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Dignam, James J.
One or more keywords matched the following properties of Dignam, James J.
PropertyValue
keywords survival analysis
overview Dr. Dignam's primary research involves the design, conduct, and analysis of cancer clinical trials, including early development (phase I), pilot efficacy and safety (phase II), and definitive evaluation (phase III) trials. He is the Executive Director of the Statistics and Data Management Center for NRG Oncology, a National Cancer Institute sponsored multi-center clinical trials group with over 500 recruitment sites in North America and beyond and over 100 active clinical trials. Dr. Dignam's methodology interests include trial monitoring and early stopping rules, competing risks, hazard function estimation, and prognostic modeling. He also has engaged in and led investigations into sociodemographic factors such as race/ethnicity and BMI/obesity on cancer prognosis and treatment response. Courses taught include introductory biostatistics, clinical trials, survival analysis, and regression modeling methods.
One or more keywords matched the following items that are connected to Dignam, James J.
Item TypeName
Concept Survival
Concept Survival Analysis
Concept Survival Rate
Concept Disease-Free Survival
Academic Article Sequential methotrexate and fluorouracil for the treatment of node-negative breast cancer patients with estrogen receptor-negative tumors: eight-year results from National Surgical Adjuvant Breast and Bowel Project (NSABP) B-13 and first report of findings from NSABP B-19 comparing methotrexate and fluorouracil with conventional cyclophosphamide, methotrexate, and fluorouracil.
Academic Article Tamoxifen and chemotherapy for lymph node-negative, estrogen receptor-positive breast cancer.
Academic Article Prognosis among African-American women and white women with lymph node negative breast carcinoma: findings from two randomized clinical trials of the National Surgical Adjuvant Breast and Bowel Project (NSABP).
Academic Article Five versus more than five years of tamoxifen therapy for breast cancer patients with negative lymph nodes and estrogen receptor-positive tumors.
Academic Article Methods for bounding the marginal survival distribution.
Academic Article Early stopping of a clinical trial when there is evidence of no treatment benefit: protocol B-14 of the National Surgical Adjuvant Breast and Bowel Project.
Academic Article Tamoxifen in treatment of intraductal breast cancer: National Surgical Adjuvant Breast and Bowel Project B-24 randomised controlled trial.
Academic Article Pathologic findings from the National Surgical Adjuvant Breast Project (NSABP) eight-year update of Protocol B-17: intraductal carcinoma.
Academic Article Prognosis and treatment of patients with breast tumors of one centimeter or less and negative axillary lymph nodes.
Academic Article Prevention of invasive breast cancer in women with ductal carcinoma in situ: an update of the National Surgical Adjuvant Breast and Bowel Project experience.
Academic Article Outcomes among African-Americans and Caucasians in colon cancer adjuvant therapy trials: findings from the National Surgical Adjuvant Breast and Bowel Project.
Academic Article Findings from recent National Surgical Adjuvant Breast and Bowel Project adjuvant studies in stage I breast cancer.
Academic Article Differences in breast cancer prognosis among African-American and Caucasian women.
Academic Article Efficacy of systemic adjuvant therapy for breast cancer in African-American and Caucasian women.
Academic Article Five versus more than five years of tamoxifen for lymph node-negative breast cancer: updated findings from the National Surgical Adjuvant Breast and Bowel Project B-14 randomized trial.
Academic Article Benefits and costs of interventions to improve breast cancer outcomes in African American women.
Academic Article Is patient travel distance associated with survival on phase II clinical trials in oncology?
Academic Article Toward optimal screening strategies for older women. Costs, benefits, and harms of breast cancer screening by age, biology, and health status.
Academic Article Obesity, tamoxifen use, and outcomes in women with estrogen receptor-positive early-stage breast cancer.
Academic Article Colorectal cancer and race: understanding the differences in outcomes between African Americans and whites.
Academic Article Effects of obesity and race on prognosis in lymph node-negative, estrogen receptor-negative breast cancer.
Academic Article Body mass index and outcomes in patients who receive adjuvant chemotherapy for colon cancer.
Academic Article The ongoing search for the sources of the breast cancer survival disparity.
Academic Article Treatment of lymph-node-negative, oestrogen-receptor-positive breast cancer: long-term findings from National Surgical Adjuvant Breast and Bowel Project randomised clinical trials.
Academic Article Re: Racial disparities in cancer survival among randomized clinical trials of the Southwest Oncology Group.
Academic Article Epidermal growth factor receptor inhibitor gefitinib added to chemoradiotherapy in locally advanced head and neck cancer.
Academic Article Long-term outcomes of invasive ipsilateral breast tumor recurrences after lumpectomy in NSABP B-17 and B-24 randomized clinical trials for DCIS.
Academic Article Multiple imputation methods for inference on cumulative incidence with missing cause of failure.
Academic Article p53 as a marker of prognosis in African-American women with breast cancer.
Academic Article Conditional survival and the choice of conditioning set for patients with colon cancer: an analysis of NSABP trials C-03 through C-07.
Academic Article Outcomes among black patients with stage II and III colon cancer receiving chemotherapy: an analysis of ACCENT adjuvant trials.
Academic Article Predictors of competing mortality in advanced head and neck cancer.
Academic Article Diffusing capacity predicts long-term survival after lung resection for cancer.
Academic Article Optimization of response classification criteria for patients with malignant pleural mesothelioma.
Academic Article Estimating breast cancer-specific and other-cause mortality in clinical trial and population-based cancer registry cohorts.
Academic Article Lumpectomy and radiation therapy for the treatment of intraductal breast cancer: findings from National Surgical Adjuvant Breast and Bowel Project B-17.
Academic Article Tamoxifen, radiation therapy, or both for prevention of ipsilateral breast tumor recurrence after lumpectomy in women with invasive breast cancers of one centimeter or less.
Academic Article Prognosis after rectal cancer in blacks and whites participating in adjuvant therapy randomized trials.
Academic Article Population-based survival-cure analysis of ER-negative breast cancer.
Academic Article Glioma-associated oncogene family zinc finger 1 expression and metastasis in patients with head and neck squamous cell carcinoma treated with radiation therapy (RTOG 9003).
Academic Article Race and the prognostic influence of p53 in women with breast cancer.
Academic Article A nomogram for individualized estimation of survival among patients with brain metastasis.
Academic Article Lung volume measurements as a surrogate marker for patient response in malignant pleural mesothelioma.
Academic Article Multiple imputation methods for nonparametric inference on cumulative incidence with missing cause of failure.
Academic Article A randomized trial of bevacizumab for newly diagnosed glioblastoma.
Academic Article Bayesian approach for flexible modeling of semicompeting risks data.
Academic Article A tissue biomarker-based model that identifies patients with a high risk of distant metastasis and differential survival by length of androgen deprivation therapy in RTOG protocol 92-02.
Academic Article Duration of androgen suppression before radiotherapy for localized prostate cancer: radiation therapy oncology group randomized clinical trial 9910.
Academic Article Radiation with or without Antiandrogen Therapy in Recurrent Prostate Cancer.
Academic Article A Multiresolution Hazard Model for Multicenter Survival Studies: Application to Tamoxifen Treatment in Early Stage Breast Cancer.
Academic Article Flexible modeling of the hazard rate and treatment effects in long-term survival studies.
Academic Article Duration of Androgen Deprivation in Locally Advanced Prostate Cancer: Long-Term Update of NRG Oncology RTOG 9202.
Academic Article Metastasis-Free Survival Is a Strong Surrogate of Overall Survival in Localized Prostate Cancer.
Academic Article Detecting a Survival Benefit to Dose Escalation-Reply.
Academic Article Quality of Life in Patients With Low-Risk Prostate Cancer Treated With Hypofractionated vs Conventional Radiotherapy: A Phase 3 Randomized Clinical Trial.
Academic Article Event-Free Survival, a Prostate-Specific Antigen-Based Composite End Point, Is Not a Surrogate for Overall Survival in Men With Localized Prostate Cancer Treated With Radiation.
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  • Survival