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The University of Chicago

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Crawley, Clayton

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Item Type	Name
Concept	NF-kappa B p50 Subunit
Academic Article	p50 (NF-?B1) is an effector protein in the cytotoxic response to DNA methylation damage.
Academic Article	DNA damage-induced cytotoxicity is mediated by the cooperative interaction of phospho-NF-?B p50 and a single nucleotide in the ?B-site.
Academic Article	Nfkb1 is a haploinsufficient DNA damage-specific tumor suppressor.
Academic Article	Loss of Nfkb1 leads to early onset aging.
Academic Article	S-phase-dependent p50/NF-?B1 phosphorylation in response to ATR and replication stress acts to maintain genomic stability.
Academic Article	Decoy Receptor DcR1 Is Induced in a p50/Bcl3-Dependent Manner and Attenuates the Efficacy of Temozolomide.
Academic Article	p50 mono-ubiquitination and interaction with BARD1 regulates cell cycle progression and maintains genome stability.

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NF kappa B p50 Subunit