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Froelich, Christopher
One or more keywords matched the following items that are connected to Froelich, Christopher
Item TypeName
Concept Membrane Glycoproteins
Academic Article Lymphocyte granule-mediated apoptosis: matters of viral mimicry and deadly proteases.
Academic Article An antimicrobial activity of cytolytic T cells mediated by granulysin.
Academic Article Granzyme B independently of perforin mediates noncytolytic intracellular inactivation of vesicular stomatitis virus.
Academic Article Granzyme B/perforin-mediated apoptosis of Jurkat cells results in cleavage of poly(ADP-ribose) polymerase to the 89-kDa apoptotic fragment and less abundant 64-kDa fragment.
Academic Article Human perforin: rapid enrichment by immobilized metal affinity chromatography (IMAC) for whole cell cytotoxicity assays.
Academic Article Nuclear targeting of the serine protease granzyme A (fragmentin-1).
Academic Article BCL-2 blocks perforin-induced nuclear translocation of granzymes concomitant with protection against the nuclear events of apoptosis.
Academic Article P-glycoprotein does not protect cells against cytolysis induced by pore-forming proteins.
Academic Article Purification and use of granzyme B.
Academic Article Entry and trafficking of granzyme B in target cells during granzyme B-perforin-mediated apoptosis.
Academic Article Perforin-dependent nuclear entry of granzyme B precedes apoptosis, and is not a consequence of nuclear membrane dysfunction.
Academic Article Cytotoxic cell granule-mediated apoptosis: perforin delivers granzyme B-serglycin complexes into target cells without plasma membrane pore formation.
Academic Article Cytosolic delivery of granzyme B by bacterial toxins: evidence that endosomal disruption, in addition to transmembrane pore formation, is an important function of perforin.
Academic Article Flow cytometry cannot assess surface binding of perforin to target cells.
Academic Article The human cytomegalovirus protein UL16 mediates increased resistance to natural killer cell cytotoxicity through resistance to cytolytic proteins.
Academic Article Perforin and granzyme B induce apoptosis in FasL-resistant colon carcinoma cells.
Academic Article The T cell death knell: immune-mediated tumor death in renal cell carcinoma.
Academic Article Myeloma cells are highly sensitive to the granule exocytosis pathway mediated by WT1-specific cytotoxic T lymphocytes.
Academic Article Human neutrophils lack granzyme A, granzyme B, and perforin.
Academic Article A clathrin/dynamin- and mannose-6-phosphate receptor-independent pathway for granzyme B-induced cell death.
Academic Article Detection of functional cell surface perforin by flow cytometry.
Academic Article Detection of human perforin by ELISpot and ELISA: ex vivo identification of virus-specific cells.
Academic Article FLIP prevents apoptosis induced by death receptors but not by perforin/granzyme B, chemotherapeutic drugs, and gamma irradiation.
Academic Article Hepatic natural killer cells exclusively kill splenic/blood natural killer-resistant tumor cells by the perforin/granzyme pathway.
Academic Article Cytotoxic granule-mediated apoptosis: unraveling the complex mechanism.
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