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Search Results to Mark J. Ratain

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One or more keywords matched the following items that are connected to Ratain, Mark J.

Item TypeName
Concept Genotype
Academic Article Phenotype-genotype correlation of in vitro SN-38 (active metabolite of irinotecan) and bilirubin glucuronidation in human liver tissue with UGT1A1 promoter polymorphism.
Academic Article Gazing into a crystal ball-cancer therapy in the post-genomic era.
Academic Article UGT1A1*28 polymorphism as a determinant of irinotecan disposition and toxicity.
Academic Article Pharmacogenetics: a tool for individualizing antineoplastic therapy.
Academic Article Phase I clinical and pharmacogenetic study of weekly TAS-103 in patients with advanced cancer.
Academic Article Interethnic difference in the allelic distribution of human epidermal growth factor receptor intron 1 polymorphism.
Academic Article A pharmacogenetic study of uridine diphosphate-glucuronosyltransferase 2B7 in patients receiving morphine.
Academic Article Correspondence re: Raida, M. et al., prevalence of a common point mutation in the dihydropyrimidine dehydrogenase (DPD) gene within the 5'-splice donor site of intron 14 in patients with severe 5-fluorouracil (5-FU)-related toxicity compared with controls.
Academic Article "Irinogenetics" and UGT1A: from genotypes to haplotypes.
Academic Article Genetic variants in the UDP-glucuronosyltransferase 1A1 gene predict the risk of severe neutropenia of irinotecan.
Academic Article Haplotype structure of the UDP-glucuronosyltransferase 1A1 promoter in different ethnic groups.
Academic Article Personalized medicine: building the GPS to take us there.
Academic Article Hepatocyte nuclear factor-1 alpha is associated with UGT1A1, UGT1A9 and UGT2B7 mRNA expression in human liver.
Academic Article Global gene expression as a function of germline genetic variation.
Academic Article Lack of association between common polymorphisms in UGT1A9 and gene expression and activity.
Academic Article The Werner's syndrome 4330T>C (Cys1367Arg) gene variant does not affect the in vitro cytotoxicity of topoisomerase inhibitors and platinum compounds.
Academic Article A pharmacogenetic study of vorinostat glucuronidation.
Academic Article Vascular endothelial growth factor pathway.
Academic Article Identification, replication, and functional fine-mapping of expression quantitative trait loci in primary human liver tissue.
Academic Article A genome-wide association study identifies novel loci for paclitaxel-induced sensory peripheral neuropathy in CALGB 40101.
Academic Article Re: CYP2D6 genotype and tamoxifen response in postmenopausal women with endocrine-responsive breast cancer: the Breast International Group 1-98 trial.
Academic Article The UGT1A1*28 polymorphism correlates with erlotinib's effect on SN-38 glucuronidation.
Academic Article TPMT, UGT1A1 and DPYD: genotyping to ensure safer cancer therapy?
Academic Article Germline pharmacogenomics in oncology: decoding the patient for targeting therapy.
Academic Article Pharmacogenetics and pharmacogenomics of anticancer agents.
Academic Article Drug-metabolizing enzymes: evidence for clinical utility of pharmacogenomic tests.
Academic Article Pharmacogenetics of irinotecan: clinical perspectives on the utility of genotyping.
Academic Article UGT1A1*28 genotype affects the in-vitro glucuronidation of thyroxine in human livers.
Academic Article Pharmacogenetic testing for uridine diphosphate glucuronosyltransferase 1A1 polymorphisms: are we there yet?
Academic Article Glucuronidation by UGT1A1 is the dominant pathway of the metabolic disposition of belinostat in liver cancer patients.
Academic Article CYP2D6 genotype and tamoxifen activity: understanding interstudy variability in methodological quality.
Academic Article Dose-finding and pharmacokinetic study to optimize the dosing of irinotecan according to the UGT1A1 genotype of patients with cancer.
Academic Article Meaningful use of pharmacogenetics.
Academic Article Incorporating biomarkers into drug labeling.
Academic Article Loss of heterozygosity at the CYP2D6 locus in breast cancer: implications for germline pharmacogenetic studies.
Academic Article Adoption of a clinical pharmacogenomics implementation program during outpatient care--initial results of the University of Chicago "1,200 Patients Project".
Academic Article Establishment of CYP2D6 reference samples by multiple validated genotyping platforms.
Academic Article A pharmacogenetic study of aldehyde oxidase I in patients treated with XK469.
Academic Article Glucuronidation of OTS167 in Humans Is Catalyzed by UDP-Glucuronosyltransferases UGT1A1, UGT1A3, UGT1A8, and UGT1A10.
Academic Article Evidence for Clinical Implementation of Pharmacogenomics in Cardiac Drugs.
Academic Article Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for UGT1A1 and Atazanavir Prescribing.
Academic Article Clinical validity of new genetic biomarkers of irinotecan neutropenia: an independent replication study.
Academic Article Pharmacogenetic Discovery in CALGB (Alliance) 90401 and Mechanistic Validation of a VAC14 Polymorphism that Increases Risk of Docetaxel-Induced Neuropathy.
Academic Article ABC transporter polymorphisms are associated with irinotecan pharmacokinetics and neutropenia.
Academic Article Providing Balance in ASCO Clinical Practice Guidelines: CYP2D6 Genotyping and Tamoxifen Efficacy.
Academic Article A Pharmacogenetic Prediction Model of Progression-Free Survival in Breast Cancer using Genome-Wide Genotyping Data from CALGB 40502 (Alliance).
Academic Article Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for CYP2D6 and Tamoxifen Therapy.
Academic Article Analysis of comprehensive pharmacogenomic profiling to impact in-hospital prescribing.
Academic Article Pharmacogenomic genotypes define genetic ancestry in patients and enable population-specific genomic implementation.
Academic Article A New Liver Expression Quantitative Trait Locus Map From 1,183 Individuals Provides Evidence for Novel Expression Quantitative Trait Loci of Drug Response, Metabolic, and Sex-Biased Phenotypes.
Academic Article Pharmacogenomic-Based Decision Support to Predict Adherence to Medications.
Academic Article Clinical evaluation of germline polymorphisms associated with capecitabine toxicity in breast cancer: TBCRC-015.
Academic Article Influence of N-acetyltransferase 2 gene polymorphisms on the in vitro metabolism of the epidermal growth factor receptor inhibitor rociletinib.
Academic Article Validation of a Large Custom-Designed Pharmacogenomics Panel on an Array Genotyping Platform.
Academic Article Clinically actionable genotypes for anticancer prescribing among >1500 patients with pharmacogenomic testing.

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