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Storb, Ursula
One or more keywords matched the following items that are connected to Storb, Ursula
Item TypeName
Concept Transgenes
Academic Article The mechanism of somatic hypermutation studied with transgenic and transfected target genes.
Academic Article Somatic hypermutation of immunoglobulin genes is linked to transcription initiation.
Academic Article Somatic hypermutation of a lambda 2 transgene under the control of the lambda enhancer or the heavy chain intron enhancer.
Academic Article Somatic hypermutation of an artificial test substrate within an Ig kappa transgene.
Academic Article Immunoglobulin transgenes as targets for somatic hypermutation.
Academic Article Cis-acting sequences that affect somatic hypermutation of Ig genes.
Academic Article A hypermutable insert in an immunoglobulin transgene contains hotspots of somatic mutation and sequences predicting highly stable structures in the RNA transcript.
Academic Article A cis-acting element that directs the activity of the murine methylation modifier locus Ssm1.
Academic Article Effects of sequence and structure on the hypermutability of immunoglobulin genes.
Academic Article Mutation pattern of immunoglobulin transgenes is compatible with a model of somatic hypermutation in which targeting of the mutator is linked to the direction of DNA replication.
Academic Article Delay of early B-lymphocyte development by gamma 2b immunoglobulin transgene: effect on differentiation-specific molecules.
Academic Article Scarcity of lambda 1 B cells in mice with a single point mutation in C lambda 1 is due to a low BCR signal caused by misfolded lambda 1 light chain.
Academic Article Expression of AID transgene is regulated in activated B cells but not in resting B cells and kidney.
Academic Article A strain-specific modifier on mouse chromosome 4 controls the methylation of independent transgene loci.
Academic Article Somatic hypermutation of an immunoglobulin transgene in kappa transgenic mice.
Academic Article Analysis of somatic mutations in kappa transgenes.
Academic Article Strain-specific transgene methylation occurs early in mouse development and can be recapitulated in embryonic stem cells.
Academic Article Immunoglobulin gamma 2b transgenes inhibit heavy chain gene rearrangement, but cannot promote B cell development.
Academic Article The bulk chromatin structure of a murine transgene does not vary with its transcriptional or DNA methylation status.
Academic Article Different mismatch repair deficiencies all have the same effects on somatic hypermutation: intact primary mechanism accompanied by secondary modifications.
Academic Article The C(H)1 and transmembrane domains of mu in the context of a gamma2b transgene do not suffice to promote B cell maturation.
Academic Article DNA methylation precedes chromatin modifications under the influence of the strain-specific modifier Ssm1.
Academic Article The very 5' end and the constant region of Ig genes are spared from somatic mutation because AID does not access these regions.
Academic Article Inhibition of immunoglobulin gene rearrangement by the expression of a lambda 2 transgene.
Academic Article B cells expressing Ig transgenes respond to a T-dependent antigen only in the presence of Ia-compatible T cells.
Grant CONTROL OF IMMUNOGLOBULIN SYNTHESIS
Grant EXPRESSION OF IMMUNOGLOBULIN GENES IN TRANSGENIC MICE
Grant MUTATION OF IG GENES
Grant Immunoglobulin Somatic Mutation
Grant Identification of the DNA methylation/chromatin modifier Ssm1
Search Criteria
  • Transgenes