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Salgia, Ravi
One or more keywords matched the following items that are connected to Salgia, Ravi
Item TypeName
Concept Blood Cells
Concept Bone Marrow Cells
Concept Carcinoma, Squamous Cell
Concept Cell Communication
Concept Cell Line, Transformed
Concept Cell Membrane Permeability
Concept Cell Count
Concept Cell Differentiation
Concept Cell Movement
Concept Cell Nucleus
Concept Carcinoma, Renal Cell
Concept Carcinoma, Non-Small-Cell Lung
Concept Cell Membrane
Concept Cell Division
Concept Cell Adhesion
Concept Cell Cycle
Concept Cell Transformation, Neoplastic
Concept Epithelial Cells
Concept Hematopoietic Stem Cells
Concept Neoplastic Cells, Circulating
Concept Receptors, Cell Surface
Concept Receptors, Antigen, B-Cell
Concept Stem Cells
Concept CHO Cells
Concept Leukemia, Lymphocytic, Chronic, B-Cell
Concept Sarcoma, Small Cell
Concept Cell Culture Techniques
Concept Tumor Cells, Cultured
Concept Cell Adhesion Molecules
Concept 3T3 Cells
Concept Hematopoietic Cell Growth Factors
Concept Cell Transplantation
Concept Cell Proliferation
Concept Neoplasms, Squamous Cell
Concept Jurkat Cells
Concept Single-Cell Analysis
Concept Carcinoma, Large Cell
Concept Carcinoma, Small Cell
Concept COS Cells
Concept Cell Growth Processes
Concept Cell Cycle Proteins
Concept Stem Cell Factor
Concept Active Transport, Cell Nucleus
Concept Platelet Endothelial Cell Adhesion Molecule-1
Concept HEK293 Cells
Concept Human Umbilical Vein Endothelial Cells
Concept Precursor B-Cell Lymphoblastic Leukemia-Lymphoma
Concept Small Cell Lung Carcinoma
Concept Cell Death
Concept Lymphoma, Large B-Cell, Diffuse
Concept Cell Polarity
Concept Precursor Cell Lymphoblastic Leukemia-Lymphoma
Concept K562 Cells
Concept Cell Cycle Checkpoints
Concept G1 Phase Cell Cycle Checkpoints
Concept Endothelial Cells
Concept Programmed Cell Death 1 Receptor
Concept Cell Line, Tumor
Concept Cell Size
Concept Cell Shape
Concept Cell Line
Concept Cell Physiological Phenomena
Concept Cell Survival
Concept Cells, Cultured
Concept Neoplastic Stem Cells
Concept U937 Cells
Concept Myeloid Cells
Academic Article p210BCR/ABL induces formation of complexes containing focal adhesion proteins and the protooncogene product p120c-Cbl.
Academic Article Interleukin-3 and p210 BCR/ABL activate both unique and overlapping pathways of signal transduction in a factor-dependent myeloid cell line.
Academic Article Steel factor induces tyrosine phosphorylation of CRKL and binding of CRKL to a complex containing c-kit, phosphatidylinositol 3-kinase, and p120(CBL).
Academic Article Activation of hematopoietic growth factor signal transduction pathways by the human oncogene BCR/ABL.
Academic Article p130CAS forms a signaling complex with the adapter protein CRKL in hematopoietic cells transformed by the BCR/ABL oncogene.
Academic Article BCR/ABL induces multiple abnormalities of cytoskeletal function.
Academic Article The related adhesion focal tyrosine kinase forms a complex with paxillin in hematopoietic cells.
Academic Article The phosphatidylinositol polyphosphate 5-phosphatase SHIP and the protein tyrosine phosphatase SHP-2 form a complex in hematopoietic cells which can be regulated by BCR/ABL and growth factors.
Academic Article Involvement of p130(Cas) and p105(HEF1), a novel Cas-like docking protein, in a cytoskeleton-dependent signaling pathway initiated by ligation of integrin or antigen receptor on human B cells.
Academic Article The proto-oncogene product p120CBL and the adaptor proteins CRKL and c-CRK link c-ABL, p190BCR/ABL and p210BCR/ABL to the phosphatidylinositol-3' kinase pathway.
Academic Article The BCR/ABL oncogene alters interaction of the adapter proteins CRKL and CRK with cellular proteins.
Academic Article Tyrosine phosphorylation of the product of the c-cbl protooncogene is [corrected] induced after integrin stimulation.
Academic Article Association of the Cas-like molecule HEF1 with CrkL following integrin and antigen receptor signaling in human B-cells: potential relevance to neoplastic lymphohematopoietic cells.
Academic Article Hematopoietic growth factors signal through the formation of reactive oxygen species.
Academic Article Role of focal adhesion proteins in signal transduction and oncogenesis.
Academic Article Thrombopoietin induces activation of the phosphatidylinositol-3' kinase pathway and formation of a complex containing p85PI3K and the protooncoprotein p120CBL.
Academic Article The bovine papillomavirus E6 protein binds to the LD motif repeats of paxillin and blocks its interaction with vinculin and the focal adhesion kinase.
Academic Article Growth inhibition and modulation of kinase pathways of small cell lung cancer cell lines by the novel tyrosine kinase inhibitor STI 571.
Academic Article Role of serum tumor markers CA 125 and CEA in non-small cell lung cancer.
Academic Article The role of focal adhesion kinase binding in the regulation of tyrosine phosphorylation of paxillin.
Academic Article The BCR/ABL tyrosine kinase induces production of reactive oxygen species in hematopoietic cells.
Academic Article The BCR/ABL oncogene alters the chemotactic response to stromal-derived factor-1alpha.
Academic Article Chemokine receptors CXCR-1/2 activate mitogen-activated protein kinase via the epidermal growth factor receptor in ovarian cancer cells.
Academic Article Molecular abnormalities in lung cancer.
Academic Article Expression of the focal adhesion protein paxillin in lung cancer and its relation to cell motility.
Academic Article Cancer-associated retinopathy in a patient with non-small-cell lung carcinoma.
Academic Article Tyrosine phosphorylation of rasGAP and associated proteins in chronic myelogenous leukemia cell lines.
Academic Article Gemcitabine and vinorelbine in patients with advanced lung cancer: preclinical studies and report of a phase I trial.
Academic Article Vascular endothelial growth factor-induced migration of multiple myeloma cells is associated with beta 1 integrin- and phosphatidylinositol 3-kinase-dependent PKC alpha activation.
Academic Article The noncatalytic domain of protein-tyrosine phosphatase-PEST targets paxillin for dephosphorylation in vivo.
Academic Article A cdc15-like adaptor protein (CD2BP1) interacts with the CD2 cytoplasmic domain and regulates CD2-triggered adhesion.
Academic Article ATP6S1 elicits potent humoral responses associated with immune-mediated tumor destruction.
Academic Article Differential expression and signaling of CBL and CBL-B in BCR/ABL transformed cells.
Academic Article A fragment of paxillin binds the alpha 4 integrin cytoplasmic domain (tail) and selectively inhibits alpha 4-mediated cell migration.
Academic Article Molecular cloning and characterization of human trabeculin-alpha, a giant protein defining a new family of actin-binding proteins.
Academic Article SHIP1, an SH2 domain containing polyinositol-5-phosphatase, regulates migration through two critical tyrosine residues and forms a novel signaling complex with DOK1 and CRKL.
Academic Article BAL is a novel risk-related gene in diffuse large B-cell lymphomas that enhances cellular migration.
Academic Article Regulation of cellular proliferation, cytoskeletal function, and signal transduction through CXCR4 and c-Kit in small cell lung cancer cells.
Academic Article CD2 molecules redistribute to the uropod during T cell scanning: implications for cellular activation and immune surveillance.
Academic Article Role of the cytoskeletal protein paxillin in oncogenesis.
Academic Article Role of the hepatocyte growth factor receptor, c-Met, in oncogenesis and potential for therapeutic inhibition.
Academic Article Vaccination with irradiated autologous tumor cells engineered to secrete granulocyte-macrophage colony-stimulating factor augments antitumor immunity in some patients with metastatic non-small-cell lung carcinoma.
Academic Article Modulation of the c-Met/hepatocyte growth factor pathway in small cell lung cancer.
Academic Article Circulating tumor cells and serum tumor biomarkers in small cell lung cancer.
Academic Article Cell motility, adhesion, homing, and migration assays in the studies of tyrosine kinases.
Academic Article Role of receptor tyrosine kinases in lung cancer.
Academic Article Activated c-Met signals through PI3K with dramatic effects on cytoskeletal functions in small cell lung cancer.
Academic Article c-MET mutational analysis in small cell lung cancer: novel juxtamembrane domain mutations regulating cytoskeletal functions.
Academic Article Fibronectin enhances viability and alters cytoskeletal functions (with effects on the phosphatidylinositol 3-kinase pathway) in small cell lung cancer.
Academic Article 2-methoxyestradiol alters cell motility, migration, and adhesion.
Academic Article Molecular alterations in lung cancer. Impact on prognosis.
Academic Article Small cell lung cancer: from molecular biology to novel therapeutics.
Academic Article Use of temozolomide with other cytotoxic chemotherapy in the treatment of patients with recurrent brain metastases from lung cancer.
Academic Article Targeted molecules in small cell lung cancer.
Academic Article Small-cell cancers, and an unusual reaction to chemotherapy. Case 1. Extrapulmonary small-cell carcinoma arising in the prostate.
Academic Article p53 and Bcl-2 in small cell-lung cancer.
Academic Article Reliable and sensitive identification of occult tumor cells using the improved rare event imaging system.
Academic Article Phase II study of imatinib in patients with small cell lung cancer.
Academic Article A selective small molecule c-MET Inhibitor, PHA665752, cooperates with rapamycin.
Academic Article Modulation of c-Kit/SCF pathway leads to alterations in topoisomerase-I activity in small cell lung cancer.
Academic Article Functional expression and mutations of c-Met and its therapeutic inhibition with SU11274 and small interfering RNA in non-small cell lung cancer.
Academic Article c-Met as a target for human cancer and characterization of inhibitors for therapeutic intervention.
Academic Article Expression of Siva-1 protein or its putative amphipathic helical region enhances cisplatin-induced apoptosis in breast cancer cells: effect of elevated levels of BCL-2.
Academic Article Activation of HGF/c-Met pathway contributes to the reactive oxygen species generation and motility of small cell lung cancer cells.
Academic Article A selective small molecule inhibitor of c-Met, PHA665752, inhibits tumorigenicity and angiogenesis in mouse lung cancer xenografts.
Academic Article Molecular biology of malignant mesothelioma: a review.
Academic Article A review of topoisomerase inhibition in lung cancer.
Academic Article c-Met: structure, functions and potential for therapeutic inhibition.
Academic Article Recent advances in the molecular biology, diagnosis and novel therapies for various small blue cell tumors.
Academic Article PAX5 is expressed in small-cell lung cancer and positively regulates c-Met transcription.
Academic Article MET as a target for treatment of chest tumors.
Academic Article Phase I trial of erlotinib-based multimodality therapy for inoperable stage III non-small cell lung cancer.
Academic Article Activation of the PI3K/mTOR pathway by BCR-ABL contributes to increased production of reactive oxygen species.
Academic Article Protein kinase C beta in malignant pleural mesothelioma.
Academic Article EGFR-targeted therapeutics: focus on SCCHN and NSCLC.
Academic Article Biology and novel therapeutics for neuroendocrine tumors of the lung.
Academic Article Integrin-dependent protein tyrosine phosphorylation is a key regulatory event in collagen-IV-mediated adhesion and proliferation of human lung tumor cell line, Calu-1.
Academic Article The MET receptor tyrosine kinase is a potential novel therapeutic target for head and neck squamous cell carcinoma.
Academic Article Lymphatic vessel density is not associated with lymph node metastasis in non-small cell lung carcinoma.
Academic Article Synergism of EGFR and c-Met pathways, cross-talk and inhibition, in non-small cell lung cancer.
Academic Article The role of ephrins and Eph receptors in cancer.
Academic Article Concerted potent humoral immune responses to autoantigens are associated with tumor destruction and favorable clinical outcomes without autoimmunity.
Academic Article Expression and mutational analysis of MET in human solid cancers.
Academic Article Role of c-Met in cancer: emphasis on lung cancer.
Academic Article EphA2 mutation in lung squamous cell carcinoma promotes increased cell survival, cell invasion, focal adhesions, and mammalian target of rapamycin activation.
Academic Article Gefitinib response of erlotinib-refractory lung cancer involving meninges--role of EGFR mutation.
Academic Article Functional analysis of c-Met/hepatocyte growth factor pathway in malignant pleural mesothelioma.
Academic Article PAX6 is expressed in pancreatic cancer and actively participates in cancer progression through activation of the MET tyrosine kinase receptor gene.
Academic Article The role of chemokine receptor CXCR4 in lung cancer.
Academic Article Fyn: a novel molecular target in cancer.
Academic Article CBL is frequently altered in lung cancers: its relationship to mutations in MET and EGFR tyrosine kinases.
Academic Article c-Met overexpression is a prognostic factor in ovarian cancer and an effective target for inhibition of peritoneal dissemination and invasion.
Academic Article Rapid and dramatic radiographic and clinical response to an ALK inhibitor (crizotinib, PF02341066) in an ALK translocation-positive patient with non-small cell lung cancer.
Academic Article The novel role of the mu opioid receptor in lung cancer progression: a laboratory investigation.
Academic Article Chemotherapy and high dose radiotherapy followed by resection for locally advanced nonsmall cell lung cancers.
Academic Article Lysophosphatidic acid modulates c-Met redistribution and hepatocyte growth factor/c-Met signaling in human bronchial epithelial cells through PKC delta and E-cadherin.
Academic Article Preclinical studies of the proteasome inhibitor bortezomib in malignant pleural mesothelioma.
Academic Article Fyn is downstream of the HGF/MET signaling axis and affects cellular shape and tropism in PC3 cells.
Academic Article Downstream signalling and specific inhibition of c-MET/HGF pathway in small cell lung cancer: implications for tumour invasion.
Academic Article Proteomic characterization of non-small cell lung cancer in a comprehensive translational thoracic oncology database.
Academic Article Pathologic response rates following definitive dose image-guided chemoradiotherapy and resection for locally advanced non-small cell lung cancer.
Academic Article Non-receptor tyrosine kinase inhibitors in lung cancer.
Academic Article Takotsubo cardiomyopathy in a patient with squamous cell esophageal carcinoma.
Academic Article Inhibition of mitochondrial fission prevents cell cycle progression in lung cancer.
Academic Article Effect of a c-Met-specific, ATP-competitive small-molecule inhibitor SU11274 on human ovarian carcinoma cell growth, motility, and invasion.
Academic Article Randomized phase II Study of carboplatin and etoposide with or without the bcl-2 antisense oligonucleotide oblimersen for extensive-stage small-cell lung cancer: CALGB 30103.
Academic Article Autotaxin induces lung epithelial cell migration through lysoPLD activity-dependent and -independent pathways.
Academic Article Characterization of NOL7 gene point mutations, promoter methylation, and protein expression in cervical cancer.
Academic Article A novel classification of lung cancer into molecular subtypes.
Academic Article Prognostic value of metabolic tumor burden on 18F-FDG PET in nonsurgical patients with non-small cell lung cancer.
Academic Article Overexpression of the µ-opioid receptor in human non-small cell lung cancer promotes Akt and mTOR activation, tumor growth, and metastasis.
Academic Article Differential expression of RON in small and non-small cell lung cancers.
Academic Article Mind-mapping for lung cancer: towards a personalized therapeutics approach.
Academic Article PAX3 and SOX10 activate MET receptor expression in melanoma.
Academic Article The effects of monensin on membrane lipids of cultured human skin fibroblasts.
Academic Article Molecular cloning of human paxillin, a focal adhesion protein phosphorylated by P210BCR/ABL.
Academic Article Melanoma proteoglycan modifies gene expression to stimulate tumor cell motility, growth, and epithelial-to-mesenchymal transition.
Academic Article MET, HGF, EGFR, and PXN gene copy number in lung cancer using DNA extracts from FFPE archival samples and prognostic significance.
Academic Article Multicenter phase II trial of Motexafin gadolinium and pemetrexed for second-line treatment in patients with non-small cell lung cancer.
Academic Article MET and phosphorylated MET as potential biomarkers in lung cancer.
Academic Article Anaplastic lymphoma kinase inhibition in non-small-cell lung cancer.
Academic Article CD14(+)S100A9(+) myeloid-derived suppressor cells portend decreased survival in patients with advanced lung cancer.
Academic Article Factor independence of human myeloid leukemia cell lines is associated with increased phosphorylation of the proto-oncogene Raf-1.
Academic Article Functional EGFR germline polymorphisms may confer risk for EGFR somatic mutations in non-small cell lung cancer, with a predominant effect on exon 19 microdeletions.
Academic Article Phase 2 trial of Linifanib (ABT-869) in patients with advanced non-small cell lung cancer.
Academic Article Diffuse alveolar damage after a single dose of topotecan in a patient with pulmonary fibrosis and small cell lung cancer.
Academic Article Inhibition of MET receptor tyrosine kinase and its ligand hepatocyte growth factor.
Academic Article Targeted and cytotoxic therapy in coordinated sequence (TACTICS): erlotinib, bevacizumab, and standard chemotherapy for non-small-cell lung cancer, a phase II trial.
Academic Article Hypofractionated image-guided radiation therapy for patients with limited volume metastatic non-small cell lung cancer.
Academic Article Changes in Tc-99m radionuclide bone scan images and peripheralization of marrow hematopoietic activity associated with the administration of granulocyte colony stimulating factor as an adjunct to dose-intensified chemotherapy for breast cancer. A case report.
Academic Article Sphingosine kinase 1 is required for mesothelioma cell proliferation: role of histone acetylation.
Academic Article c-Met is a potentially new therapeutic target for treatment of human melanoma.
Academic Article CRKL links p210BCR/ABL with paxillin in chronic myelogenous leukemia cells.
Academic Article Shc phosphorylation in myeloid cells is regulated by granulocyte macrophage colony-stimulating factor, interleukin-3, and steel factor and is constitutively increased by p210BCR/ABL.
Academic Article The thrombopoietin receptor c-MPL activates JAK2 and TYK2 tyrosine kinases.
Academic Article Altered membrane fluidity in rat hepatocytes during endotoxic shock.
Academic Article Paxillin is a target for somatic mutations in lung cancer: implications for cell growth and invasion.
Academic Article MET molecular mechanisms and therapies in lung cancer.
Academic Article Novel oncogenic mutations of CBL in human acute myeloid leukemia that activate growth and survival pathways depend on increased metabolism.
Academic Article NADPH oxidases regulate cell growth and migration in myeloid cells transformed by oncogenic tyrosine kinases.
Academic Article Personalized treatment of lung cancer.
Academic Article An E3 ubiquitin ligase: c-Cbl: a new therapeutic target of lung cancer.
Academic Article Novel functional germline variants in the VEGF receptor 2 gene and their effect on gene expression and microvessel density in lung cancer.
Academic Article Prognostic significance of angiogenesis and angiogenic growth factors in nonsmall cell lung cancer.
Academic Article Effect of crizotinib on overall survival in patients with advanced non-small-cell lung cancer harbouring ALK gene rearrangement: a retrospective analysis.
Academic Article Phase II study of the multitargeted tyrosine kinase inhibitor XL647 in patients with non-small-cell lung cancer.
Academic Article Activity and safety of crizotinib in patients with ALK-positive non-small-cell lung cancer: updated results from a phase 1 study.
Academic Article Targeting ALK: a promising strategy for the treatment of non-small cell lung cancer, non-Hodgkin's lymphoma, and neuroblastoma.
Academic Article Differential signaling after beta1 integrin ligation is mediated through binding of CRKL to p120(CBL) and p110(HEF1).
Academic Article Role of the adapter protein CRKL in signal transduction of normal hematopoietic and BCR/ABL-transformed cells.
Academic Article Involvement of the adapter protein CRKL in integrin-mediated adhesion.
Academic Article Inhibition of epidermal growth factor receptor signaling in malignant pleural mesothelioma.
Academic Article Detection and analysis of lung cancer cells from body fluids using a rare event imaging system.
Academic Article Molecular and cellular biology of small cell lung cancer.
Academic Article Unusual problems in breast cancer and a rare lung cancer case. Case 4. Primary lymphoepithelioma-like carcinoma of the lung.
Academic Article A novel small molecule met inhibitor induces apoptosis in cells transformed by the oncogenic TPR-MET tyrosine kinase.
Academic Article Mechanisms of metastasis as related to receptor tyrosine kinases in small-cell lung cancer.
Academic Article Haptoglobin alpha-subunit and hepatocyte growth factor can potentially serve as serum tumor biomarkers in small cell lung cancer.
Academic Article A phase I study of pemetrexed, carboplatin, and concurrent radiotherapy in patients with locally advanced or metastatic non-small cell lung or esophageal cancer.
Academic Article CD44 regulates hepatocyte growth factor-mediated vascular integrity. Role of c-Met, Tiam1/Rac1, dynamin 2, and cortactin.
Academic Article Disruption of the EGFR E884-R958 ion pair conserved in the human kinome differentially alters signaling and inhibitor sensitivity.
Academic Article Novel targets for therapeutic agents in small cell lung cancer.
Academic Article The role of EGFR inhibition in the treatment of non-small cell lung cancer.
Academic Article Phase II study of amrubicin as second-line therapy in patients with platinum-refractory small-cell lung cancer.
Academic Article RON (MST1R) is a novel prognostic marker and therapeutic target for gastroesophageal adenocarcinoma.
Academic Article Activity of crizotinib (PF02341066), a dual mesenchymal-epithelial transition (MET) and anaplastic lymphoma kinase (ALK) inhibitor, in a non-small cell lung cancer patient with de novo MET amplification.
Academic Article Role of MetMAb (OA-5D5) in c-MET active lung malignancies.
Academic Article A phase I trial of pan-Bcl-2 antagonist obatoclax administered as a 3-h or a 24-h infusion in combination with carboplatin and etoposide in patients with extensive-stage small cell lung cancer.
Academic Article Degradation and regurgitation of extracellular proteins by cultured mouse peritoneal macrophages and baby hamster kidney fibroblasts. Kinetic evidence that the transfer of proteins to lysosomes is not irreversible.
Academic Article Increased tyrosine phosphorylation of focal adhesion proteins in myeloid cell lines expressing p210BCR/ABL.
Academic Article Critical role for the receptor tyrosine kinase EPHB4 in esophageal cancers.
Academic Article Lack of association of C-Met-N375S sequence variant with lung cancer susceptibility and prognosis.
Academic Article The EphB4 receptor tyrosine kinase promotes lung cancer growth: a potential novel therapeutic target.
Academic Article Evidence-based role of bevacizumab in non-small cell lung cancer.
Academic Article A multicenter phase II study of ganetespib monotherapy in patients with genotypically defined advanced non-small cell lung cancer.
Academic Article MET as a possible target for non-small-cell lung cancer.
Academic Article Nuclear EGFR protein expression predicts poor survival in early stage non-small cell lung cancer.
Academic Article Etoposide and temozolomide in combination for the treatment of progressive small-cell lung cancer central nervous system metastases: two cases.
Academic Article Critical role of S1PR1 and integrin ß4 in HGF/c-Met-mediated increases in vascular integrity.
Academic Article EphB4 as a therapeutic target in mesothelioma.
Academic Article Initial clinical sensitivity and acquired resistance to MET inhibition in MET-mutated papillary renal cell carcinoma.
Academic Article Lipopolysaccharide-induced phosphorylation of c-Met tyrosine residue 1003 regulates c-Met intracellular trafficking and lung epithelial barrier function.
Academic Article Paxillin mutations affect focal adhesions and lead to altered mitochondrial dynamics: relevance to lung cancer.
Academic Article Targeted agents in non-small cell lung cancer therapy: What is there on the horizon?
Academic Article Transactivation of the receptor-tyrosine kinase ephrin receptor A2 is required for the low molecular weight hyaluronan-mediated angiogenesis that is implicated in tumor progression.
Academic Article Increased µ-opioid receptor expression in metastatic lung cancer.
Academic Article The Mu opioid receptor promotes opioid and growth factor-induced proliferation, migration and Epithelial Mesenchymal Transition (EMT) in human lung cancer.
Academic Article Role of c-Met/phosphatidylinositol 3-kinase (PI3k)/Akt signaling in hepatocyte growth factor (HGF)-mediated lamellipodia formation, reactive oxygen species (ROS) generation, and motility of lung endothelial cells.
Academic Article Activating the expression of human K-rasG12D stimulates oncogenic transformation in transgenic goat fetal fibroblast cells.
Academic Article Expression of the EPHB4 receptor tyrosine kinase in head and neck and renal malignancies--implications for solid tumors and potential for therapeutic inhibition.
Academic Article MET and PI3K/mTOR as a potential combinatorial therapeutic target in malignant pleural mesothelioma.
Academic Article Role of PAX8 in the regulation of MET and RON receptor tyrosine kinases in non-small cell lung cancer.
Academic Article Integrative analysis of head and neck cancer identifies two biologically distinct HPV and three non-HPV subtypes.
Academic Article Crizotinib in ROS1-rearranged non-small-cell lung cancer.
Academic Article Brain metastases in non-small-cell lung cancer: better outcomes through current therapies and utilization of molecularly targeted approaches.
Academic Article Non-small cell lung cancer is susceptible to induction of DNA damage responses and inhibition of angiogenesis by telomere overhang oligonucleotides.
Academic Article Multiple Endocrine Disruption by the MET/ALK Inhibitor Crizotinib in Patients With Non-small Cell Lung Cancer.
Academic Article Combined MET inhibition and topoisomerase I inhibition block cell growth of small cell lung cancer.
Academic Article Dramatic antitumor effects of the dual MET/RON small-molecule inhibitor LY2801653 in non-small cell lung cancer.
Academic Article Targeting myeloid-derived suppressor cells augments antitumor activity against lung cancer.
Academic Article Evaluation of a novel rash scale and a serum proteomic predictor in a randomized phase II trial of sequential or concurrent cetuximab and pemetrexed in previously treated non-small cell lung cancer.
Academic Article Fibroblast growth factor signaling and inhibition in non-small cell lung cancer and their role in squamous cell tumors.
Academic Article A personalized treatment for lung cancer: molecular pathways, targeted therapies, and genomic characterization.
Academic Article AXL mediates resistance to cetuximab therapy.
Academic Article Overcoming acquired resistance to cetuximab by dual targeting HER family receptors with antibody-based therapy.
Academic Article A safety assessment of crizotinib in the treatment of ALK-positive NSCLC patients.
Academic Article Molecularly targeted therapies in non-small-cell lung cancer annual update 2014.
Academic Article Diagnostic challenges in non-small-cell lung cancer: an integrated medicine approach.
Academic Article Nuclear epidermal growth factor receptor is a functional molecular target in triple-negative breast cancer.
Academic Article c-Abl mediated tyrosine phosphorylation of paxillin regulates LPS-induced endothelial dysfunction and lung injury.
Academic Article AXL Is a Logical Molecular Target in Head and Neck Squamous Cell Carcinoma.
Academic Article A new PET/CT volumetric prognostic index for non-small cell lung cancer.
Academic Article Novel EPHB4 Receptor Tyrosine Kinase Mutations and Kinomic Pathway Analysis in Lung Cancer.
Academic Article A randomized phase II study of ganetespib, a heat shock protein 90 inhibitor, in combination with docetaxel in second-line therapy of advanced non-small cell lung cancer (GALAXY-1).
Academic Article Engineering Synthetic Antibody Inhibitors Specific for LD2 or LD4 Motifs of Paxillin.
Academic Article PAX3 and FOXD3 Promote CXCR4 Expression in Melanoma.
Academic Article Phase II Study of the AKT Inhibitor MK-2206 plus Erlotinib in Patients with Advanced Non-Small Cell Lung Cancer Who Previously Progressed on Erlotinib.
Academic Article ROS1 rearranged non-small cell lung cancer brain metastases respond to low dose radiotherapy.
Academic Article C. elegans and mutants with chronic nicotine exposure as a novel model of cancer phenotype.
Academic Article Selumetinib with and without erlotinib in KRAS mutant and KRAS wild-type advanced nonsmall-cell lung cancer.
Academic Article Systemic therapies in the treatment of non-small-cell lung cancer brain metastases.
Academic Article Small Cell Lung Cancer: Can Recent Advances in Biology and Molecular Biology Be Translated into Improved Outcomes?
Academic Article Concurrent EGFR Mutation and ALK Translocation in Non-Small Cell Lung Cancer.
Academic Article Unique fractal evaluation and therapeutic implications of mitochondrial morphology in malignant mesothelioma.
Academic Article Oncoprotein ZNF322A transcriptionally deregulates alpha-adducin, cyclin D1 and p53 to promote tumor growth and metastasis in lung cancer.
Academic Article 1330: Brigatinib efficacy and safety in patients (Pts) with anaplastic lymphoma kinase (ALK)-positive (ALK+) non-small cell lung cancer (NSCLC) in a phase 1/2 trial.
Academic Article Effective growth-suppressive activity of maternal embryonic leucine-zipper kinase (MELK) inhibitor against small cell lung cancer.
Academic Article Prognostic and Predictive Value in KRAS in Non-Small-Cell Lung Cancer: A Review.
Academic Article Mutation testing for directing upfront targeted therapy and post-progression combination therapy strategies in lung adenocarcinoma.
Academic Article Comprehensive Genomic Profiling Identifies a Subset of Crizotinib-Responsive ALK-Rearranged Non-Small Cell Lung Cancer Not Detected by Fluorescence In Situ Hybridization.
Academic Article Comprehensive genetic testing identifies targetable genomic alterations in most patients with non-small cell lung cancer, specifically adenocarcinoma, single institute investigation.
Academic Article Post-crizotinib management of effective ceritinib therapy in a patient with ALK-positive non-small cell lung cancer.
Academic Article Met gene amplification and protein hyperactivation is a mechanism of resistance to both first and third generation EGFR inhibitors in lung cancer treatment.
Academic Article Targeting the HER Family with Pan-HER Effectively Overcomes Resistance to Cetuximab.
Academic Article PI3 Kinase Pathway and MET Inhibition is Efficacious in Malignant Pleural Mesothelioma.
Academic Article DIFFERENTIAL SERUM LEVEL OF SPECIFIC HAPTOGLOBIN ISOFORMS IN SMALL CELL LUNG CANCER.
Academic Article KRAS in Non-Small-Cell Lung Cancer-Reply.
Academic Article Activity and safety of brigatinib in ALK-rearranged non-small-cell lung cancer and other malignancies: a single-arm, open-label, phase 1/2 trial.
Academic Article RETRACTED: The receptor tyrosine kinase AXL mediates nuclear translocation of the epidermal growth factor receptor.
Academic Article Biopsy-free circulating tumor DNA assay identifies actionable mutations in lung cancer.
Academic Article TOPK (T-LAK cell-originated protein kinase) inhibitor exhibits growth suppressive effect on small cell lung cancer.
Academic Article A phase I dose-escalating study of combination pemetrexed-based chemotherapy and concomitant radiotherapy for locally advanced or metastatic non-small cell lung or esophageal cancer.
Academic Article Expression and mutational analysis of c-CBL and its relationship to the MET receptor in head and neck squamous cell carcinoma.
Academic Article CALGB 30103: A randomized phase II study of carboplatin and etoposide (CE) with or without G3139 in patients with extensive stage small cell lung cancer (ES-SCLC).
Academic Article Refining epidermal growth factor receptor (EGFR) -inhibition-related rash (EIRR) phenotypes with a cetuximab (C) monotherapy stage of a phase II trial for non-small cell lung cancer (NSCLC).
Academic Article A phase 1/2 study of STA-4783 in combination with paclitaxel and carboplatin in chemo-naïve advanced non-small cell lung cancer (NSCLC).
Academic Article Phase II trial of sequential bevacizumab (B), erlotinib (E) and chemotherapy for first line treatment of clinical stage IIIB or IV non-small cell lung cancer (NSCLC).
Academic Article A randomized phase II study of LY2510924 and carboplatin/etoposide versus carboplatin/etoposide in extensive-disease small cell lung cancer.
Academic Article Prognostic and predictive value of circulating tumor cells and CXCR4 expression as biomarkers for a CXCR4 peptide antagonist in combination with carboplatin-etoposide in small cell lung cancer: exploratory analysis of a phase II study.
Academic Article MET in Lung Cancer: Biomarker Selection Based on Scientific Rationale.
Academic Article The accelerated path of ceritinib: Translating pre-clinical development into clinical efficacy.
Academic Article Camptothecin resistance is determined by the regulation of topoisomerase I degradation mediated by ubiquitin proteasome pathway.
Academic Article Loss of H2B monoubiquitination is associated with poor-differentiation and enhanced malignancy of lung adenocarcinoma.
Academic Article Complete Pathologic Response When Adding Pembrolizumab to Neoadjuvant Chemotherapy in Stage IIIA Non-Small-Cell Lung Cancer.
Academic Article Effective osimertinib treatment in a patient with discordant T790 M mutation detection between liquid biopsy and tissue biopsy.
Academic Article Differential responsiveness of MET inhibition in non-small-cell lung cancer with altered CBL.
Academic Article Correction: AXL Is a Logical Molecular Target in Head and Neck Squamous Cell Carcinoma.
Academic Article Phase 1 Study of Accelerated Hypofractionated Radiation Therapy With Concurrent Chemotherapy for Stage III Non-Small Cell Lung Cancer: CALGB 31102 (Alliance).
Academic Article Acute myeloid leukemia cells require 6-phosphogluconate dehydrogenase for cell growth and NADPH-dependent metabolic reprogramming.
Academic Article 2'-Hydroxyflavanone induced changes in the proteomic profile of breast cancer cells.
Academic Article Development of PD-1 and PD-L1 inhibitors as a form of cancer immunotherapy: a comprehensive review of registration trials and future considerations.
Academic Article EphB4: A promising target for upper aerodigestive malignancies.
Academic Article Stereotactic body radiation therapy (SBRT) for early-stage lung cancer in the elderly.
Academic Article Modeling small cell lung cancer (SCLC) biology through deterministic and stochastic mathematical models.
Academic Article 2'-Hydroxyflavanone inhibits in vitro and in vivo growth of breast cancer cells by targeting RLIP76.
Academic Article Metastasis of breast tumor cells to brain is suppressed by targeting RLIP alone and in combination with 2'-Hydroxyflavanone.
Academic Article Managing Patients With Relapsed Small-Cell Lung Cancer.
Academic Article The brigatinib experience: a new generation of therapy for ALK-positive non-small-cell lung cancer.
Academic Article Exosomal miRNAs species in the blood of small cell and non-small cell lung cancer patients.
Academic Article Focal adhesion kinase a potential therapeutic target for pancreatic cancer and malignant pleural mesothelioma.
Academic Article B-Cell-Specific Diversion of Glucose Carbon Utilization Reveals a Unique Vulnerability in B Cell Malignancies.
Academic Article State-of-the-art considerations in small cell lung cancer brain metastases.
Academic Article Responses to Alectinib in ALK-rearranged Papillary Renal Cell Carcinoma.
Academic Article A phase I open-label dose-escalation study of the anti-HER3 monoclonal antibody LJM716 in patients with advanced squamous cell carcinoma of the esophagus or head and neck and HER2-overexpressing breast or gastric cancer.
Academic Article The DNA walk and its demonstration of deterministic chaos-relevance to genomic alterations in lung cancer.
Academic Article RLIP inhibition suppresses breast-to-lung metastasis.
Academic Article Anaplastic Lymphoma Kinase (ALK)-positive Tumors: Clinical, Radiographic and Molecular Profiles, and Uncommon Sites of Metastases in Patients With Lung Adenocarcinoma.
Academic Article RLIP: An existential requirement for breast carcinogenesis.
Academic Article Combined Checkpoint Inhibition and Chemotherapy: New Era of 1st-Line Treatment for Non-Small-Cell Lung Cancer.
Academic Article Early mortality of stage IV non-small cell lung cancer in the United States.
Academic Article Synergistic efficacy of RLIP inhibition and 2'-hydroxyflavanone against DMBA-induced mammary carcinogenesis in SENCAR mice.
Academic Article Optimal adjuvant therapy in clinically N2 non-small cell lung cancer patients undergoing neoadjuvant chemotherapy and surgery: The importance of pathological response and lymph node ratio.
Academic Article Targeted Therapies in Non-small-Cell Lung Cancer.
Academic Article Small Cell Lung Cancer Therapeutic Responses Through Fractal Measurements: From Radiology to Mitochondrial Biology.
Academic Article Patterns of Biomarker Testing Rates and Appropriate Use of Targeted Therapy in the First-Line, Metastatic Non-Small Cell Lung Cancer Treatment Setting.
Academic Article EPHA2 mutations with oncogenic characteristics in squamous cell lung cancer and malignant pleural mesothelioma.
Academic Article Monitoring and Determining Mitochondrial Network Parameters in Live Lung Cancer Cells.
Academic Article Phenotypic Switching of Naïve T Cells to Immune-Suppressive Treg-Like Cells by Mutant KRAS.
Academic Article Ubiquitin-specific protease 22 is critical to in vivo angiogenesis, growth and metastasis of non-small cell lung cancer.
Academic Article RLIP controls receptor-ligand signaling by regulating clathrin-dependent endocytosis.
Academic Article SOX9: The master regulator of cell fate in breast cancer.
Academic Article Effects of selected deubiquitinating enzyme inhibitors on the proliferation and motility of lung cancer and mesothelioma cell lines.
Academic Article The promise of selective MET inhibitors in non-small cell lung cancer with MET exon 14 skipping.
Academic Article Therapeutic targeting of miRNA-216b in cancer.
Academic Article Differentiating Peripherally-Located Small Cell Lung Cancer From Non-small Cell Lung Cancer Using a CT Radiomic Approach.
Academic Article Targeting RLIP with CRISPR/Cas9 controls tumor growth.
Academic Article AXL Mediates Cetuximab and Radiation Resistance Through Tyrosine 821 and the c-ABL Kinase Pathway in Head and Neck Cancer.
Academic Article Targeting FTO Suppresses Cancer Stem Cell Maintenance and Immune Evasion.
Academic Article Association of molecular characteristics with survival in advanced non-small cell lung cancer patients treated with checkpoint inhibitors.
Academic Article Non-Small Cell Lung Cancer from Genomics to Therapeutics: A Framework for Community Practice Integration to Arrive at Personalized Therapy Strategies.
Academic Article Evaluation of Omics-Based Strategies for the Management of Advanced Lung Cancer.
Academic Article Progressive Neurologic Changes in a Patient With Metastatic Non-Small-Cell Lung Cancer: Cancer Effects or a Secondary Diagnosis?
Academic Article Lysocardiolipin acyltransferase regulates NSCLC cell proliferation and migration by modulating mitochondrial dynamics.
Academic Article Small Cell Lung Cancer from Traditional to Innovative Therapeutics: Building a Comprehensive Network to Optimize Clinical and Translational Research.
Academic Article The Effects of Time to Treatment Initiation for Patients With Non-small-cell Lung Cancer in the United States.
Academic Article Activation of EPHA2-ROBO1 Heterodimer by SLIT2 Attenuates Non-canonical Signaling and Proliferation in Squamous Cell Carcinomas.
Academic Article Epigenetic landscape of small cell lung cancer: small image of a giant recalcitrant disease.
Academic Article Hyperprogression on immunotherapy with complete response to chemotherapy in a NSCLC patient with high PD-L1 and STK11: A case report.
Academic Article Role of immunotherapy and co-mutations on KRAS-mutant non-small cell lung cancer survival.
Academic Article Prolonged survival and response to tepotinib in a non-small-cell lung cancer patient with brain metastases harboring MET exon 14 mutation: a research report.
Academic Article Prevention of mammary carcinogenesis in MMTV-neu mice by targeting RLIP.
Academic Article The improbable targeted therapy: KRAS as an emerging target in non-small cell lung cancer (NSCLC).
Academic Article RLIP depletion induces apoptosis associated with inhibition of JAK2/STAT3 signaling in melanoma cells.
Academic Article Therapeutic Potential of Olaparib in Combination With Pembrolizumab in a Young Patient With a Maternally Inherited BRCA2 Germline Variant: A Research Report.
Academic Article Quantifying Cancer: More Than Just a Numbers Game.
Academic Article Improving Care for Patients With Stage III or IV NSCLC: Learnings for Multidisciplinary Teams From the ACCC National Quality Survey.
Academic Article Improved Survival Outcomes in Medically Fit Patients With Early-Stage Non-Small-Cell Lung Cancer Undergoing Stereotactic Body Radiotherapy.
Academic Article Disparate outcomes in nonsmall cell lung cancer by immigration status.
Academic Article Predicting Survival Duration With MRI Radiomics of Brain Metastases From Non-small Cell Lung Cancer.
Academic Article Usefulness of Circulating Tumor DNA in Identifying Somatic Mutations and Tracking Tumor Evolution in Patients With Non-small Cell Lung Cancer.
Academic Article The Small Molecule BC-2059 Inhibits Wingless/Integrated (Wnt)-Dependent Gene Transcription in Cancer through Disruption of the Transducin ß-Like 1-ß-Catenin Protein Complex.
Academic Article Evolution of core archetypal phenotypes in progressive high grade serous ovarian cancer.
Academic Article MicroRNA-1: Diverse role of a small player in multiple cancers.
Academic Article The Association between Polluted Neighborhoods and TP53-Mutated Non-Small Cell Lung Cancer.
Academic Article Essential role of the histone lysine demethylase KDM4A in the biology of malignant pleural mesothelioma (MPM).
Academic Article Protein Phosphatase 2A as a Therapeutic Target in Small Cell Lung Cancer.
Academic Article Immunotherapy in Non-Small Cell Lung Cancer Patients with Brain Metastases: Clinical Challenges and Future Directions.
Academic Article Elevated Eosinophil Count Following Pembrolizumab Treatment for Non-Small Cell Lung Cancer.
Academic Article Biologically Active Volume of Disease (BaVD) Predicts for Survival in Metastatic Non-Small Cell Lung Cancer.
Academic Article Infectious complications of immune checkpoint inhibitors in solid organ malignancies.
Academic Article Patterns of Care in Maintenance Therapy in US Patients Undergoing Definitive Chemoradiation for Stage 3 Non-Small Cell Lung Cancer (NSCLC).
Academic Article ALK-Directed Therapy in Non-NSCLC Malignancies: Are We Ready?
Academic Article The next targets for small cell lung cancer.
Academic Article Dynamic Phenotypic Switching and Group Behavior Help Non-Small Cell Lung Cancer Cells Evade Chemotherapy.
Academic Article Postoperative Radiation Therapy Should Be Used for Completely Resected Stage III-N2 NSCLC in Select Patients.
Academic Article Small Cell Lung Cancer Transformation following Treatment in EGFR-Mutated Non-Small Cell Lung Cancer.
Academic Article AXL regulates neuregulin1 expression leading to cetuximab resistance in head and neck cancer.
Academic Article Correction: Protein Phosphatase 2A as a Therapeutic Target in Small Cell Lung Cancer.
Academic Article Report of the First International Symposium on NUT Carcinoma.
Academic Article Machine learning to refine prognostic and predictive nodal burden thresholds for post-operative radiotherapy in completely resected stage III-N2 non-small cell lung cancer.
Academic Article Chemokines and NSCLC: Emerging role in prognosis, heterogeneity, and therapeutics.
Academic Article Exploring the Next Frontier in Non-Small-Cell Lung Cancer With High MET and Mutated Epidermal Growth Factor Receptor.
Academic Article MicroRNA-1 attenuates the growth and metastasis of small cell lung cancer through CXCR4/FOXM1/RRM2 axis.
Academic Article Neighborhood disadvantage is associated with KRAS-mutated non-small cell lung cancer risk.
Academic Article A Systems Biology Approach for Addressing Cisplatin Resistance in Non-Small Cell Lung Cancer.
Academic Article Integration of artificial intelligence in lung cancer: Rise of the machine.
Academic Article Prognostic Role of Biologically Active Volume of Disease in Patients With Metastatic Lung Adenocarcinoma.
Academic Article Management of infusion-related reactions (IRRs) in patients receiving amivantamab in the CHRYSALIS study.
Academic Article A Closer Look at EGFR Inhibitor Resistance in Non-Small Cell Lung Cancer through the Lens of Precision Medicine.
Concept Cell Self Renewal
Concept A549 Cells
Concept Cell Surface Display Techniques
Concept MCF-7 Cells
Grant ABNORMALITIES OF MOTILITY OF CML CELLS
Grant Role of Paxillin in Lung Cancer
Grant MINIMAL RESIDUAL TUMOR IN SMALL CELL LUNG CANCER
Grant Role of c-Met in SCLC and Potential for Novel Therapy
Grant Novel Targeted Therapy in Pancreatic Cancer
Grant Studies of a Novel Therapeutic Target in Non-Small Cell Lung Cancer (NSCLC)
Grant PAXILLIN--AN ONCOGENE ACTIVATED PROTEIN
Academic Article Twelve-Month Follow-up of the Immune Response After COVID-19 Vaccination in Patients with Genitourinary Cancers: A Prospective Cohort Analysis.
Academic Article Complete response to chemoimmunotherapy with bevacizumab in synchronous multiple primary cancers: pulmonary adenocarcinoma and sarcomatoid carcinoma.
Academic Article Dual Axl/MerTK inhibitor INCB081776 creates a proinflammatory tumor immune microenvironment and enhances anti-PDL1 efficacy in head and neck cancer.
Academic Article LSD1-targeted therapy-a multi-purpose key to unlock immunotherapy in small cell lung cancer.
Academic Article Differential Distribution of Brain Metastases from Non-Small Cell Lung Cancer Based on Mutation Status.
Academic Article Stereotactic Body Radiation Therapy for Oligoprogressive and Oligorecurrent Non-Small-Cell Lung Cancer.
Academic Article Targeting ITGB4/SOX2-driven lung cancer stem cells using proteasome inhibitors.
Academic Article Targeted Therapies in Early-Stage Resectable Non-Small-Cell Lung Cancer: New Kids on the Block.
Academic Article Acquired resistance to KRAS G12C small-molecule inhibitors via genetic/nongenetic mechanisms in lung cancer.
Academic Article Regression of ovarian cancer xenografts by depleting or inhibiting RLIP.
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