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One or more keywords matched the following items that are connected to Piccirilli, Joseph A.
Item TypeName
Concept Biocatalysis
Academic Article The ribotoxin restrictocin recognizes its RNA substrate by selective engagement of active site residues.
Academic Article Nascent peptide in the ribosome exit tunnel affects functional properties of the A-site of the peptidyl transferase center.
Academic Article Arginine as a general acid catalyst in serine recombinase-mediated DNA cleavage.
Academic Article Altered (transition) states: mechanisms of solution and enzyme catalyzed RNA 2'-O-transphosphorylation.
Academic Article Experimental and computational analysis of the transition state for ribonuclease A-catalyzed RNA 2'-O-transphosphorylation.
Academic Article Enzyme transition states from theory and experiment.
Academic Article Integration of kinetic isotope effect analyses to elucidate ribonuclease mechanism.
Academic Article Effect of Zn2+ binding and enzyme active site on the transition state for RNA 2'-O-transphosphorylation interpreted through kinetic isotope effects.
Academic Article Structural Basis for Substrate Helix Remodeling and Cleavage Loop Activation in the Varkud Satellite Ribozyme.
Academic Article Kinetic Isotope Effect Analysis of RNA 2'-O-Transphosphorylation.
Academic Article Confluence of theory and experiment reveals the catalytic mechanism of the Varkud satellite ribozyme.
Academic Article The Positively Charged Active Site of the Bacterial Toxin RelE Causes a Large Shift in the General Base pKa.
Academic Article The Varkud Satellite Ribozyme: A Thirty-Year Journey through Biochemistry, Crystallography, and Computation.
Academic Article The hammerhead self-cleaving motif as a precursor to complex endonucleolytic ribozymes.
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  • Biocatalysis