| Item Type | Name |
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Concept
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Insulin-Like Growth Factor I
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Concept
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Hepatocyte Growth Factor
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Concept
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Transforming Growth Factor beta
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Concept
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Receptors, Fibroblast Growth Factor
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Concept
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Receptors, Growth Factor
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Concept
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Vascular Endothelial Growth Factor Receptor-2
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Concept
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Transcription Factor AP-1
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Concept
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Stem Cell Factor
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Concept
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STAT3 Transcription Factor
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Concept
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Microphthalmia-Associated Transcription Factor
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Concept
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Receptors, Vascular Endothelial Growth Factor
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Concept
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SOX9 Transcription Factor
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Concept
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PAX5 Transcription Factor
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Concept
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Transcription Factor RelA
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Concept
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Granulocyte Colony-Stimulating Factor
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Concept
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STAT1 Transcription Factor
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Concept
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STAT5 Transcription Factor
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Concept
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Vascular Endothelial Growth Factor A
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Concept
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Ikaros Transcription Factor
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Concept
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Epidermal Growth Factor
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Concept
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Granulocyte-Macrophage Colony-Stimulating Factor
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Concept
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Vascular Endothelial Growth Factor Receptor-1
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Academic Article
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Interleukin-3 and p210 BCR/ABL activate both unique and overlapping pathways of signal transduction in a factor-dependent myeloid cell line.
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Academic Article
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Steel factor induces tyrosine phosphorylation of CRKL and binding of CRKL to a complex containing c-kit, phosphatidylinositol 3-kinase, and p120(CBL).
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Academic Article
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Activation of hematopoietic growth factor signal transduction pathways by the human oncogene BCR/ABL.
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Academic Article
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Hematopoietic growth factors signal through the formation of reactive oxygen species.
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Academic Article
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The BCR/ABL oncogene alters the chemotactic response to stromal-derived factor-1alpha.
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Academic Article
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Chemokine receptors CXCR-1/2 activate mitogen-activated protein kinase via the epidermal growth factor receptor in ovarian cancer cells.
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Academic Article
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Vascular endothelial growth factor-induced migration of multiple myeloma cells is associated with beta 1 integrin- and phosphatidylinositol 3-kinase-dependent PKC alpha activation.
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Academic Article
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ATP6S1 elicits potent humoral responses associated with immune-mediated tumor destruction.
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Academic Article
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Role of the cytoskeletal protein paxillin in oncogenesis.
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Academic Article
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Role of the hepatocyte growth factor receptor, c-Met, in oncogenesis and potential for therapeutic inhibition.
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Academic Article
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Vaccination with irradiated autologous tumor cells engineered to secrete granulocyte-macrophage colony-stimulating factor augments antitumor immunity in some patients with metastatic non-small-cell lung carcinoma.
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Academic Article
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Modulation of the c-Met/hepatocyte growth factor pathway in small cell lung cancer.
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Academic Article
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c-Met as a target for human cancer and characterization of inhibitors for therapeutic intervention.
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Academic Article
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Activation of HGF/c-Met pathway contributes to the reactive oxygen species generation and motility of small cell lung cancer cells.
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Academic Article
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A selective small molecule inhibitor of c-Met, PHA665752, inhibits tumorigenicity and angiogenesis in mouse lung cancer xenografts.
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Academic Article
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Epidermal growth factor receptor mutations and susceptibility to targeted therapy in lung cancer.
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Academic Article
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Epidermal growth factor receptor - mediated signal transduction in the development and therapy of gliomas.
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Academic Article
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c-Met: structure, functions and potential for therapeutic inhibition.
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Academic Article
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c-Met and hepatocyte growth factor: potential as novel targets in cancer therapy.
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Academic Article
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Efficacy and safety of bevacizumab plus erlotinib for patients with recurrent ovarian, primary peritoneal, and fallopian tube cancer: a trial of the Chicago, PMH, and California Phase II Consortia.
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Academic Article
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PAX5 is expressed in small-cell lung cancer and positively regulates c-Met transcription.
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Academic Article
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The MET receptor tyrosine kinase is a potential novel therapeutic target for head and neck squamous cell carcinoma.
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Academic Article
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Lymphatic vessel density is not associated with lymph node metastasis in non-small cell lung carcinoma.
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Academic Article
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The role of ephrins and Eph receptors in cancer.
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Academic Article
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Expression and mutational analysis of MET in human solid cancers.
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Academic Article
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MET pathway as a therapeutic target.
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Academic Article
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Functional analysis of c-Met/hepatocyte growth factor pathway in malignant pleural mesothelioma.
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Academic Article
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PAX6 is expressed in pancreatic cancer and actively participates in cancer progression through activation of the MET tyrosine kinase receptor gene.
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Academic Article
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CBL is frequently altered in lung cancers: its relationship to mutations in MET and EGFR tyrosine kinases.
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Academic Article
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c-Met overexpression is a prognostic factor in ovarian cancer and an effective target for inhibition of peritoneal dissemination and invasion.
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Academic Article
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Rapid and dramatic radiographic and clinical response to an ALK inhibitor (crizotinib, PF02341066) in an ALK translocation-positive patient with non-small cell lung cancer.
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Academic Article
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Lysophosphatidic acid modulates c-Met redistribution and hepatocyte growth factor/c-Met signaling in human bronchial epithelial cells through PKC delta and E-cadherin.
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Academic Article
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Fyn is downstream of the HGF/MET signaling axis and affects cellular shape and tropism in PC3 cells.
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Academic Article
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Downstream signalling and specific inhibition of c-MET/HGF pathway in small cell lung cancer: implications for tumour invasion.
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Academic Article
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Inhibition of MET receptor tyrosine kinase and its ligand hepatocyte growth factor.
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Academic Article
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PAX3 and SOX10 activate MET receptor expression in melanoma.
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Academic Article
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MET, HGF, EGFR, and PXN gene copy number in lung cancer using DNA extracts from FFPE archival samples and prognostic significance.
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Academic Article
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MET and phosphorylated MET as potential biomarkers in lung cancer.
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Academic Article
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Anaplastic lymphoma kinase inhibition in non-small-cell lung cancer.
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Academic Article
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Factor independence of human myeloid leukemia cell lines is associated with increased phosphorylation of the proto-oncogene Raf-1.
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Academic Article
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Role of protein kinase C ß and vascular endothelial growth factor receptor in malignant pleural mesothelioma: Therapeutic implications and the usefulness of Caenorhabditis elegans model organism.
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Academic Article
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Inhibition of MET receptor tyrosine kinase and its ligand hepatocyte growth factor.
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Academic Article
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Changes in Tc-99m radionuclide bone scan images and peripheralization of marrow hematopoietic activity associated with the administration of granulocyte colony stimulating factor as an adjunct to dose-intensified chemotherapy for breast cancer. A case report.
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Academic Article
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c-Met is a potentially new therapeutic target for treatment of human melanoma.
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Academic Article
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Shc phosphorylation in myeloid cells is regulated by granulocyte macrophage colony-stimulating factor, interleukin-3, and steel factor and is constitutively increased by p210BCR/ABL.
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Academic Article
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The thrombopoietin receptor c-MPL activates JAK2 and TYK2 tyrosine kinases.
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Academic Article
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Novel oncogenic mutations of CBL in human acute myeloid leukemia that activate growth and survival pathways depend on increased metabolism.
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Academic Article
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Personalized treatment of lung cancer.
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Academic Article
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Novel functional germline variants in the VEGF receptor 2 gene and their effect on gene expression and microvessel density in lung cancer.
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Academic Article
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Prognostic significance of angiogenesis and angiogenic growth factors in nonsmall cell lung cancer.
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Academic Article
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Inhibition of epidermal growth factor receptor signaling in malignant pleural mesothelioma.
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Academic Article
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Haptoglobin alpha-subunit and hepatocyte growth factor can potentially serve as serum tumor biomarkers in small cell lung cancer.
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Academic Article
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CD44 regulates hepatocyte growth factor-mediated vascular integrity. Role of c-Met, Tiam1/Rac1, dynamin 2, and cortactin.
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Academic Article
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Disruption of the EGFR E884-R958 ion pair conserved in the human kinome differentially alters signaling and inhibitor sensitivity.
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Academic Article
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Expression patterns of PAX5, c-Met, and paxillin in neuroendocrine tumors of the lung.
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Academic Article
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RON (MST1R) is a novel prognostic marker and therapeutic target for gastroesophageal adenocarcinoma.
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Academic Article
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Activity of crizotinib (PF02341066), a dual mesenchymal-epithelial transition (MET) and anaplastic lymphoma kinase (ALK) inhibitor, in a non-small cell lung cancer patient with de novo MET amplification.
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Academic Article
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Role of MetMAb (OA-5D5) in c-MET active lung malignancies.
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Academic Article
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Durable complete response of metastatic gastric cancer with anti-Met therapy followed by resistance at recurrence.
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Academic Article
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MET as a possible target for non-small-cell lung cancer.
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Academic Article
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Critical role of S1PR1 and integrin ß4 in HGF/c-Met-mediated increases in vascular integrity.
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Academic Article
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The Mu opioid receptor promotes opioid and growth factor-induced proliferation, migration and Epithelial Mesenchymal Transition (EMT) in human lung cancer.
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Academic Article
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Role of c-Met/phosphatidylinositol 3-kinase (PI3k)/Akt signaling in hepatocyte growth factor (HGF)-mediated lamellipodia formation, reactive oxygen species (ROS) generation, and motility of lung endothelial cells.
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Academic Article
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Role of PAX8 in the regulation of MET and RON receptor tyrosine kinases in non-small cell lung cancer.
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Academic Article
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Non-small cell lung cancer is susceptible to induction of DNA damage responses and inhibition of angiogenesis by telomere overhang oligonucleotides.
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Academic Article
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Multiple Endocrine Disruption by the MET/ALK Inhibitor Crizotinib in Patients With Non-small Cell Lung Cancer.
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Academic Article
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Dramatic antitumor effects of the dual MET/RON small-molecule inhibitor LY2801653 in non-small cell lung cancer.
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Academic Article
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Fibroblast growth factor signaling and inhibition in non-small cell lung cancer and their role in squamous cell tumors.
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Academic Article
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Nuclear epidermal growth factor receptor is a functional molecular target in triple-negative breast cancer.
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Academic Article
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PAX3 and FOXD3 Promote CXCR4 Expression in Melanoma.
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Academic Article
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Role played by paxillin and paxillin tyrosine phosphorylation in hepatocyte growth factor/sphingosine-1-phosphate-mediated reactive oxygen species generation, lamellipodia formation, and endothelial barrier function.
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Academic Article
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Oncoprotein ZNF322A transcriptionally deregulates alpha-adducin, cyclin D1 and p53 to promote tumor growth and metastasis in lung cancer.
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Academic Article
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RETRACTED: The receptor tyrosine kinase AXL mediates nuclear translocation of the epidermal growth factor receptor.
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Academic Article
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Refining epidermal growth factor receptor (EGFR) -inhibition-related rash (EIRR) phenotypes with a cetuximab (C) monotherapy stage of a phase II trial for non-small cell lung cancer (NSCLC).
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Academic Article
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MET in Lung Cancer: Biomarker Selection Based on Scientific Rationale.
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Academic Article
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B-Cell-Specific Diversion of Glucose Carbon Utilization Reveals a Unique Vulnerability in B Cell Malignancies.
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Academic Article
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Correction: Nuclear Epidermal Growth Factor Receptor Is a Functional Molecular Target in Triple-negative Breast Cancer.
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Academic Article
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SOX9: The master regulator of cell fate in breast cancer.
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Academic Article
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Inhibitors of the Transcription Factor STAT3 Decrease Growth and Induce Immune Response Genes in Models of Malignant Pleural Mesothelioma (MPM).
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Academic Article
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RLIP depletion induces apoptosis associated with inhibition of JAK2/STAT3 signaling in melanoma cells.
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Academic Article
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The Small Molecule BC-2059 Inhibits Wingless/Integrated (Wnt)-Dependent Gene Transcription in Cancer through Disruption of the Transducin ß-Like 1-ß-Catenin Protein Complex.
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Academic Article
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Exploring the Next Frontier in Non-Small-Cell Lung Cancer With High MET and Mutated Epidermal Growth Factor Receptor.
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Academic Article
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RLIP: A necessary transporter protein for translating oxidative stress into pro-obesity and pro-carcinogenic signaling.
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Concept
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PAX3 Transcription Factor
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Concept
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PAX8 Transcription Factor
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Concept
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PAX6 Transcription Factor
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Grant
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Role of c-Met in SCLC and Potential for Novel Therapy
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Grant
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Novel Targeted Therapy in Pancreatic Cancer
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Grant
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Studies of a Novel Therapeutic Target in Non-Small Cell Lung Cancer (NSCLC)
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Grant
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PAXILLIN--AN ONCOGENE ACTIVATED PROTEIN
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