesis of latency-associated transcript and maintenance of herpes simplex virus 1 in latent state in ganglia.
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Grant
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MOLECULAR BIOLOGY OF HERPES SIMPLEX VIRUSES
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Grant
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FUNCTIONS FOR HERPES SIMPLEX VIRUS ICP22 AND US1.5
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Grant
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The functions of the US3 protein kinase of herpes simplex virus
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Grant
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Dissection of the Functions of Herpes Simplex Virus ICPO
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Grant
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MECHANISMS OF VIRAL INFECTION IN RELATION TO CANCER
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Grant
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CONFERENCE ON CONTROL OF VIRAL LATENCY AND PERSISTENCE
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Grant
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MECHANISMS OF VIRAL INFECTION IN RELATION TO CANCER
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Grant
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HERPES SIMPLEX VIRUS MULTIPLICATION
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