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Larson, Richard A.
One or more keywords matched the following items that are connected to Larson, Richard A.
Item TypeName
Concept Chromosome Banding
Concept Chromosomes, Human, Pair 11
Concept Chromosomes, Human, Pair 2
Concept Chromosomes, Human, Pair 6
Concept Chromosomes, Human, Pair 8
Concept Chromosomes, Human, Pair 1
Concept Chromosomes, Human, Pair 15
Concept Chromosomes, Human, Pair 21
Concept Chromosomes, Human, Pair 3
Concept Chromosomes, Human, Pair 12
Concept Chromosomes, Human, Pair 14
Concept Chromosome Deletion
Concept Chromosome Mapping
Concept Chromosomes, Human, Pair 13
Concept Chromosomes, Human, Pair 22
Concept Chromosomes, Human, Pair 4
Concept Chromosomes, Human, Pair 5
Concept Chromosomes, Human, Pair 7
Concept Chromosomes, Human, Pair 20
Concept Chromosomes, Human, Pair 17
Concept Chromosomes, Human, Pair 9
Concept Chromosome Inversion
Concept Philadelphia Chromosome
Concept Chromosome Disorders
Concept Chromosome Aberrations
Concept Chromosomes, Human, Pair 16
Concept X Chromosome
Concept Chromosome Breakage
Concept Physical Chromosome Mapping
Academic Article Cytogenetic and molecular delineation of the smallest commonly deleted region of chromosome 5 in malignant myeloid diseases.
Academic Article Refractory cytopenia with multilineage dysplasia: further characterization of an 'unclassifiable' myelodysplastic syndrome.
Academic Article Lineage involvement by BCR/ABL in Ph+ lymphoblastic leukemias: chronic myelogenous leukemia presenting in lymphoid blast vs Ph+ acute lymphoblastic leukemia.
Academic Article Clinical, morphologic, and cytogenetic characteristics of 26 patients with acute erythroblastic leukemia.
Academic Article Polymerase chain reaction-based diagnosis of del (5q) in acute myeloid leukemia and myelodysplastic syndrome identifies a minimal deletion interval.
Academic Article Cytogenetic and molecular delineation of a region of chromosome 7 commonly deleted in malignant myeloid diseases.
Academic Article Clinical significance of the BCR-ABL fusion gene in adult acute lymphoblastic leukemia: a Cancer and Leukemia Group B Study (8762).
Academic Article Familial myeloid leukemia associated with loss of the long arm of chromosome 5.
Academic Article Myeloid leukemia after hematotoxins.
Academic Article Clinical and cytogenetic responses to granulocyte-macrophage colony-stimulating factor in therapy-related myelodysplasia.
Academic Article Prospective karyotype analysis in adult acute lymphoblastic leukemia: the cancer and leukemia Group B experience.
Academic Article Balanced translocations involving chromosome bands 11q23 and 21q22 in therapy-related leukemia.
Academic Article Refinement of the smallest commonly deleted segment of chromosome 20 in malignant myeloid diseases and development of a PAC-based physical and transcription map.
Academic Article Molecular delineation of the smallest commonly deleted region of chromosome 5 in malignant myeloid diseases to 1-1.5 Mb and preparation of a PAC-based physical map.
Academic Article Prevalence of the inactivating 609C-->T polymorphism in the NAD(P)H:quinone oxidoreductase (NQO1) gene in patients with primary and therapy-related myeloid leukemia.
Academic Article dic(5;17): a recurring abnormality in malignant myeloid disorders associated with mutations of TP53.
Academic Article CBFA2(AML1) translocations with novel partner chromosomes in myeloid leukemias: association with prior therapy.
Academic Article Detection of trisomy 12 in chronic lymphocytic leukemia by fluorescence in situ hybridization to interphase cells: a simple and sensitive method.
Academic Article Transcript map and comparative analysis of the 1.5-Mb commonly deleted segment of human 5q31 in malignant myeloid diseases with a del(5q).
Academic Article Therapy-related myeloid leukemias are observed in patients with chronic lymphocytic leukemia after treatment with fludarabine and chlorambucil: results of an intergroup study, cancer and leukemia group B 9011.
Academic Article t(1;3)(p36;p21) is a recurring therapy-related translocation.
Academic Article Perspectives on the treatment of chronic phase and advanced phase CML and Philadelphia chromosome positive ALL(1).
Academic Article Acute lymphoblastic leukaemia: diagnosis and classification.
Academic Article Acquired FANCA dysfunction and cytogenetic instability in adult acute myelogenous leukemia.
Academic Article Polymorphisms in the MLL breakpoint cluster region (BCR).
Academic Article Additional cytogenetic abnormalities in adults with Philadelphia chromosome-positive acute lymphoblastic leukaemia: a study of the Cancer and Leukaemia Group B.
Academic Article Abnormal cytogenetics at date of morphologic complete remission predicts short overall and disease-free survival, and higher relapse rate in adult acute myeloid leukemia: results from cancer and leukemia group B study 8461.
Academic Article Adult de novo acute myeloid leukemia with t(6;11)(q27;q23): results from Cancer and Leukemia Group B Study 8461 and review of the literature.
Academic Article Repetitive cycles of high-dose cytarabine benefit patients with acute myeloid leukemia and inv(16)(p13q22) or t(16;16)(p13;q22): results from CALGB 8461.
Academic Article Clinical-cytogenetic associations in 306 patients with therapy-related myelodysplasia and myeloid leukemia: the University of Chicago series.
Academic Article Prognostic factors and outcome of core binding factor acute myeloid leukemia patients with t(8;21) differ from those of patients with inv(16): a Cancer and Leukemia Group B study.
Academic Article A retrospective study of 69 patients with t(6;9)(p23;q34) AML emphasizes the need for a prospective, multicenter initiative for rare 'poor prognosis' myeloid malignancies.
Academic Article Evolving concepts in the management of chronic myeloid leukemia: recommendations from an expert panel on behalf of the European LeukemiaNet.
Academic Article Trisomy 6: a recurring cytogenetic abnormality associated with marrow hypoplasia.
Academic Article Therapy-related myeloid leukaemia: a model for leukemogenesis in humans.
Academic Article Myelodysplasia: when to treat and how.
Academic Article Gene expression profiles in acute myeloid leukemia with common translocations using SAGE.
Academic Article Adverse prognostic significance of KIT mutations in adult acute myeloid leukemia with inv(16) and t(8;21): a Cancer and Leukemia Group B Study.
Academic Article Therapy-related myelodysplastic syndrome: morphologic subclassification may not be clinically relevant.
Academic Article Comprehensive assessment of genetic and molecular features predicting outcome in patients with chronic lymphocytic leukemia: results from the US Intergroup Phase III Trial E2997.
Academic Article Deletions of interferon genes in acute lymphoblastic leukemia.
Academic Article Etiology and management of therapy-related myeloid leukemia.
Academic Article Therapy-related myeloid leukemia.
Academic Article Multiple unrelated clonal abnormalities in host bone marrow cells after allogeneic stem cell transplantation.
Academic Article Clinical, morphologic, and cytogenetic characteristics of patients with lymphoid malignancies characterized by both t(14;18)(q32;q21) and t(8;14)(q24;q32) or t(8;22)(q24;q11).
Academic Article Histone deacetylase inhibitor romidepsin has differential activity in core binding factor acute myeloid leukemia.
Academic Article Prognostic significance of additional cytogenetic abnormalities in newly diagnosed patients with Philadelphia chromosome-positive chronic myelogenous leukemia treated with interferon-alpha: a Cancer and Leukemia Group B study.
Academic Article Interphase cytogenetic analysis detects minimal residual disease in a case of acute lymphoblastic leukemia and resolves the question of origin of relapse after allogeneic bone marrow transplantation.
Academic Article Pretreatment cytogenetics add to other prognostic factors predicting complete remission and long-term outcome in patients 60 years of age or older with acute myeloid leukemia: results from Cancer and Leukemia Group B 8461.
Academic Article The t(2;5)(p23;q35): a recurring chromosomal abnormality in Ki-1-positive anaplastic large cell lymphoma.
Academic Article Acute lymphoblastic leukemia: older patients and newer drugs.
Academic Article Is secondary leukemia an independent poor prognostic factor in acute myeloid leukemia?
Academic Article Morphology in Ki-1(CD30)-positive non-Hodgkin's lymphoma is correlated with clinical features and the presence of a unique chromosomal abnormality, t(2;5)(p23;q35).
Academic Article Clinicopathologic manifestations and breakpoints of the t(3;5) in patients with acute nonlymphocytic leukemia.
Academic Article High dose cytarabine and mitoxantrone: an effective induction regimen for high-risk acute myeloid leukemia (AML).
Academic Article Nilotinib vs imatinib in patients with newly diagnosed Philadelphia chromosome-positive chronic myeloid leukemia in chronic phase: ENESTnd 3-year follow-up.
Academic Article Nilotinib versus imatinib for the treatment of patients with newly diagnosed chronic phase, Philadelphia chromosome-positive, chronic myeloid leukaemia: 24-month minimum follow-up of the phase 3 randomised ENESTnd trial.
Academic Article Associations between morphology, karyotype, and clinical features in myeloid leukemias.
Academic Article Prognostic implications of morphology and karyotype in primary myelodysplastic syndromes.
Academic Article Acute myelomonocytic leukemia with abnormal eosinophils and inv(16) or t(16;16) has a favorable prognosis.
Academic Article Rearrangements of the MLL gene in therapy-related acute myeloid leukemia in patients previously treated with agents targeting DNA-topoisomerase II.
Academic Article A morphologic and cytochemical study of acute myelomonocytic leukemia with abnormal marrow eosinophils associated with inv(16)(p13q22).
Academic Article Association of a chromosomal 3;21 translocation with the blast phase of chronic myelogenous leukemia.
Academic Article Assignment of the GM-CSF, CSF-1, and FMS genes to human chromosome 5 provides evidence for linkage of a family of genes regulating hematopoiesis and for their involvement in the deletion (5q) in myeloid disorders.
Academic Article The relationship between secondary chromosomal abnormalities and blast transformation in chronic myelogenous leukemia.
Academic Article Der(5)t(5;7)(q11.2;p11.2): a new recurring abnormality in malignant myeloid disorders.
Academic Article Acute myelomonocytic leukemia with abnormal eosinophils presenting as an ovarian mass: a report of two cases and a review of the literature.
Academic Article Assignment of CSF-1 to 5q33.1: evidence for clustering of genes regulating hematopoiesis and for their involvement in the deletion of the long arm of chromosome 5 in myeloid disorders.
Academic Article Short remission durations in therapy-related leukemia despite cytogenetic complete responses to high-dose cytarabine.
Academic Article Management of myelodysplastic syndromes.
Academic Article Chromosomal loss and deletion are the most common mechanisms for loss of heterozygosity from chromosomes 5 and 7 in malignant myeloid disorders.
Academic Article Persistence of the 8;21 translocation in patients with acute myeloid leukemia type M2 in long-term remission.
Academic Article Interleukin-4 and interleukin-5 map to human chromosome 5 in a region encoding growth factors and receptors and are deleted in myeloid leukemias with a del(5q).
Academic Article The predictive value of initial cytogenetic studies in 148 adults with acute nonlymphocytic leukemia: a 12-year study (1970-1982).
Academic Article Association of an inversion of chromosome 16 with abnormal marrow eosinophils in acute myelomonocytic leukemia. A unique cytogenetic-clinicopathological association.
Academic Article Detection of MLL gene rearrangements in adult acute lymphoblastic leukemia. A Cancer and Leukemia Group B study.
Academic Article Evidence for the involvement of GM-CSF and FMS in the deletion (5q) in myeloid disorders.
Academic Article Dasatinib induces rapid hematologic and cytogenetic responses in adult patients with Philadelphia chromosome positive acute lymphoblastic leukemia with resistance or intolerance to imatinib: interim results of a phase 2 study.
Academic Article Clinical and cytogenetic correlations in 63 patients with therapy-related myelodysplastic syndromes and acute nonlymphocytic leukemia: further evidence for characteristic abnormalities of chromosomes no. 5 and 7.
Academic Article Certain HLA antigens are associated with specific morphologic and cytogenetic subsets of acute myeloid leukemia.
Academic Article Response to 5-azacytidine in patients with refractory acute nonlymphocytic leukemia and association with chromosome findings.
Academic Article Cytogenetic clonality in myelodysplastic syndromes studied with fluorescence in situ hybridization: lineage, response to growth factor therapy, and clone expansion.
Academic Article A recurring chromosome rearrangement, dic(16;22), in acute nonlymphocytic leukemia.
Academic Article Chromosome changes in hematologic malignancies.
Academic Article Establishment of a leukemia cell line with i(12p) from a patient with a mediastinal germ cell tumor and acute lymphoblastic leukemia.
Academic Article Recent clinical trials in acute lymphocytic leukemia by the Cancer and Leukemia Group B.
Academic Article Comparison of cytogenetic and molecular genetic detection of t(8;21) and inv(16) in a prospective series of adults with de novo acute myeloid leukemia: a Cancer and Leukemia Group B Study.
Academic Article Genomic DNA breakpoints in AML1/RUNX1 and ETO cluster with topoisomerase II DNA cleavage and DNase I hypersensitive sites in t(8;21) leukemia.
Academic Article Balanced chromosome abnormalities inv(16) and t(15;17) in therapy-related myelodysplastic syndromes and acute leukemia: report from an international workshop.
Academic Article Isolated trisomy of chromosomes 8, 11, 13 and 21 is an adverse prognostic factor in adults with de novo acute myeloid leukemia: results from Cancer and Leukemia Group B 8461.
Academic Article Pretreatment cytogenetic abnormalities are predictive of induction success, cumulative incidence of relapse, and overall survival in adult patients with de novo acute myeloid leukemia: results from Cancer and Leukemia Group B (CALGB 8461).
Academic Article RAS, FLT3, and TP53 mutations in therapy-related myeloid malignancies with abnormalities of chromosomes 5 and 7.
Academic Article Core binding factor acute myeloid leukemia. Cancer and Leukemia Group B (CALGB) Study 8461.
Academic Article Select high-risk genetic features predict earlier progression following chemoimmunotherapy with fludarabine and rituximab in chronic lymphocytic leukemia: justification for risk-adapted therapy.
Academic Article t(3;21)(q26;q22): a recurring chromosomal abnormality in therapy-related myelodysplastic syndrome and acute myeloid leukemia.
Academic Article Treatment-influenced associations of PML-RARa mutations, FLT3 mutations, and additional chromosome abnormalities in relapsed acute promyelocytic leukemia.
Academic Article Acute myeloid leukemia: the challenge of unfavorable cytogenetics.
Academic Article Specific chromosomal abnormalities in acute nonlymphocytic leukemia correlate with drug susceptibility in vivo.
Academic Article Nonrandom chromosome abnormalities in angioimmunoblastic lymphadenopathy.
Academic Article Fusion of the dominant negative transcription regulator CHOP with a novel gene FUS by translocation t(12;16) in malignant liposarcoma.
Academic Article Clinical and prognostic significance of chromosomal abnormalities in childhood acute myeloid leukemia de novo.
Academic Article Phase II study of nilotinib in patients with relapsed or refractory Philadelphia chromosome--positive acute lymphoblastic leukemia.
Academic Article inv(16)/t(16;16) acute myeloid leukemia with non-type A CBFB-MYH11 fusions associate with distinct clinical and genetic features and lack KIT mutations.
Academic Article The spectrum of somatic mutations in high-risk acute myeloid leukaemia with -7/del(7q).
Academic Article BCR-ABL1 compound mutations combining key kinase domain positions confer clinical resistance to ponatinib in Ph chromosome-positive leukemia.
Academic Article Genomic aberrations in myeloid sarcoma without blood or bone marrow involvement: characterization of formalin-fixed paraffin-embedded samples by chromosomal microarrays.
Academic Article Autologous transplantation for Philadelphia chromosome-positive acute lymphoblastic leukemia achieves outcomes similar to allogeneic transplantation: results of CALGB Study 10001 (Alliance).
Academic Article Overexpression and knockout of miR-126 both promote leukemogenesis.
Academic Article Cytogenetic prioritization with inclusion of molecular markers predicts outcome in previously untreated patients with chronic lymphocytic leukemia treated with fludarabine or fludarabine plus cyclophosphamide: a long-term follow-up study of the US intergroup phase III trial E2997.
Academic Article Is there a best TKI for chronic phase CML?
Academic Article Clinical impact of ABL1 kinase domain mutations and IKZF1 deletion in adults under age 60 with Philadelphia chromosome-positive (Ph+) acute lymphoblastic leukemia (ALL): molecular analysis of CALGB (Alliance) 10001 and 9665.
Academic Article Nilotinib in patients with Philadelphia chromosome-positive chronic myelogenous leukemia in blast crisis (CML-BC) who are resistant or intolerant to imatinib.
Academic Article Comparison of de novo vs. therapy-related acute leukemia (AL) and myelodysplastic syndromes (MDS) in adults with balanced chromosome aberrations of 11q23.
Academic Article A pediatric regimen for older adolescents and young adults with acute lymphoblastic leukemia: results of CALGB 10403.
Academic Article Therapy-related acute lymphoblastic leukemia is a distinct entity with adverse genetic features and clinical outcomes.
Academic Article Dasatinib and dexamethasone followed by hematopoietic cell transplantation for adults with Ph-positive ALL.
Academic Article Therapy-related myeloid neoplasms in 109 patients after radiation monotherapy.
Academic Article Effect of additional cytogenetic abnormalities on survival in arsenic trioxide-treated acute promyelocytic leukemia.
Search Criteria
  • Chromosomes Human Pair 2