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One or more keywords matched the following items that are connected to Storb, Ursula
Item TypeName
Concept Bone Marrow Cells
Concept Antibody-Producing Cells
Concept B-Lymphocytes
Concept Clone Cells
Concept Hematopoietic Stem Cells
Concept Germ Cells
Concept Plasma Cells
Concept Hybrid Cells
Concept Receptors, Antigen, B-Cell
Concept Gene Rearrangement, B-Lymphocyte
Concept Leukemia, B-Cell
Concept Stem Cells
Concept Tumor Cells, Cultured
Concept B-Lymphocyte Subsets
Concept 3T3 Cells
Concept Gene Rearrangement, B-Lymphocyte, Heavy Chain
Concept Gene Rearrangement, B-Lymphocyte, Light Chain
Concept Dendritic Cells, Follicular
Concept Lymphoma, B-Cell
Concept Cells, Cultured
Concept Lymphocytes
Concept T-Lymphocytes
Academic Article Lymphocyte development.
Academic Article Influence of CpG methylation and target spacing on V(D)J recombination in a transgenic substrate.
Academic Article Somatic hypermutation of immunoglobulin genes is linked to transcription initiation.
Academic Article N region diversity of a transgenic substrate in fetal and adult lymphoid cells.
Academic Article Somatic hypermutation of a lambda 2 transgene under the control of the lambda enhancer or the heavy chain intron enhancer.
Academic Article Identification and characterization of the murine Rag1 promoter.
Academic Article Progress in understanding the mechanism and consequences of somatic hypermutation.
Academic Article Gamma 2b provides only some of the signals normally given via mu in B cell development.
Academic Article B lymphocytes of xeroderma pigmentosum or Cockayne syndrome patients with inherited defects in nucleotide excision repair are fully capable of somatic hypermutation of immunoglobulin genes.
Academic Article The composition of coding joints formed in V(D)J recombination is strongly affected by the nucleotide sequence of the coding ends and their relationship to the recombination signal sequences.
Academic Article Somatic hypermutation of immunoglobulin genes is linked to transcription.
Academic Article Mef2 proteins, required for muscle differentiation, bind an essential site in the Ig lambda enhancer.
Academic Article An efficient method for high-fidelity BAC/PAC retrofitting with a selectable marker for mammalian cell transfection.
Academic Article Somatic hypermutation of immunoglobulin and non-immunoglobulin genes.
Academic Article Mutation of BCL-6 gene in normal B cells by the process of somatic hypermutation of Ig genes.
Academic Article Hypomethylation is necessary but not sufficient for V(D)J recombination within a transgenic substrate.
Academic Article The TATA binding protein, c-Myc and survivin genes are not somatically hypermutated, while Ig and BCL6 genes are hypermutated in human memory B cells.
Academic Article Insertion of phosphoglycerine kinase (PGK)-neo 5' of Jlambda1 dramatically enhances VJlambda1 rearrangement.
Academic Article Signal joint formation is inhibited in murine scid preB cells and fibroblasts in substrates with homopolymeric coding ends.
Academic Article A point mutation in the constant region of Ig lambda1 prevents normal B cell development due to defective BCR signaling.
Academic Article Two conserved essential motifs of the murine immunoglobulin lambda enhancers bind B-cell-specific factors.
Academic Article The E box motif CAGGTG enhances somatic hypermutation without enhancing transcription.
Academic Article Ig gene somatic hypermutation in mice defective for DNA polymerase delta proofreading.
Academic Article Immunology. Autoreactive B cells migrate into T cell territory.
Academic Article Delay of early B-lymphocyte development by gamma 2b immunoglobulin transgene: effect on differentiation-specific molecules.
Academic Article Scarcity of lambda 1 B cells in mice with a single point mutation in C lambda 1 is due to a low BCR signal caused by misfolded lambda 1 light chain.
Academic Article The published data.
Academic Article Factors affecting the rearrangement efficiency of an Ig test gene.
Academic Article Expression of AID transgene is regulated in activated B cells but not in resting B cells and kidney.
Academic Article A novel enhancer in the immunoglobulin lambda locus is duplicated and functionally independent of NF kappa B.
Academic Article Differential splicing of thymosin beta 4 mRNA.
Academic Article Transgenic mice with mu and kappa genes encoding antiphosphorylcholine antibodies.
Academic Article Brca1 in immunoglobulin gene conversion and somatic hypermutation.
Academic Article Expression of immunoglobulin and globin genes in B and T lymphocytes and other cells.
Academic Article Antibodies of different immunoglobulin classes released by single cells.
Academic Article The switch region associated with immunoglobulin C mu genes is DNase I hypersensitive in T lymphocytes.
Academic Article Asymmetric processing of coding ends and the effect of coding end nucleotide composition on V(D)J recombination.
Academic Article Cloning of a gamma 2b gene encoding anti-Pseudomonas aeruginosa H chains and its introduction into the germ line of mice.
Academic Article Alteration of the B cell surface phenotype, immune response to phosphocholine and the B cell repertoire in M167 mu plus kappa transgenic mice.
Academic Article Elevated PC responsive B cells and anti-PC antibody production in transgenic mice harboring anti-PC immunoglobulin genes.
Academic Article Antibody production by host cells in x-irradiated recipients of allogeneic spleen cells.
Academic Article Allelic exclusion and control of endogenous immunoglobulin gene rearrangement in kappa transgenic mice.
Academic Article Strain-specific transgene methylation occurs early in mouse development and can be recapitulated in embryonic stem cells.
Academic Article Kinetics of mouse spleen cell populations during the immune response.
Academic Article Ig lambda-producing B cells do not show feedback inhibition of gene rearrangement.
Academic Article Direct demonstration of immunoglobulin kappa chain RNA in thymus T cells by in situ hybridization.
Academic Article Sequences related to immunoglobulin kappa chain messenger RNA in T cells.
Academic Article Immunoglobulin gene 'remnant' DNA--implications for antibody gene recombination.
Academic Article Nucleosome stability dramatically impacts the targeting of somatic hypermutation.
Academic Article Gamma 2b transgenic mice as a model for the role of immunoglobulins in B cell development.
Academic Article Pip, a novel IRF family member, is a lymphoid-specific, PU.1-dependent transcriptional activator.
Academic Article lambda 5, but not mu, is required for B cell maturation in a unique gamma 2b transgenic mouse line.
Academic Article Expression, allelic exclusion and somatic mutation of mouse immunoglobulin kappa genes.
Academic Article Transgenic mice with immunoglobulin genes.
Academic Article Immunoglobulin messenger RNAs of T lymphocytes.
Academic Article Fusion of a scid pre-B cells with a wild type (myeloma) B cell results in correct rearrangement of a V(D)J recombination substrate.
Academic Article Lymphocyte development.
Academic Article Antibody-carrying cells in the immune response 1. Identification of "rosette"-forming cells by light microscopy.
Academic Article Immunoglobulin mu- and gamma-ribonucleic acid sequences in thymocytes and splenocytes from normal and hyperimmune mice.
Academic Article Myeloma with multiple rearranged immunoglobulin kappa genes: only one kappa gene codes for kappa chains.
Academic Article RNA sequences homologous to the 3' portion of immunoglobulin alpha-chain mRNA in thymus-derived lymphocytes.
Academic Article Expression of lambda and kappa genes can occur in all B cells and is initiated around the same pre-B-cell developmental stage.
Academic Article Immunoglobulin gamma 2b transgenes inhibit heavy chain gene rearrangement, but cannot promote B cell development.
Academic Article Attracting AID to targets of somatic hypermutation.
Academic Article Ultrastructure of rosette-forming cells in the mouse during the antibody response.
Academic Article Rearranged and germline immunoglobulin kappa genes: different states of DNase I sensitivity of constant kappa genes in immunocompetent and nonimmune cells.
Academic Article Methylation patterns of immunoglobulin genes in lymphoid cells: correlation of expression and differentiation with undermethylation.
Academic Article Pip, a lymphoid-restricted IRF, contains a regulatory domain that is important for autoinhibition and ternary complex formation with the Ets factor PU.1.
Academic Article Crossing the SJL lambda locus into kappa-knockout mice reveals a dysfunction of the lambda 1-containing immunoglobulin receptor in B cell differentiation.
Academic Article Different mismatch repair deficiencies all have the same effects on somatic hypermutation: intact primary mechanism accompanied by secondary modifications.
Academic Article The C(H)1 and transmembrane domains of mu in the context of a gamma2b transgene do not suffice to promote B cell maturation.
Academic Article The transcription factor Spi-B is not required for somatic hypermutation.
Academic Article Steps in the generation of autoantibodies.
Academic Article DNA methylation precedes chromatin modifications under the influence of the strain-specific modifier Ssm1.
Academic Article Precursors of both conventional and Ly-1 B cells can escape feedback inhibition of Ig gene rearrangement.
Academic Article The very 5' end and the constant region of Ig genes are spared from somatic mutation because AID does not access these regions.
Academic Article Inhibition of immunoglobulin gene rearrangement by the expression of a lambda 2 transgene.
Academic Article Expression of immunoglobulin genes in transgenic mice and transfected cells.
Academic Article High-frequency deletional rearrangement of immunoglobulin kappa gene segments introduced into a pre-B-cell line.
Academic Article Feedback inhibition of immunoglobulin gene rearrangement by membrane mu, but not by secreted mu heavy chains.
Academic Article B cells expressing Ig transgenes respond to a T-dependent antigen only in the presence of Ia-compatible T cells.
Academic Article Pre-B cells in kappa-transgenic mice.
Academic Article Coexistence of 19S and 7S hemolysins in splenic foci.
Academic Article Immunoglobulin gene rearrangements in hybridoma cells.
Academic Article High expression of cloned immunoglobulin kappa gene in transgenic mice is restricted to B lymphocytes.
Academic Article Immunoglobulin synthesis by T cells: quantitative and qualitative aspects.
Academic Article Antibody-carrying cells in the immune response II. Ultrastructure of "rosette"-forming cells.
Academic Article Changes in RNA polymerase II progression influence somatic hypermutation of Ig-related genes by AID.
Academic Article Influence of metabolic inhibitors on the capacity of spleen cells to form hemolytic plaques and rosettes.
Academic Article Why does somatic hypermutation by AID require transcription of its target genes?
Academic Article Delayed hypersensitivity in vitro.
Academic Article Ssm1b expression and function in germ cells of adult mice and in early embryos.
Concept Embryonic Germ Cells
Grant CONTROL OF IMMUNOGLOBULIN SYNTHESIS
Grant EXPRESSION OF IMMUNOGLOBULIN GENES IN TRANSGENIC MICE
Grant T LYMPHOCYTE SPECIFIC GENES
Grant Mechanism of Immunoglobulin Hypermutation
Grant AID in somatic mutation of immunoglobulin genes
Grant Immunoglobulin Somatic Mutation
Grant EXPRESSION OF IMMUNOGLOBULIN GENES
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  • B Lymphocytes