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Ratain, Mark J.
One or more keywords matched the following items that are connected to Ratain, Mark J.
Item TypeName
Concept Neutropenia
Academic Article Phase I study of escalating doses of mitoxantrone and paclitaxel with granulocyte-macrophage colony stimulating factor support.
Academic Article Treatment-related fatal sepsis from topotecan/cisplatin and topotecan/paclitaxel.
Academic Article Phase I study of ZD9331 on short daily intravenous bolus infusion for 5 days every 3 weeks with fixed dosing recommendations.
Academic Article Phase I and pharmacologic study of continuous infusion topotecan in combination with cisplatin in patients with advanced cancer: a Cancer and LeukemiaGroup B study.
Academic Article A Phase I study of raltitrexed and paclitaxel given every 3 weeks to patients with solid tumors.
Academic Article A phase I study of liposomal doxorubicin (Doxil) with topotecan.
Academic Article Dose-escalating study of capecitabine plus gemcitabine combination therapy in patients with advanced cancer.
Academic Article Phase I clinical and pharmacokinetic study of protein kinase C-alpha antisense oligonucleotide ISIS 3521 administered in combination with 5-fluorouracil and leucovorin in patients with advanced cancer.
Academic Article Phase I study to evaluate multiple regimens of intravenous 5-fluorouracil administered in combination with weekly gemcitabine in patients with advanced solid tumors: a potential broadly active regimen for advanced solid tumor malignancies.
Academic Article Genetic variants in the UDP-glucuronosyltransferase 1A1 gene predict the risk of severe neutropenia of irinotecan.
Academic Article A phase I trial of gemcitabine plus cladribine in patients with advanced hematologic malignant diseases.
Academic Article The role of SN-38 exposure, UGT1A1*28 polymorphism, and baseline bilirubin level in predicting severe irinotecan toxicity.
Academic Article Pharmacodynamic genes do not influence risk of neutropenia in cancer patients treated with moderately high-dose irinotecan.
Academic Article Pharmacokinetic modulation of oral etoposide by ketoconazole in patients with advanced cancer.
Academic Article Sequential therapy with dacarbazine and carmustine: a phase I study.
Academic Article A phase I study of intermittent infusion cladribine in patients with solid tumors.
Academic Article A phase I and pharmacokinetic study of the quinoxaline antitumour Agent R(+)XK469 in patients with advanced solid tumours.
Academic Article Phase I study of paclitaxel and topotecan in patients with advanced tumors: a cancer and leukemia group B study.
Academic Article Comprehensive pharmacogenetic analysis of irinotecan neutropenia and pharmacokinetics.
Academic Article Phase I study of the combination of losoxantrone and cyclophosphamide in patients with refractory solid tumours.
Academic Article Phase 1 dose escalation study of docetaxel with filgrastim support in patients with advanced solid tumors.
Academic Article Phase I study of an oral formulation of ZD9331 administered daily for 28 days.
Academic Article Phase I and pharmacokinetic study of 24-hour infusion 5-fluorouracil and leucovorin in patients with organ dysfunction.
Academic Article The relationship of polymorphisms in ABCC2 and SLCO1B3 with docetaxel pharmacokinetics and neutropenia: CALGB 60805 (Alliance).
Academic Article Clinical validity of new genetic biomarkers of irinotecan neutropenia: an independent replication study.
Academic Article ABC transporter polymorphisms are associated with irinotecan pharmacokinetics and neutropenia.
Academic Article Phase I study of lurbinectedin, a synthetic tetrahydroisoquinoline that inhibits activated transcription, induces DNA single- and double-strand breaks, on a weekly × 2 every-3-week schedule.
Academic Article An initial genetic analysis of gemcitabine-induced high-grade neutropenia in pancreatic cancer patients in CALGB 80303 (Alliance).
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  • Neutropenia