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One or more keywords matched the following items that are connected to Kossiakoff, Anthony
Item TypeName
Concept Peptide Fragments
Concept Receptors, Peptide
Concept Peptide Library
Academic Article X-ray structure of human relaxin at 1.5 A. Comparison to insulin and implications for receptor binding determinants.
Academic Article Biosynthetic phage display: a novel protein engineering tool combining chemical and genetic diversity.
Academic Article High affinity RNase S-peptide variants obtained by phage display have a novel "hot-spot" of binding energy.
Academic Article Structure of a phage display-derived variant of human growth hormone complexed to two copies of the extracellular domain of its receptor: evidence for strong structural coupling between receptor binding sites.
Academic Article The functional binding epitope of a high affinity variant of human growth hormone mapped by shotgun alanine-scanning mutagenesis: insights into the mechanisms responsible for improved affinity.
Academic Article Engineering subtilisin and its substrates for efficient ligation of peptide bonds in aqueous solution.
Academic Article Synthetic antibodies for specific recognition and crystallization of structured RNA.
Academic Article Dissecting the binding energy epitope of a high-affinity variant of human growth hormone: cooperative and additive effects from combining mutations from independently selected phage display mutagenesis libraries.
Academic Article Alternative views of functional protein binding epitopes obtained by combinatorial shotgun scanning mutagenesis.
Academic Article Comprehensive and quantitative mapping of energy landscapes for protein-protein interactions by rapid combinatorial scanning.
Academic Article Exploring the capacity of minimalist protein interfaces: interface energetics and affinity maturation to picomolar KD of a single-domain antibody with a flat paratope.
Academic Article Crystal structure of the kringle 2 domain of tissue plasminogen activator at 2.4-A resolution.
Academic Article Crystal structure of full-length KcsA in its closed conformation.
Academic Article High-throughput generation of synthetic antibodies from highly functional minimalist phage-displayed libraries.
Academic Article Characterization of engineered actin binding proteins that control filament assembly and structure.
Academic Article A portable RNA sequence whose recognition by a synthetic antibody facilitates structural determination.
Academic Article Generating conformation-specific synthetic antibodies to trap proteins in selected functional states.
Academic Article Applications for an engineered Protein-G variant with a pH controllable affinity to antibody fragments.
Academic Article Scalable high throughput selection from phage-displayed synthetic antibody libraries.
Academic Article Phage display selections for affinity reagents to membrane proteins in nanodiscs.
Academic Article Assessment of a method to characterize antibody selectivity and specificity for use in immunoprecipitation.
Academic Article A New Versatile Immobilization Tag Based on the Ultra High Affinity and Reversibility of the Calmodulin-Calmodulin Binding Peptide Interaction.
Academic Article Optimizing Production of Antigens and Fabs in the Context of Generating Recombinant Antibodies to Human Proteins.
Academic Article Conformational Chaperones for Structural Studies of Membrane Proteins Using Antibody Phage Display with Nanodiscs.
Academic Article Specific Recognition of a Single-Stranded RNA Sequence by a Synthetic Antibody Fragment.
Academic Article Generating Conformation and Complex-Specific Synthetic Antibodies.
Academic Article Targeted rescue of cancer-associated IDH1 mutant activity using an engineered synthetic antibody.
Academic Article Engineered synthetic antibodies as probes to quantify the energetic contributions of ligand binding to conformational changes in proteins.
Academic Article Locking the Elbow: Improved Antibody Fab Fragments as Chaperones for Structure Determination.
Academic Article The structure of the C-terminal domain of the nucleoprotein from the Bundibugyo strain of the Ebola virus in complex with a pan-specific synthetic Fab.
Academic Article Development of "Plug and Play" Fiducial Marks for Structural Studies of GPCR Signaling Complexes by Single-Particle Cryo-EM.
Academic Article Recognition of an a-helical hairpin in P22 large terminase by a synthetic antibody fragment.
Academic Article Engineered Ultra-High Affinity Synthetic Antibodies for SARS-CoV-2 Neutralization and Detection.
Academic Article Inhibition of Cancer Cell Adhesion, Migration and Proliferation by a Bispecific Antibody that Targets two Distinct Epitopes on av Integrins.
Academic Article Synthetic Antibodies Detect Distinct Cellular States of Chromosome Passenger Complex Proteins.
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