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Piccirilli, Joseph A.

One or more keywords matched the following items that are connected to Piccirilli, Joseph A.

Item Type	Name
Concept	Oligonucleotides
Concept	Phosphorothioate Oligonucleotides
Academic Article	Redesigning nucleic acids.
Academic Article	The tetrahymena ribozyme cleaves a 5'-methylene phosphonate monoester approximately 10(2)-fold faster than a normal phosphate diester: implications for enzyme catalysis of phosphoryl transfer reactions.
Academic Article	Synthesis of 2'-C-difluoromethylribonucleosides and their enzymatic incorporation into oligonucleotides.
Academic Article	Improved synthesis of 2'-amino-2'-deoxyguanosine and its phosphoramidite.
Academic Article	A systematic, ligation-based approach to study RNA modifications.
Academic Article	Efficient synthesis of [2'-18O]uridine and its incorporation into oligonucleotides: a new tool for mechanistic study of nucleotidyl transfer reactions by isotope effect analysis.
Academic Article	Efficient chemical synthesis of AppDNA by adenylation of immobilized DNA-5'-monophosphate.
Academic Article	Nucleobase-mediated general acid-base catalysis in the Varkud satellite ribozyme.
Academic Article	Sin resolvase catalytic activity and oligomerization state are tightly coupled.
Academic Article	The mechanism of RNA strand scission: an experimental measure of the Brønsted coefficient, beta nuc.
Academic Article	A general and efficient approach for the construction of RNA oligonucleotides containing a 5'-phosphorothiolate linkage.
Academic Article	Automated solid-phase synthesis of RNA oligonucleotides containing a nonbridging phosphorodithioate linkage via phosphorothioamidites.
Academic Article	Origin of life. RNA seeks its maker.
Academic Article	Separation of RNA phosphorothioate oligonucleotides by HPLC.
Academic Article	Synthesis, properties, and applications of oligonucleotides containing an RNA dinucleotide phosphorothiolate linkage.
Academic Article	Synthesis of 2'-O-photocaged ribonucleoside phosphoramidites.
Academic Article	2'-C-Branched Ribonucleosides: Synthesis of the Phosphoramidite Derivatives of 2'-C-beta-Methylcytidine and Their Incorporation into Oligonucleotides.
Academic Article	Synthesis and Characterization of Oligonucleotides Containing 2'-S,3'-O-Cyclic Phosphorothiolate Termini.
Academic Article	Incorporation of 2'-Deoxy-2'-mercaptocytidine into Oligonucleotides via Phosphoramidite Chemistry.
Academic Article	Evidence That Nucleophile Deprotonation Exceeds Bond Formation in the HDV Ribozyme Transition State.
Academic Article	Branched kissing loops for the construction of diverse RNA homooligomeric nanostructures.

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Oligonucleotides