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Ratain, Mark J.
One or more keywords matched the following items that are connected to
Ratain, Mark J.
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Isoenzymes
Academic Article
Genetic predisposition to the metabolism of irinotecan (CPT-11). Role of uridine diphosphate glucuronosyltransferase isoform 1A1 in the glucuronidation of its active metabolite (SN-38) in human liver microsomes.
Academic Article
Phase I clinical and pharmacokinetic study of protein kinase C-alpha antisense oligonucleotide ISIS 3521 administered in combination with 5-fluorouracil and leucovorin in patients with advanced cancer.
Academic Article
In vitro characterization of hepatic flavopiridol metabolism using human liver microsomes and recombinant UGT enzymes.
Academic Article
UGT pharmacogenomics: implications for cancer risk and cancer therapeutics.
Academic Article
Effects of ketoconazole on glucuronidation by UDP-glucuronosyltransferase enzymes.
Academic Article
Searching for tissue-specific expression pattern-linked nucleotides of UGT1A isoforms.
Academic Article
CYP2B6, CYP3A4, and CYP2C19 are responsible for the in vitro N-demethylation of meperidine in human liver microsomes.
Academic Article
Comparison of the drug-drug interactions potential of erlotinib and gefitinib via inhibition of UDP-glucuronosyltransferases.
Academic Article
Glucuronidation of OTS167 in Humans Is Catalyzed by UDP-Glucuronosyltransferases UGT1A1, UGT1A3, UGT1A8, and UGT1A10.
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Isoenzymes