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Influence of CpG methylation and target spacing on V(D)J recombination in a transgenic substrate.
Identification and characterization of the murine Rag1 promoter.
The inactivation of the XP-C gene does not affect somatic hypermutation or class switch recombination of immunoglobulin genes.
The composition of coding joints formed in V(D)J recombination is strongly affected by the nucleotide sequence of the coding ends and their relationship to the recombination signal sequences.
An efficient method for high-fidelity BAC/PAC retrofitting with a selectable marker for mammalian cell transfection.
Hypomethylation is necessary but not sufficient for V(D)J recombination within a transgenic substrate.
Signal joint formation is inhibited in murine scid preB cells and fibroblasts in substrates with homopolymeric coding ends.
A novel cytidine deaminase affects antibody diversity.
A point mutation in the constant region of Ig lambda1 prevents normal B cell development due to defective BCR signaling.
Ig gene somatic hypermutation in mice defective for DNA polymerase delta proofreading.
Somatic hypermutation and class switch recombination in Msh6(-/-)Ung(-/-) double-knockout mice.
The contested role of uracil DNA glycosylase in immunoglobulin gene diversification.
AID in somatic hypermutation and class switch recombination.
Alkyladenine DNA glycosylase (Aag) in somatic hypermutation and class switch recombination.
Transgenic mice with mu and kappa genes encoding antiphosphorylcholine antibodies.
Asymmetric processing of coding ends and the effect of coding end nucleotide composition on V(D)J recombination.
Allelic exclusion and control of endogenous immunoglobulin gene rearrangement in kappa transgenic mice.
Structural alterations in J regions of mouse immunoglobulin lambda genes are associated with differential gene expression.
Immunoglobulin gene 'remnant' DNA--implications for antibody gene recombination.
Expression, allelic exclusion and somatic mutation of mouse immunoglobulin kappa genes.
Fusion of a scid pre-B cells with a wild type (myeloma) B cell results in correct rearrangement of a V(D)J recombination substrate.
High-frequency deletional rearrangement of immunoglobulin kappa gene segments introduced into a pre-B-cell line.
Immunoglobulin Somatic Mutation