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Schreiber, Hans

One or more keywords matched the following items that are connected to Schreiber, Hans

Item Type	Name
Concept	Antigens, Differentiation, T-Lymphocyte
Concept	B-Lymphocytes
Concept	Lymphocyte Depletion
Concept	Lymphocyte Culture Test, Mixed
Concept	CD4-Positive T-Lymphocytes
Concept	Lymphocytes, Tumor-Infiltrating
Concept	T-Lymphocyte Subsets
Concept	CD8-Positive T-Lymphocytes
Concept	Lymphocyte Count
Concept	Epitopes, T-Lymphocyte
Concept	T-Lymphocytes, Cytotoxic
Concept	T-Lymphocytes, Regulatory
Concept	Lymphocyte Activation
Concept	T-Lymphocytes
Academic Article	A tumor escape variant that has lost one major histocompatibility complex class I restriction element induces specific CD8+ T cells to an antigen that no longer serves as a target.
Academic Article	DNA sequence analysis of T-cell receptor genes reveals an oligoclonal T-cell response to a tumor with multiple target antigens.
Academic Article	Genetically engineered vaccines. Comparison of active versus passive immunotherapy against solid tumors.
Academic Article	Antigenic cancer cells grow progressively in immune hosts without evidence for T cell exhaustion or systemic anergy.
Academic Article	Immunodominance deters the response to other tumor antigens thereby favoring escape: prevention by vaccination with tumor variants selected with cloned cytolytic T cells in vitro.
Academic Article	The immunodominant antigen of an ultraviolet-induced regressor tumor is generated by a somatic point mutation in the DEAD box helicase p68.
Academic Article	Unique tumor antigens redefined as mutant tumor-specific antigens.
Academic Article	Tumor cells induce cytolytic T cells to a single immunodominant mutant peptide.
Academic Article	Immunological enhancement of primary tumor development and its prevention.
Academic Article	Tracking the common ancestry of antigenically distinct cancer variants.
Academic Article	Pharmacokinetic differences between a T cell-tolerizing and a T cell-activating peptide.
Academic Article	Point mutation in essential genes with loss or mutation of the second allele: relevance to the retention of tumor-specific antigens.
Academic Article	Enhanced eradication of local and distant tumors by genetically produced interleukin-12 and radiation.
Academic Article	Role of TGF-beta in immune-evasion of cancer.
Academic Article	MHC class I restricted T cells and immune surveillance against transplanted ultraviolet light-induced tumors.
Academic Article	C-kit+ FcR+ myelocytes are increased in cancer and prevent the proliferation of fully cytolytic T cells in the presence of immune serum.
Academic Article	Complementary role of CD4+ T cells and secondary lymphoid tissues for cross-presentation of tumor antigen to CD8+ T cells.
Academic Article	Priming of naive T cells inside tumors leads to eradication of established tumors.
Academic Article	Genetic changes occurring in established tumors rapidly stimulate new antibody responses.
Academic Article	A highly immunogenic tumor transfected with a murine transforming growth factor type beta 1 cDNA escapes immune surveillance.
Academic Article	Intratumor depletion of CD4+ cells unmasks tumor immunogenicity leading to the rejection of late-stage tumors.
Academic Article	Long-term suppression of tumor growth by TNF requires a Stat1- and IFN regulatory factor 1-dependent IFN-gamma pathway but not IL-12 or IL-18.
Academic Article	Mechanism of tumor rejection in anti-CD3 monoclonal antibody-treated mice.
Academic Article	Inflammation as a tumor promoter in cancer induction.
Academic Article	Specificity in cancer immunotherapy.
Academic Article	Induced sensitization of tumor stroma leads to eradication of established cancer by T cells.
Academic Article	Ribosomal versus non-ribosomal cellular antigens: factors determining efficiency of indirect presentation to CD4+ T cells.
Academic Article	Long-term persistence of CD4(+) but rapid disappearance of CD8(+) T cells expressing an MHC class I-restricted TCR of nanomolar affinity.
Academic Article	Densely granulated murine NK cells eradicate large solid tumors.
Academic Article	Cancer. Quo vadis, specificity?
Academic Article	Highly immunogenic regressor tumor cells can prevent development of postsurgical tumor immunity.
Academic Article	Progression of cancer from indolent to aggressive despite antigen retention and increased expression of interferon-gamma inducible genes.
Academic Article	IFN-gamma- and TNF-dependent bystander eradication of antigen-loss variants in established mouse cancers.
Academic Article	Rapid destruction of the tumor microenvironment by CTLs recognizing cancer-specific antigens cross-presented by stromal cells.
Academic Article	Long-term inhibition of tumor growth by tumor necrosis factor in the absence of cachexia or T-cell immunity.
Academic Article	Antigenic cancer cells that escape immune destruction are stimulated by host cells.
Academic Article	Recurrence of intracranial tumors following adoptive T cell therapy can be prevented by direct and indirect killing aided by high levels of tumor antigen cross-presented on stromal cells.
Academic Article	CD40 ligation restores cytolytic T lymphocyte response and eliminates fibrosarcoma in the peritoneum of mice lacking CD4+ T cells.
Academic Article	Spleen cells from young but not old immunized mice eradicate large established cancers.
Academic Article	A unique tumor antigen produced by a single amino acid substitution.
Academic Article	Synergy between T-cell immunity and inhibition of paracrine stimulation causes tumor rejection.
Academic Article	Cancer. Awakening immunity.
Academic Article	Tumor antigens defined by cloned immunological probes are highly polymorphic and are not detected on autologous normal cells.
Academic Article	CD4+ and B lymphocytes in transplantation immunity. II. Augmented rejection of tumor allografts by mice lacking B cells.
Academic Article	Targeting the primary tumor to generate CTL for the effective eradication of spontaneous metastases.
Academic Article	CD4-positive and B lymphocytes in transplantation immunity. I. Promotion of tumor allograft rejection through elimination of CD4-positive lymphocytes.
Academic Article	Equilibrium between host and cancer caused by effector T cells killing tumor stroma.
Academic Article	CD4(+) T cells eliminate MHC class II-negative cancer cells in vivo by indirect effects of IFN-gamma.
Academic Article	Bystander elimination of antigen loss variants in established tumors.
Academic Article	Major histocompatibility complex class I and unique antigen expression by murine tumors that escaped from CD8+ T-cell-dependent surveillance.
Academic Article	Bystander killing of cancer requires the cooperation of CD4(+) and CD8(+) T cells during the effector phase.
Academic Article	In vivo administration of anti-CD3 prevents malignant progressor tumor growth.
Academic Article	Tumors with reduced expression of a cytotoxic T lymphocyte recognized antigen lack immunogenicity but retain sensitivity to lysis by cytotoxic T lymphocytes.
Academic Article	IL-15 in tumor microenvironment causes rejection of large established tumors by T cells in a noncognate T cell receptor-dependent manner.
Academic Article	Relapse or eradication of cancer is predicted by peptide-major histocompatibility complex affinity.
Academic Article	MHC-class I-restricted CD4 T cells: a nanomolar affinity TCR has improved anti-tumor efficacy in vivo compared to the micromolar wild-type TCR.
Academic Article	Innate and adaptive immune cells in the tumor microenvironment.
Academic Article	Adoptively transferred immune T cells eradicate established tumors despite cancer-induced immune suppression.
Academic Article	Dual blockade of PD-1 and CTLA-4 combined with tumor vaccine effectively restores T-cell rejection function in tumors--letter.
Academic Article	Antigen-specific bacterial vaccine combined with anti-PD-L1 rescues dysfunctional endogenous T cells to reject long-established cancer.
Academic Article	Targeting cancer-specific mutations by T cell receptor gene therapy.
Academic Article	Eradication of Large Solid Tumors by Gene Therapy with a T-Cell Receptor Targeting a Single Cancer-Specific Point Mutation.
Academic Article	Engineered CAR T Cells Targeting the Cancer-Associated Tn-Glycoform of the Membrane Mucin MUC1 Control Adenocarcinoma.
Academic Article	Transfer of Allogeneic CD4+ T Cells Rescues CD8+ T Cells in Anti-PD-L1-Resistant Tumors Leading to Tumor Eradication.
Academic Article	TCR-pMHC bond conformation controls TCR ligand discrimination.
Academic Article	Neoadjuvant PD-1 Immune Checkpoint Blockade Reverses Functional Immunodominance among Tumor Antigen-Specific T Cells.
Academic Article	Impact of TCR Diversity on the Development of Transplanted or Chemically Induced Tumors.
Academic Article	Automated cell cluster analysis provides insight into multi-cell-type interactions between immune cells and their targets.
Academic Article	Structure-guided engineering of the affinity and specificity of CARs against Tn-glycopeptides.
Grant	Manipulation of Tumor Specific Immunity
Academic Article	Single CAR-T cell treatment controls disseminated ovarian cancer in a syngeneic mouse model.
Academic Article	One CD4+TCR and One CD8+TCR Targeting Autochthonous Neoantigens Are Essential and Sufficient for Tumor Eradication.

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