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One or more keywords matched the following items that are connected to Becker, Michael
Item TypeName
Concept Uric Acid
Concept Urate Oxidase
Academic Article We can make gout management more successful now.
Academic Article Update on emerging urate-lowering therapies.
Academic Article Women with gout: efficacy and safety of urate-lowering with febuxostat and allopurinol.
Academic Article Clinical aspects of monosodium urate monohydrate crystal deposition disease (gout).
Academic Article Phosphoribosylpyrophosphate synthetase overactivity as a cause of uric acid overproduction in a young woman.
Academic Article Febuxostat (TMX-67), a novel, non-purine, selective inhibitor of xanthine oxidase, is safe and decreases serum urate in healthy volunteers.
Academic Article Recent developments in our understanding of the renal basis of hyperuricemia and the development of novel antihyperuricemic therapeutics.
Academic Article Effects of febuxostat versus allopurinol and placebo in reducing serum urate in subjects with hyperuricemia and gout: a 28-week, phase III, randomized, double-blind, parallel-group trial.
Academic Article Febuxostat compared with allopurinol in patients with hyperuricemia and gout.
Academic Article Tophaceous gout: quantitative evaluation by direct physical measurement.
Academic Article Febuxostat, a novel nonpurine selective inhibitor of xanthine oxidase: a twenty-eight-day, multicenter, phase II, randomized, double-blind, placebo-controlled, dose-response clinical trial examining safety and efficacy in patients with gout.
Academic Article The urate-lowering efficacy and safety of febuxostat in the treatment of the hyperuricemia of gout: the CONFIRMS trial.
Academic Article What do I need to know about gout?
Academic Article Serum urate in chronic gout--will it be the first validated soluble biomarker in rheumatology?
Academic Article Efficacy and tolerability of pegloticase for the treatment of chronic gout in patients refractory to conventional treatment: two randomized controlled trials.
Academic Article Reduction of plasma urate levels following treatment with multiple doses of pegloticase (polyethylene glycol-conjugated uricase) in patients with treatment-failure gout: results of a phase II randomized study.
Academic Article Clinical efficacy and safety of successful longterm urate lowering with febuxostat or allopurinol in subjects with gout.
Academic Article Crystal-induced arthropathies: recent investigative advances.
Academic Article Treating hyperuricemia of gout: safety and efficacy of febuxostat and allopurinol in older versus younger subjects.
Academic Article Inherited superactivity of phosphoribosylpyrophosphate synthetase: association of uric acid overproduction and sensorineural deafness.
Academic Article Determinants of the clinical outcomes of gout during the first year of urate-lowering therapy.
Academic Article Urate transporters: transforming the face of hyperuricemia and gout.
Academic Article Infusion-related reactions with pegloticase, a recombinant uricase for the treatment of chronic gout refractory to conventional therapy.
Academic Article Tophus burden reduction with pegloticase: results from phase 3 randomized trials and open-label extension in patients with chronic gout refractory to conventional therapy.
Academic Article Long-term management of gout: nonpharmacologic and pharmacologic therapies.
Academic Article Pegloticase immunogenicity: the relationship between efficacy and antibody development in patients treated for refractory chronic gout.
Academic Article Long-term safety of pegloticase in chronic gout refractory to conventional treatment.
Academic Article An open-label, 6-month study of allopurinol safety in gout: The LASSO study.
Academic Article Genetic aspects of gout.
Academic Article Uricosuric effects of niridazole.
Academic Article Identification of distinct PRS1 mutations in two patients with X-linked phosphoribosylpyrophosphate synthetase superactivity.
Academic Article Increased PP-ribose-P synthetase activity: a genetic abnormality leading to excessive purine production and gout.
Academic Article Increased purine nucleotide degradation in the central nervous system (CNS) in PRPP synthetase superactivity.
Academic Article Gout with purine overproduction due to increased phosphoribosylpyrophosphate synthetase activity.
Academic Article Variant human phosphoribosylpyrophosphate synthetase altered in regulatory and catalytic functions.
Academic Article Febuxostat in the treatment of gout: 5-yr findings of the FOCUS efficacy and safety study.
Academic Article Gout with superactive phosphoribosylpyrophosphate synthetase due to increased enzyme catalytic rate.
Academic Article Diagnostic evaluation of phosphoribosylpyrophosphate synthetase activities in hemolysates.
Academic Article Purine overproduction in man associated with increased phosphoribosylpyrophosphate synthetase activity.
Academic Article Evaluation of the role of 5-phosphoribosyl-alpha-1-pyrophosphate synthetase in congenital hyperuricemia and gout: a simple isotopic assay and an activity stain for the enzyme.
Academic Article Patterns of phosphoribosylpyrophosphate and ribose-5-phosphate concentration and generation in fibroblasts from patients with gout and purine overproduction.
Academic Article Fibroblast phosphoribosylpyrophosphate and ribose-5-phosphate concentration and generation in gout with purine overproduction.
Academic Article Efficacy and Safety of Febuxostat Extended and Immediate Release in Patients With Gout and Renal Impairment: A Phase III Placebo-Controlled Study.
Academic Article Evaluation of the Relationship Between Serum Urate Levels, Clinical Manifestations of Gout, and Death From Cardiovascular Causes in Patients Receiving Febuxostat or Allopurinol in an Outcomes Trial.
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