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Dignam, James J.
One or more keywords matched the following properties of Dignam, James J.
PropertyValue
keywords competing risks
overview Dr. Dignam's primary research involves the design, conduct, and analysis of cancer clinical trials, including early development (phase I), pilot efficacy and safety (phase II), and definitive evaluation (phase III) trials. He is the Executive Director of the Statistics and Data Management Center for NRG Oncology, a National Cancer Institute sponsored multi-center clinical trials group with over 500 recruitment sites in North America and beyond and over 100 active clinical trials. Dr. Dignam's methodology interests include trial monitoring and early stopping rules, competing risks, hazard function estimation, and prognostic modeling. He also has engaged in and led investigations into sociodemographic factors such as race/ethnicity and BMI/obesity on cancer prognosis and treatment response. Courses taught include introductory biostatistics, clinical trials, survival analysis, and regression modeling methods.
One or more keywords matched the following items that are connected to Dignam, James J.
Item TypeName
Concept Risk Factors
Concept Risk
Concept Risk Assessment
Concept Risk Reduction Behavior
Academic Article Tamoxifen and chemotherapy for lymph node-negative, estrogen receptor-positive breast cancer.
Academic Article Five versus more than five years of tamoxifen therapy for breast cancer patients with negative lymph nodes and estrogen receptor-positive tumors.
Academic Article Prognosis and treatment of patients with breast tumors of one centimeter or less and negative axillary lymph nodes.
Academic Article Differences in breast cancer prognosis among African-American and Caucasian women.
Academic Article Mammographic density and breast cancer after ductal carcinoma in situ.
Academic Article How often do BRCA mutation carriers tell their young children of the family's risk for cancer? A study of parental disclosure of BRCA mutations to minors and young adults.
Academic Article Body mass index and outcomes in patients who receive adjuvant chemotherapy for colon cancer.
Academic Article Comments on: Yin W, Di G, Zhou L, Lu J, Liu G, Wu J, Shen K, Han Q, Shen Z, Shao Z. Time-varying pattern of recurrence risk for Chinese breast cancer patients.
Academic Article Family history of pancreatic cancer in a high-risk cancer clinic: implications for risk assessment.
Academic Article Re: Racial disparities in cancer survival among randomized clinical trials of the Southwest Oncology Group.
Academic Article A missing data approach to semi-competing risks problems.
Academic Article Uptake and timing of bilateral prophylactic salpingo-oophorectomy among BRCA1 and BRCA2 mutation carriers.
Academic Article Multiple imputation methods for inference on cumulative incidence with missing cause of failure.
Academic Article The use and interpretation of competing risks regression models.
Academic Article Predictors of locoregional recurrence after neoadjuvant chemotherapy: results from combined analysis of National Surgical Adjuvant Breast and Bowel Project B-18 and B-27.
Academic Article Prognosis after rectal cancer in blacks and whites participating in adjuvant therapy randomized trials.
Academic Article Obesity and breast cancer prognosis: an expanding body of evidence.
Academic Article Choice and interpretation of statistical tests used when competing risks are present.
Academic Article Glioma-associated oncogene family zinc finger 1 expression and metastasis in patients with head and neck squamous cell carcinoma treated with radiation therapy (RTOG 9003).
Academic Article Race and the prognostic influence of p53 in women with breast cancer.
Academic Article A nomogram for individualized estimation of survival among patients with brain metastasis.
Academic Article Bayesian approach for flexible modeling of semicompeting risks data.
Academic Article Hormone replacement therapy and breast cancer: heterogeneous risks by race, weight, and breast density.
Academic Article Assessing treatment benefit with competing risks not affected by the randomized treatment.
Academic Article Individualized dynamic prediction of prostate cancer recurrence with and without the initiation of a second treatment: Development and validation.
Academic Article A tissue biomarker-based model that identifies patients with a high risk of distant metastasis and differential survival by length of androgen deprivation therapy in RTOG protocol 92-02.
Academic Article Randomized Phase III Noninferiority Study Comparing Two Radiotherapy Fractionation Schedules in Patients With Low-Risk Prostate Cancer.
Academic Article Metastasis-Free Survival Is a Strong Surrogate of Overall Survival in Localized Prostate Cancer.
Academic Article Smoking, age, nodal disease, T stage, p16 status, and risk of distant metastases in patients with squamous cell cancer of the oropharynx.
Academic Article Quality of Life in Patients With Low-Risk Prostate Cancer Treated With Hypofractionated vs Conventional Radiotherapy: A Phase 3 Randomized Clinical Trial.
Academic Article Event-Free Survival, a Prostate-Specific Antigen-Based Composite End Point, Is Not a Surrogate for Overall Survival in Men With Localized Prostate Cancer Treated With Radiation.
Academic Article Early Endpoints in High-risk Localized Prostate Cancer: Exploratory Analysis of Three Radiation Therapy Oncology Group Phase 3 Studies.
Academic Article Risk Factors for Hospital Readmission in Patients with Interstitial Lung Disease.
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