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Posner, Mitchell
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Posner, Mitchell
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Concept
Oncolytic Virotherapy
Academic Article
Activated MEK suppresses activation of PKR and enables efficient replication and in vivo oncolysis by Deltagamma(1)34.5 mutants of herpes simplex virus 1.
Academic Article
Tumor genotype determines susceptibility to oncolytic herpes simplex virus mutants: strategies for clinical application.
Academic Article
Systemic delivery of (gamma1)34.5-deleted herpes simplex virus-1 selectively targets and treats distant human xenograft tumors that express high MEK activity.
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Oncolytic Virotherapy