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Becker, Michael
One or more keywords matched the following items that are connected to Becker, Michael
Item TypeName
Concept Adenine Nucleotides
Concept Guanine Nucleotides
Concept Purine Nucleotides
Concept Nucleotides
Concept Pyrimidine Nucleotides
Academic Article PRPP and purine nucleotide metabolism in human lymphoblasts with both PRPP synthetase superactivity and HGPRT deficiency.
Academic Article Regulation of purine nucleotide synthesis in human B lymphoblasts with both hypoxanthine-guanine phosphoribosyltransferase deficiency and phosphoribosylpyrophosphate synthetase superactivity.
Academic Article Neurodevelopmental impairment and deranged PRPP and purine nucleotide synthesis in inherited superactivity of PRPP synthetase.
Academic Article Point mutations in PRPS1, the gene encoding the PRPP synthetase (PRS) 1 isoform, underlie X-linked PRS superactivity associated with purine nucleotide inhibitor-resistance.
Academic Article Accelerated transcription of PRPS1 in X-linked overactivity of normal human phosphoribosylpyrophosphate synthetase.
Academic Article Febuxostat (TMX-67), a novel, non-purine, selective inhibitor of xanthine oxidase, is safe and decreases serum urate in healthy volunteers.
Academic Article PP07: new approaches, new knowledge, new challenges in human purine and pyrimidine metabolism.
Academic Article In memoriam: J. Edwin Seegmiller, M.D. (1920-2006).
Academic Article Treating hyperuricemia of gout: safety and efficacy of febuxostat and allopurinol in older versus younger subjects.
Academic Article Regulation of purine synthesis de novo in human fibroblasts by purine nucleotides and phosphoribosylpyrophosphate.
Academic Article Inherited superactivity of phosphoribosylpyrophosphate synthetase: association of uric acid overproduction and sensorineural deafness.
Academic Article Determinants of the clinical outcomes of gout during the first year of urate-lowering therapy.
Academic Article SWOG S0910: a phase 2 trial of clofarabine/cytarabine/epratuzumab for relapsed/refractory acute lymphocytic leukaemia.
Academic Article Summary of the 2015 Purine and Pyrimidine Society/Purine Metabolic Patients Association H. Anne Simmonds Memorial Lecture.
Academic Article Purine metabolism in normal and thioguanine-resistant neuroblastoma.
Academic Article Inhibition of human 5-phosphoribosyl-1-pyrophosphate synthetase by 4-amino-8-(beta-D-ribofuranosylamino)-pyrimido[5,4-d]pyrimidine-5'- monophosphate: evidence for interaction at the ADP allosteric site.
Academic Article Mechanisms of accelerated purine nucleotide synthesis in human fibroblasts with superactive phosphoribosylpyrophosphate synthetases.
Academic Article Increased PP-ribose-P synthetase activity: a genetic abnormality leading to excessive purine production and gout.
Academic Article Recent advances in the identification of enzyme abnormalities underlying excessive purine synthesis in man.
Academic Article Superactive phosphoribosylpyrophosphate synthetase with altered regulatory and catalytic properties.
Academic Article Increased purine nucleotide degradation in the central nervous system (CNS) in PRPP synthetase superactivity.
Academic Article Purine nucleotide synthesis in lymphoblasts cultured from normal subjects and a patient with Lesch-Nyhan syndrome.
Academic Article Inherited phosphoribosylpyrophosphate synthetase superactivity due to aberrant inhibitor and activator responsiveness.
Academic Article Human X-linked phosphoribosylpyrophosphate synthetase superactivity is associated with distinct point mutations in the PRPS1 gene.
Academic Article Human erythrocyte phosphoribosylpyrophosphate synthetase. Subunit analysis and states of subunit association.
Academic Article Variant human phosphoribosylpyrophosphate synthetase altered in regulatory and catalytic functions.
Academic Article Phosphoribosylpyrophosphate synthetase superactivity. A study of five patients with catalytic defects in the enzyme.
Academic Article Effects of inosine on purine synthesis in normal and HGPRT-deficient human fibroblasts.
Academic Article Superactivity of human phosphoribosyl pyrophosphate synthetase due to altered regulation by nucleotide inhibitors and inorganic phosphate.
Academic Article Human phosphoribosylpyrophosphate synthetase: relation of activity and quaternary structure.
Academic Article Effects of oxipurinol on pyrimidine nucleotide synthesis in human lymphoblasts.
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