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Roizman, Bernard
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Item TypeName
Concept Transfection
Academic Article Bcl-2 blocks a caspase-dependent pathway of apoptosis activated by herpes simplex virus 1 infection in HEp-2 cells.
Academic Article Of the three tegument proteins that package mRNA in herpes simplex virions, one (VP22) transports the mRNA to uninfected cells for expression prior to viral infection.
Academic Article Engineered herpes simplex virus 1 is dependent on IL13Ralpha 2 receptor for cell entry and independent of glycoprotein D receptor interaction.
Academic Article Herpes simplex virus protein kinase US3 activates and functionally overlaps protein kinase A to block apoptosis.
Academic Article Prevention of restenosis by a herpes simplex virus mutant capable of controlled long-term expression in vascular tissue in vivo.
Academic Article In transduced cells, the US3 protein kinase of herpes simplex virus 1 precludes activation and induction of apoptosis by transfected procaspase 3.
Academic Article Replication-competent herpes simplex virus 1 isolates selected from cells transfected with a bacterial artificial chromosome DNA lacking only the UL49 gene vary with respect to the defect in the UL41 gene encoding host shutoff RNase.
Academic Article Systemic delivery of (gamma1)34.5-deleted herpes simplex virus-1 selectively targets and treats distant human xenograft tumors that express high MEK activity.
Academic Article Interaction of herpes simplex virus RNase with VP16 and VP22 is required for the accumulation of the protein but not for accumulation of mRNA.
Academic Article Circadian CLOCK histone acetyl transferase localizes at ND10 nuclear bodies and enables herpes simplex virus gene expression.
Academic Article Overexpression of the ubiquitin-specific protease 7 resulting from transfection or mutations in the ICP0 binding site accelerates rather than depresses herpes simplex virus 1 gene expression.
Academic Article Identification of a novel expressed open reading frame situated between genes U(L)20 and U(L)21 of the herpes simplex virus 1 genome.
Academic Article Nuclear retention of ICP0 in cells exposed to HDAC inhibitor or transfected with DNA before infection with herpes simplex virus 1.
Academic Article ICP0 enables and monitors the function of D cyclins in herpes simplex virus 1 infected cells.
Academic Article Role of herpes simplex virus ICP0 in the transactivation of genes introduced by infection or transfection: a reappraisal.
Academic Article Selective degradation of mRNAs by the HSV host shutoff RNase is regulated by the UL47 tegument protein.
Grant DISSECTION OF THE FUNCTIONS OF HERPES SIMPLEX VIRUS ICPO
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  • Transfection