Item Type | Name |
Concept
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Antigen-Antibody Complex
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Concept
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Antigen-Presenting Cells
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Concept
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Gene Rearrangement, beta-Chain T-Cell Antigen Receptor
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Concept
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HLA-A2 Antigen
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Concept
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Receptors, Antigen, T-Cell, gamma-delta
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Concept
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T-Cell Antigen Receptor Specificity
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Concept
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Receptors, Antigen, T-Cell, alpha-beta
|
Concept
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Antigen Presentation
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Concept
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B7-1 Antigen
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Concept
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B7-H1 Antigen
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Concept
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CTLA-4 Antigen
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Concept
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CD11b Antigen
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Concept
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Antigen-Antibody Reactions
|
Concept
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Carcinoembryonic Antigen
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Concept
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Receptors, Antigen, T-Cell
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Academic Article
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A tumor escape variant that has lost one major histocompatibility complex class I restriction element induces specific CD8+ T cells to an antigen that no longer serves as a target.
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Academic Article
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DNA sequence analysis of T-cell receptor genes reveals an oligoclonal T-cell response to a tumor with multiple target antigens.
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Academic Article
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Antigenic cancer cells grow progressively in immune hosts without evidence for T cell exhaustion or systemic anergy.
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Academic Article
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Immunodominance deters the response to other tumor antigens thereby favoring escape: prevention by vaccination with tumor variants selected with cloned cytolytic T cells in vitro.
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Academic Article
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The immunodominant antigen of an ultraviolet-induced regressor tumor is generated by a somatic point mutation in the DEAD box helicase p68.
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Academic Article
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Establishment of an HLA-A*0201 human papillomavirus type 16 tumor model to determine the efficacy of vaccination strategies in HLA-A*0201 transgenic mice.
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Academic Article
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Complementary role of CD4+ T cells and secondary lymphoid tissues for cross-presentation of tumor antigen to CD8+ T cells.
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Academic Article
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Tumor immunity meets autoimmunity: antigen levels and dendritic cell maturation.
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Academic Article
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A new murine tumor model for studying HLA-A2-restricted anti-tumor immunity.
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Academic Article
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The terminology issue for myeloid-derived suppressor cells.
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Academic Article
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Mechanism of tumor rejection in anti-CD3 monoclonal antibody-treated mice.
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Academic Article
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Induced sensitization of tumor stroma leads to eradication of established cancer by T cells.
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Academic Article
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Ribosomal versus non-ribosomal cellular antigens: factors determining efficiency of indirect presentation to CD4+ T cells.
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Academic Article
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A mutant chaperone converts a wild-type protein into a tumor-specific antigen.
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Academic Article
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Antibody recognition of a unique tumor-specific glycopeptide antigen.
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Academic Article
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Long-term persistence of CD4(+) but rapid disappearance of CD8(+) T cells expressing an MHC class I-restricted TCR of nanomolar affinity.
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Academic Article
|
Cancer. Quo vadis, specificity?
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Academic Article
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Progression of cancer from indolent to aggressive despite antigen retention and increased expression of interferon-gamma inducible genes.
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Academic Article
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IFN-gamma- and TNF-dependent bystander eradication of antigen-loss variants in established mouse cancers.
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Academic Article
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Rapid destruction of the tumor microenvironment by CTLs recognizing cancer-specific antigens cross-presented by stromal cells.
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Academic Article
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Antigenic cancer cells that escape immune destruction are stimulated by host cells.
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Academic Article
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Recurrence of intracranial tumors following adoptive T cell therapy can be prevented by direct and indirect killing aided by high levels of tumor antigen cross-presented on stromal cells.
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Academic Article
|
Floxed reporter genes: Flow-cytometric selection of clonable cells expressing high levels of a target gene after tamoxifen-regulated Cre-loxP recombination.
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Academic Article
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A unique tumor antigen produced by a single amino acid substitution.
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Academic Article
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Identification of a gene encoding a tumor-specific antigen that causes tumor rejection.
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Academic Article
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Specific detection of carcinoembryonic antigen-expressing tumor cells in bone marrow aspirates by polymerase chain reaction.
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Academic Article
|
[CA 12-5 in cancer of the digestive tract. A comparison with CA 19-9 and CEA in cancer of the pancreas and colon].
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Academic Article
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Animals bearing malignant grafts reject normal grafts that express through gene transfer the same antigen.
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Academic Article
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Increasing tumor antigen expression overcomes "ignorance" to solid tumors via crosspresentation by bone marrow-derived stromal cells.
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Academic Article
|
Bystander elimination of antigen loss variants in established tumors.
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Academic Article
|
Major histocompatibility complex class I and unique antigen expression by murine tumors that escaped from CD8+ T-cell-dependent surveillance.
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Academic Article
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In vivo administration of anti-CD3 prevents malignant progressor tumor growth.
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Academic Article
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Tumors with reduced expression of a cytotoxic T lymphocyte recognized antigen lack immunogenicity but retain sensitivity to lysis by cytotoxic T lymphocytes.
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Academic Article
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IL-15 in tumor microenvironment causes rejection of large established tumors by T cells in a noncognate T cell receptor-dependent manner.
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Academic Article
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Relapse or eradication of cancer is predicted by peptide-major histocompatibility complex affinity.
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Academic Article
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MHC-class I-restricted CD4 T cells: a nanomolar affinity TCR has improved anti-tumor efficacy in vivo compared to the micromolar wild-type TCR.
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Academic Article
|
Design and characterization of a protein superagonist of IL-15 fused with IL-15Ra and a high-affinity T cell receptor.
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Academic Article
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Adoptively transferred immune T cells eradicate established tumors despite cancer-induced immune suppression.
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Academic Article
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Dual blockade of PD-1 and CTLA-4 combined with tumor vaccine effectively restores T-cell rejection function in tumors--letter.
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Academic Article
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Antigen-specific bacterial vaccine combined with anti-PD-L1 rescues dysfunctional endogenous T cells to reject long-established cancer.
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Academic Article
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Targeting cancer-specific mutations by T cell receptor gene therapy.
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Academic Article
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Eradication of Large Solid Tumors by Gene Therapy with a T-Cell Receptor Targeting a Single Cancer-Specific Point Mutation.
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Academic Article
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Engineered CAR T Cells Targeting the Cancer-Associated Tn-Glycoform of the Membrane Mucin MUC1 Control Adenocarcinoma.
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Academic Article
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A sensitivity scale for targeting T cells with chimeric antigen receptors (CARs) and bispecific T-cell Engagers (BiTEs).
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Academic Article
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Transfer of Allogeneic CD4+ T Cells Rescues CD8+ T Cells in Anti-PD-L1-Resistant Tumors Leading to Tumor Eradication.
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Academic Article
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TCR-pMHC bond conformation controls TCR ligand discrimination.
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Academic Article
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Neoadjuvant PD-1 Immune Checkpoint Blockade Reverses Functional Immunodominance among Tumor Antigen-Specific T Cells.
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Academic Article
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Multiple cancer-specific antigens are targeted by a chimeric antigen receptor on a single cancer cell.
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Academic Article
|
Multiple cancer-specific antigens are targeted by a chimeric antigen receptor on a single cancer cell.
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Academic Article
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Impact of TCR Diversity on the Development of Transplanted or Chemically Induced Tumors.
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Academic Article
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Structure-guided engineering of the affinity and specificity of CARs against Tn-glycopeptides.
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Academic Article
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Antigen-Multimers: Specific, Sensitive, Precise, and Multifunctional High-Avidity CAR-Staining Reagents.
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Concept
|
Histocompatibility Antigen H-2D
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Grant
|
TRANSFORMING GENES AND IMMUNOLOGICAL TUMOR REGRESSION
|
Grant
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Manipulation of Tumor Specific Immunity
|
Grant
|
IMMUNITY AND CANCER
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Grant
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MANIPULATION OF TUMOR-SPECIFIC IMMUNITY
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Grant
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Immunology of Unique Tumor Specific Antigens
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Academic Article
|
Single CAR-T cell treatment controls disseminated ovarian cancer in a syngeneic mouse model.
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Academic Article
|
One CD4+TCR and One CD8+TCR Targeting Autochthonous Neoantigens Are Essential and Sufficient for Tumor Eradication.
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