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Ober, Carole
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overview
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The research goals of my laboratory are to parse the roles of genetic variation and environmental exposures in the development of asthma and allergic diseases using genetic, transcriptomic and epigenomic markers and integrated omic and systems level analyses. We focus our studies on freshly isolated (ex vivo) blood and airway cells and in vitro cell culture models of gene-environment interactions. Our studies are in diverse U.S. populations of children and adults who have been followed longitudinally and have detailed phenotypes and environmental assessments.
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