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Ratain, Mark J.
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Ratain, Mark J.
Genetic predisposition to the metabolism of irinotecan (CPT-11). Role of uridine diphosphate glucuronosyltransferase isoform 1A1 in the glucuronidation of its active metabolite (SN-38) in human liver microsomes.
In vitro characterization of hepatic flavopiridol metabolism using human liver microsomes and recombinant UGT enzymes.
Epirubicin glucuronidation is catalyzed by human UDP-glucuronosyltransferase 2B7.
Haplotype structure of the UDP-glucuronosyltransferase 1A1 promoter in different ethnic groups.
Effects of ketoconazole on glucuronidation by UDP-glucuronosyltransferase enzymes.
CYP2B6, CYP3A4, and CYP2C19 are responsible for the in vitro N-demethylation of meperidine in human liver microsomes.
R(+)XK469 inhibits hydroxylation of S-warfarin by CYP2C9.
Comparison of the drug-drug interactions potential of erlotinib and gefitinib via inhibition of UDP-glucuronosyltransferases.
A pharmacogenetic study of vorinostat glucuronidation.
In vitro and in vivo oxidative metabolism and glucuronidation of anastrozole.
The UGT1A1*28 polymorphism correlates with erlotinib's effect on SN-38 glucuronidation.
UGT1A1*28 genotype affects the in-vitro glucuronidation of thyroxine in human livers.
Inhibition of paracetamol glucuronidation by tyrosine kinase inhibitors.
Glucuronidation by UGT1A1 is the dominant pathway of the metabolic disposition of belinostat in liver cancer patients.
Establishment of CYP2D6 reference samples by multiple validated genotyping platforms.
Glucuronidation of OTS167 in Humans Is Catalyzed by UDP-Glucuronosyltransferases UGT1A1, UGT1A3, UGT1A8, and UGT1A10.
Metabolism of megestrol acetate in vitro and the role of oxidative metabolites.