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Schwartz, Nancy B.
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overview This program has evolved from the basic biochemistry and enzymology of glycoconjugate structure, function, and synthesis to the study of glycoconjugates in cartilage development, including the identification of gene defects in disorders of skeletal development and chondrodystrophies and the underlying pathophysiology of the matrix deficiencies. A second major area of interest involves CNS development, and the role of gliogenesis and glial cell function in traumatic brain injury, infection and developmental disorders.
One or more keywords matched the following items that are connected to Schwartz, Nancy B.
Item TypeName
Concept Cartilage Diseases
Concept Cartilage
Academic Article Gene structure of chick cartilage chondroitin sulfate proteoglycan (aggrecan) core protein.
Academic Article Topography of glycosylation and UDP-xylose production.
Academic Article Xylosylation is an endoplasmic reticulum to Golgi event.
Academic Article S103L reactive chondroitin sulfate proteoglycan (aggrecan) mRNA expressed in developing chick brain and cartilage is encoded by a single gene.
Academic Article Age-dependent inhibition of neural crest migration by the notochord correlates with alterations in the S103L chondroitin sulfate proteoglycan.
Academic Article The nanomelic mutation in the aggrecan gene is expressed in chick chondrocytes and neurons.
Academic Article Structural and functional analysis of the chick chondroitin sulfate proteoglycan (aggrecan) promoter and enhancer region.
Academic Article Two immunologically and developmentally distinct chondroitin sulfate proteolglycans in embryonic chick brain.
Academic Article Chick cartilage chondroitin sulfate proteoglycan core protein. II. Nucleotide sequence of cDNA clone and localization of the S103L epitope.
Academic Article Ultrastructural characterization of embryonic chick cartilage proteoglycan core protein and the mapping of a monoclonal antibody epitope.
Academic Article UDP-glucuronate carboxy-lyase in cultured chondrocytes.
Academic Article Developmental expression of the HNK-1 carbohydrate epitope on aggrecan during chondrogenesis.
Academic Article Chondrodysplasias due to proteoglycan defects.
Academic Article Biosynthesis of chondroitin 4-sulfate-proteoglycan by a transplantable rat chondrosarcoma.
Academic Article Biochemical correlations in animal models of chondrodysplasias.
Academic Article Synthesis and structure of proteoglycan core protein.
Academic Article Biosynthesis of chondroitin sulfate. Role of phospholipids in the activity of UDP-D-galactose: D-xylose galactosyltransferase.
Academic Article Chondroitin sulfate glycosyltransferases in cultured chondrocytes. Turnover, oscillatory change during growth, and suppression by 5-bromodeoxyuridine.
Academic Article The biochemically and immunologically distinct CSPG of notochord is a product of the aggrecan gene.
Academic Article Defect in 3'-phosphoadenosine 5'-phosphosulfate formation in brachymorphic mice.
Academic Article Regulation of chondroitin sulfate synthesis. Effect of beta-xylosides on synthesis of chondroitin sulfate proteoglycan, chondroitin sulfate chains, and core protein.
Academic Article The irreversible effect of bromodeoxyuridine on chick chondrocytes.
Academic Article Biosynthesis of chondroitin sulfate: interaction between xylosyltransferase and galactosyltransferase.
Academic Article Developmental expression of S103L cross-reacting proteoglycans in embryonic chick.
Academic Article Kinetics of intracellular processing of chondroitin sulfate proteoglycan core protein and other matrix components.
Academic Article Mechanism for the decreased biosynthesis of cartilage proteoglycan in the scorbutic guinea pig.
Academic Article Defect in 3'-phosphoadenosine 5'-phosphosulfate synthesis in brachymorphic mice. I. Characterization of the defect.
Academic Article Immunological methods in the study of chondroitin sulfate proteoglycans.
Academic Article Synthesis of cartilage proteoglycans.
Academic Article Immunological evidence for two distinct chondroitin sulfate proteoglycan core proteins: differential expression in cartilage matrix deficient mice.
Academic Article Effect of beta-xylosides on synthesis of cartilage-specific proteoglycan in chondrocyte cultures.
Academic Article Stimulation of synthesis of free chondroitin sulfate chains by beta-D-xylosides in cultured cells.
Academic Article Chick cartilage chondroitin sulfate proteoglycan core protein. I. Generation and characterization of peptides and specificity for glycosaminoglycan attachment.
Academic Article Defect in proteoglycan synthesis in brachymorphic mice.
Academic Article Biosynthesis of chondroitin sulfate: immunoprecipitation of interacting xylosyltransferase and galactosyltransferase.
Academic Article Synthesis and secretion of an altered chondroitin sulfate proteoglycan.
Academic Article Defective PAPS-synthesis in epiphyseal cartilage from brachymorphic mice.
Academic Article Biosynthesis of chondroitin sulfate. Purification of UDP-D-xylose:core protein beta-D-xylosyltransferase by affinity chromatography.
Academic Article Location of xylosyltransferase in the cisternae of the rough endoplasmic reticulum of embryonic cartilage cells.
Academic Article Subcellular localization of the synthesis and glycosylation of chondroitin sulfate proteoglycan core protein.
Academic Article Brain aggrecan.
Academic Article The chondrodystrophy, nanomelia: biosynthesis and processing of the defective aggrecan precursor.
Academic Article Defect in 3'-phosphoadenosine 5'-phosphosulfate synthesis in brachymorphic mice. II. Tissue distribution of the defect.
Academic Article Stimulation of chondroitin sulfate proteoglycan production by chondrocytes in monolayer.
Academic Article cDNA cloning of chick cartilage chondroitin sulfate (aggrecan) core protein and identification of a stop codon in the aggrecan gene associated with the chondrodystrophy, nanomelia.
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  • Cartilage