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Proto-Oncogene Proteins c-kit
Steel factor induces tyrosine phosphorylation of CRKL and binding of CRKL to a complex containing c-kit, phosphatidylinositol 3-kinase, and p120(CBL).
Growth inhibition and modulation of kinase pathways of small cell lung cancer cell lines by the novel tyrosine kinase inhibitor STI 571.
Regulation of cellular proliferation, cytoskeletal function, and signal transduction through CXCR4 and c-Kit in small cell lung cancer cells.
Role of receptor tyrosine kinases in lung cancer.
Targeted molecules in small cell lung cancer.
Targeting c-Kit mutations: basic science to novel therapies.
Phase II study of imatinib in patients with small cell lung cancer.
Tyrosine kinase mutations in human cancer.
Mechanisms of metastasis as related to receptor tyrosine kinases in small-cell lung cancer.
Disruption of the EGFR E884-R958 ion pair conserved in the human kinome differentially alters signaling and inhibitor sensitivity.
Proto Oncogene Proteins c kit