| Item Type | Name |
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Concept
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Gout
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Concept
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Gout Suppressants
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Academic Article
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Does diuretic use increase the risk of recurrent gout flares?
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Academic Article
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We can make gout management more successful now.
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Academic Article
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Update on emerging urate-lowering therapies.
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Academic Article
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Women with gout: efficacy and safety of urate-lowering with febuxostat and allopurinol.
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Academic Article
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Neurodevelopmental impairment and deranged PRPP and purine nucleotide synthesis in inherited superactivity of PRPP synthetase.
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Academic Article
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Clinical aspects of monosodium urate monohydrate crystal deposition disease (gout).
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Academic Article
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Phosphoribosylpyrophosphate synthetase overactivity as a cause of uric acid overproduction in a young woman.
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Academic Article
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Effects of febuxostat versus allopurinol and placebo in reducing serum urate in subjects with hyperuricemia and gout: a 28-week, phase III, randomized, double-blind, parallel-group trial.
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Academic Article
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Outcome measures for acute and chronic gout.
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Academic Article
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Febuxostat compared with allopurinol in patients with hyperuricemia and gout.
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Academic Article
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Tophaceous gout: quantitative evaluation by direct physical measurement.
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Academic Article
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Compliance with allopurinol therapy among managed care enrollees with gout: a retrospective analysis of administrative claims.
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Academic Article
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Febuxostat, a novel nonpurine selective inhibitor of xanthine oxidase: a twenty-eight-day, multicenter, phase II, randomized, double-blind, placebo-controlled, dose-response clinical trial examining safety and efficacy in patients with gout.
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Academic Article
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The urate-lowering efficacy and safety of febuxostat in the treatment of the hyperuricemia of gout: the CONFIRMS trial.
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Academic Article
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What do I need to know about gout?
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Academic Article
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Tophus measurement as an outcome measure for clinical trials of chronic gout: progress and research priorities.
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Academic Article
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Serum urate in chronic gout--will it be the first validated soluble biomarker in rheumatology?
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Academic Article
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Efficacy and tolerability of pegloticase for the treatment of chronic gout in patients refractory to conventional treatment: two randomized controlled trials.
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Academic Article
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Reduction of plasma urate levels following treatment with multiple doses of pegloticase (polyethylene glycol-conjugated uricase) in patients with treatment-failure gout: results of a phase II randomized study.
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Academic Article
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Clinical efficacy and safety of successful longterm urate lowering with febuxostat or allopurinol in subjects with gout.
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Academic Article
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Quality of life and disability in patients with treatment-failure gout.
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Academic Article
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Patient-reported outcomes in chronic gout: a report from OMERACT 10.
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Academic Article
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Treating hyperuricemia of gout: safety and efficacy of febuxostat and allopurinol in older versus younger subjects.
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Academic Article
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Inherited superactivity of phosphoribosylpyrophosphate synthetase: association of uric acid overproduction and sensorineural deafness.
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Academic Article
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Outcome evaluations in gout.
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Academic Article
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Determinants of the clinical outcomes of gout during the first year of urate-lowering therapy.
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Academic Article
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Bringing it all together: a novel approach to the development of response criteria for chronic gout clinical trials.
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Academic Article
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Urate transporters: transforming the face of hyperuricemia and gout.
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Academic Article
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Diabetes and gout: efficacy and safety of febuxostat and allopurinol.
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Academic Article
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Infusion-related reactions with pegloticase, a recombinant uricase for the treatment of chronic gout refractory to conventional therapy.
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Academic Article
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Tophus burden reduction with pegloticase: results from phase 3 randomized trials and open-label extension in patients with chronic gout refractory to conventional therapy.
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Academic Article
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Long-term management of gout: nonpharmacologic and pharmacologic therapies.
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Academic Article
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Pegloticase immunogenicity: the relationship between efficacy and antibody development in patients treated for refractory chronic gout.
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Academic Article
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Long-term safety of pegloticase in chronic gout refractory to conventional treatment.
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Academic Article
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An open-label, 6-month study of allopurinol safety in gout: The LASSO study.
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Academic Article
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Impact of Febuxostat on Renal Function in Gout Patients With Moderate-to-Severe Renal Impairment.
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Academic Article
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Summary of the 2015 Purine and Pyrimidine Society/Purine Metabolic Patients Association H. Anne Simmonds Memorial Lecture.
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Academic Article
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Lesinurad Combined With Allopurinol: A Randomized, Double-Blind, Placebo-Controlled Study in Gout Patients With an Inadequate Response to Standard-of-Care Allopurinol (a US-Based Study).
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Academic Article
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Genetic aspects of gout.
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Academic Article
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Identification of distinct PRS1 mutations in two patients with X-linked phosphoribosylpyrophosphate synthetase superactivity.
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Academic Article
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Increased PP-ribose-P synthetase activity: a genetic abnormality leading to excessive purine production and gout.
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Academic Article
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Recent advances in the identification of enzyme abnormalities underlying excessive purine synthesis in man.
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Academic Article
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Rheumatology.
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Academic Article
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A modified Delphi exercise to determine the extent of consensus with OMERACT outcome domains for studies of acute and chronic gout.
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Academic Article
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Gout with purine overproduction due to increased phosphoribosylpyrophosphate synthetase activity.
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Academic Article
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Human phosphoribosylpyrophosphate synthetase: increased enzyme specific activity in a family with gout and excessive purine synthesis.
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Academic Article
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Efficacy and safety of febuxostat extended release and immediate release in patients with gout and moderate renal impairment: phase II placebo-controlled study.
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Academic Article
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Febuxostat in the treatment of gout: 5-yr findings of the FOCUS efficacy and safety study.
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Academic Article
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Diminished affinity for purine substrates as a basis for gout with mild deficiency of hypoxanthine-guanine phosphoribosyltransferase.
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Academic Article
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A revised estimate of the burden of illness of gout.
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Academic Article
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Inflammation: a possible mechanism for a causative role of hyperuricemia/gout in cardiovascular disease.
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Academic Article
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Magnetic resonance imaging in the quantitative assessment of gouty tophi.
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Academic Article
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Cardiovascular Safety of Febuxostat or Allopurinol in Patients with Gout.
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Academic Article
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Gout with superactive phosphoribosylpyrophosphate synthetase due to increased enzyme catalytic rate.
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Academic Article
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Diagnostic evaluation of phosphoribosylpyrophosphate synthetase activities in hemolysates.
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Academic Article
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Purine overproduction in man associated with increased phosphoribosylpyrophosphate synthetase activity.
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Academic Article
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Evaluation of the role of 5-phosphoribosyl-alpha-1-pyrophosphate synthetase in congenital hyperuricemia and gout: a simple isotopic assay and an activity stain for the enzyme.
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Academic Article
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Patterns of phosphoribosylpyrophosphate and ribose-5-phosphate concentration and generation in fibroblasts from patients with gout and purine overproduction.
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Academic Article
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Fibroblast phosphoribosylpyrophosphate and ribose-5-phosphate concentration and generation in gout with purine overproduction.
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Academic Article
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Work productivity loss due to flares in patients with chronic gout refractory to conventional therapy.
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Academic Article
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Efficacy and Safety of Febuxostat Extended and Immediate Release in Patients With Gout and Renal Impairment: A Phase III Placebo-Controlled Study.
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Academic Article
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Evaluation of the Relationship Between Serum Urate Levels, Clinical Manifestations of Gout, and Death From Cardiovascular Causes in Patients Receiving Febuxostat or Allopurinol in an Outcomes Trial.
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Grant
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REGULATION OF PURINE NUCLEOTIDE SYNTHESIS IN HUMANS
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Grant
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REGULATION OF PURINE NUCLEOTIDE SYNTHESIS IN MAN
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