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Search Results to Christopher Froelich

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One or more keywords matched the following items that are connected to Froelich, Christopher

Item TypeName
Concept Cell Membrane Permeability
Concept Cell Membrane
Concept Membrane Glycoproteins
Concept Membrane Proteins
Concept Membrane Lipids
Concept Intracellular Membranes
Concept Synovial Membrane
Concept Complement Membrane Attack Complex
Concept Membrane Potentials
Concept Membrane Microdomains
Concept Membrane Potential, Mitochondrial
Academic Article Lymphocyte granule-mediated apoptosis: matters of viral mimicry and deadly proteases.
Academic Article An antimicrobial activity of cytolytic T cells mediated by granulysin.
Academic Article Granzyme B independently of perforin mediates noncytolytic intracellular inactivation of vesicular stomatitis virus.
Academic Article Granzyme B/perforin-mediated apoptosis of Jurkat cells results in cleavage of poly(ADP-ribose) polymerase to the 89-kDa apoptotic fragment and less abundant 64-kDa fragment.
Academic Article Human perforin: rapid enrichment by immobilized metal affinity chromatography (IMAC) for whole cell cytotoxicity assays.
Academic Article Nuclear targeting of the serine protease granzyme A (fragmentin-1).
Academic Article BCL-2 blocks perforin-induced nuclear translocation of granzymes concomitant with protection against the nuclear events of apoptosis.
Academic Article P-glycoprotein does not protect cells against cytolysis induced by pore-forming proteins.
Academic Article Purification and use of granzyme B.
Academic Article Entry and trafficking of granzyme B in target cells during granzyme B-perforin-mediated apoptosis.
Academic Article Perforin-dependent nuclear entry of granzyme B precedes apoptosis, and is not a consequence of nuclear membrane dysfunction.
Academic Article Cytotoxic cell granule-mediated apoptosis: perforin delivers granzyme B-serglycin complexes into target cells without plasma membrane pore formation.
Academic Article Cytosolic delivery of granzyme B by bacterial toxins: evidence that endosomal disruption, in addition to transmembrane pore formation, is an important function of perforin.
Academic Article Cell death-associated translocation of plasma membrane components induced by CTL.
Academic Article Flow cytometry cannot assess surface binding of perforin to target cells.
Academic Article A distinct pathway of cell-mediated apoptosis initiated by granulysin.
Academic Article The human cytomegalovirus protein UL16 mediates increased resistance to natural killer cell cytotoxicity through resistance to cytolytic proteins.
Academic Article Perforin and granzyme B induce apoptosis in FasL-resistant colon carcinoma cells.
Academic Article SPI-CI and SPI-6 cooperate in the protection from effector cell-mediated cytotoxicity.
Academic Article The T cell death knell: immune-mediated tumor death in renal cell carcinoma.
Academic Article A role for the granzyme B inhibitor serine protease inhibitor 6 in CD8+ memory cell homeostasis.
Academic Article Myeloma cells are highly sensitive to the granule exocytosis pathway mediated by WT1-specific cytotoxic T lymphocytes.
Academic Article Human neutrophils lack granzyme A, granzyme B, and perforin.
Academic Article A clathrin/dynamin- and mannose-6-phosphate receptor-independent pathway for granzyme B-induced cell death.
Academic Article Granzyme B activates procaspase-3 which signals a mitochondrial amplification loop for maximal apoptosis.
Academic Article Detection of functional cell surface perforin by flow cytometry.
Academic Article Granzyme B translocates across the lipid membrane only in the presence of lytic agents.
Academic Article Perforin activity at membranes leads to invaginations and vesicle formation.
Academic Article Modulation of the tumor cell phenotype by IFN-gamma results in resistance of uveal melanoma cells to granule-mediated lysis by cytotoxic lymphocytes.
Academic Article A novel mechanism for protein delivery: granzyme B undergoes electrostatic exchange from serglycin to target cells.
Academic Article Detection of human perforin by ELISpot and ELISA: ex vivo identification of virus-specific cells.
Academic Article Human perforin permeabilizing activity, but not binding to lipid membranes, is affected by pH.
Academic Article Perforin rapidly induces plasma membrane phospholipid flip-flop.
Academic Article FLIP prevents apoptosis induced by death receptors but not by perforin/granzyme B, chemotherapeutic drugs, and gamma irradiation.
Academic Article Human granzyme B mediates cartilage proteoglycan degradation and is expressed at the invasive front of the synovium in rheumatoid arthritis.
Academic Article Hepatic natural killer cells exclusively kill splenic/blood natural killer-resistant tumor cells by the perforin/granzyme pathway.
Academic Article Cytotoxic granule-mediated apoptosis: unraveling the complex mechanism.
Academic Article Right place, right time.
Academic Article Degradation of Mcl-1 by granzyme B: implications for Bim-mediated mitochondrial apoptotic events.
Academic Article Deregulation of mitochondrial membrane potential by mitochondrial insertion of granzyme B and direct Hax-1 cleavage.
Academic Article Human perforin employs different avenues to damage membranes.
Academic Article Effects of MACPF/CDC proteins on lipid membranes.
Academic Article Membrane pore formation at protein-lipid interfaces.
Academic Article Perforin oligomers form arcs in cellular membranes: a locus for intracellular delivery of granzymes.
Academic Article Mouse cytotoxic T cell-derived granzyme B activates the mitochondrial cell death pathway in a Bim-dependent fashion.

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