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One or more keywords matched the following items that are connected to Ratain, Mark J.
Item TypeName
Concept Microsomes, Liver
Concept Microsomes
Academic Article Genetic predisposition to the metabolism of irinotecan (CPT-11). Role of uridine diphosphate glucuronosyltransferase isoform 1A1 in the glucuronidation of its active metabolite (SN-38) in human liver microsomes.
Academic Article In vitro characterization of hepatic flavopiridol metabolism using human liver microsomes and recombinant UGT enzymes.
Academic Article Epirubicin glucuronidation is catalyzed by human UDP-glucuronosyltransferase 2B7.
Academic Article Haplotype structure of the UDP-glucuronosyltransferase 1A1 promoter in different ethnic groups.
Academic Article Effects of ketoconazole on glucuronidation by UDP-glucuronosyltransferase enzymes.
Academic Article CYP2B6, CYP3A4, and CYP2C19 are responsible for the in vitro N-demethylation of meperidine in human liver microsomes.
Academic Article R(+)XK469 inhibits hydroxylation of S-warfarin by CYP2C9.
Academic Article Comparison of the drug-drug interactions potential of erlotinib and gefitinib via inhibition of UDP-glucuronosyltransferases.
Academic Article A pharmacogenetic study of vorinostat glucuronidation.
Academic Article In vitro and in vivo oxidative metabolism and glucuronidation of anastrozole.
Academic Article The UGT1A1*28 polymorphism correlates with erlotinib's effect on SN-38 glucuronidation.
Academic Article UGT1A1*28 genotype affects the in-vitro glucuronidation of thyroxine in human livers.
Academic Article Inhibition of paracetamol glucuronidation by tyrosine kinase inhibitors.
Academic Article Glucuronidation by UGT1A1 is the dominant pathway of the metabolic disposition of belinostat in liver cancer patients.
Academic Article Establishment of CYP2D6 reference samples by multiple validated genotyping platforms.
Academic Article Glucuronidation of OTS167 in Humans Is Catalyzed by UDP-Glucuronosyltransferases UGT1A1, UGT1A3, UGT1A8, and UGT1A10.
Academic Article Metabolism of megestrol acetate in vitro and the role of oxidative metabolites.
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  • Microsomes