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Search Results to Ravi Salgia

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One or more keywords matched the following items that are connected to Salgia, Ravi

Item TypeName
Concept Proto-Oncogene Proteins c-met
Academic Article Role of the hepatocyte growth factor receptor, c-Met, in oncogenesis and potential for therapeutic inhibition.
Academic Article Modulation of the c-Met/hepatocyte growth factor pathway in small cell lung cancer.
Academic Article Role of receptor tyrosine kinases in lung cancer.
Academic Article c-MET mutational analysis in small cell lung cancer: novel juxtamembrane domain mutations regulating cytoskeletal functions.
Academic Article Therapeutic targeting of the receptor tyrosine kinase Met.
Academic Article A selective small molecule c-MET Inhibitor, PHA665752, cooperates with rapamycin.
Academic Article Functional expression and mutations of c-Met and its therapeutic inhibition with SU11274 and small interfering RNA in non-small cell lung cancer.
Academic Article c-Met as a target for human cancer and characterization of inhibitors for therapeutic intervention.
Academic Article Activation of HGF/c-Met pathway contributes to the reactive oxygen species generation and motility of small cell lung cancer cells.
Academic Article A selective small molecule inhibitor of c-Met, PHA665752, inhibits tumorigenicity and angiogenesis in mouse lung cancer xenografts.
Academic Article c-Met inhibition.
Academic Article c-Met: structure, functions and potential for therapeutic inhibition.
Academic Article c-Met and hepatocyte growth factor: potential as novel targets in cancer therapy.
Academic Article PAX5 is expressed in small-cell lung cancer and positively regulates c-Met transcription.
Academic Article MET as a target for treatment of chest tumors.
Academic Article The MET receptor tyrosine kinase is a potential novel therapeutic target for head and neck squamous cell carcinoma.
Academic Article Expression and mutational analysis of MET in human solid cancers.
Academic Article MET pathway as a therapeutic target.
Academic Article Role of c-Met in cancer: emphasis on lung cancer.
Academic Article PAX6 is expressed in pancreatic cancer and actively participates in cancer progression through activation of the MET tyrosine kinase receptor gene.
Academic Article MET receptor tyrosine kinase.
Academic Article Ethnic differences and functional analysis of MET mutations in lung cancer.
Academic Article CBL is frequently altered in lung cancers: its relationship to mutations in MET and EGFR tyrosine kinases.
Academic Article c-Met overexpression is a prognostic factor in ovarian cancer and an effective target for inhibition of peritoneal dissemination and invasion.
Academic Article Rapid and dramatic radiographic and clinical response to an ALK inhibitor (crizotinib, PF02341066) in an ALK translocation-positive patient with non-small cell lung cancer.
Academic Article Lysophosphatidic acid modulates c-Met redistribution and hepatocyte growth factor/c-Met signaling in human bronchial epithelial cells through PKC delta and E-cadherin.
Academic Article Fyn is downstream of the HGF/MET signaling axis and affects cellular shape and tropism in PC3 cells.
Academic Article Downstream signalling and specific inhibition of c-MET/HGF pathway in small cell lung cancer: implications for tumour invasion.
Academic Article Effect of a c-Met-specific, ATP-competitive small-molecule inhibitor SU11274 on human ovarian carcinoma cell growth, motility, and invasion.
Academic Article Inhibition of MET receptor tyrosine kinase and its ligand hepatocyte growth factor.
Academic Article PAX3 and SOX10 activate MET receptor expression in melanoma.
Academic Article MET, HGF, EGFR, and PXN gene copy number in lung cancer using DNA extracts from FFPE archival samples and prognostic significance.
Academic Article MET and phosphorylated MET as potential biomarkers in lung cancer.
Academic Article Anaplastic lymphoma kinase inhibition in non-small-cell lung cancer.
Academic Article Inhibition of MET receptor tyrosine kinase and its ligand hepatocyte growth factor.
Academic Article MET amplification identifies a small and aggressive subgroup of esophagogastric adenocarcinoma with evidence of responsiveness to crizotinib.
Academic Article Tyrosine kinase mutations in human cancer.
Academic Article c-Met is a potentially new therapeutic target for treatment of human melanoma.
Academic Article Paxillin is a target for somatic mutations in lung cancer: implications for cell growth and invasion.
Academic Article Review of clinic trials: agents targeting c-Met.
Academic Article MET molecular mechanisms and therapies in lung cancer.
Academic Article Personalized treatment of lung cancer.
Academic Article A novel small molecule met inhibitor induces apoptosis in cells transformed by the oncogenic TPR-MET tyrosine kinase.
Academic Article Mechanisms of metastasis as related to receptor tyrosine kinases in small-cell lung cancer.
Academic Article CD44 regulates hepatocyte growth factor-mediated vascular integrity. Role of c-Met, Tiam1/Rac1, dynamin 2, and cortactin.
Academic Article C. elegans as a model organism for in vivo screening in cancer: effects of human c-Met in lung cancer affect C. elegans vulva phenotypes.
Academic Article Disruption of the EGFR E884-R958 ion pair conserved in the human kinome differentially alters signaling and inhibitor sensitivity.
Academic Article Expression patterns of PAX5, c-Met, and paxillin in neuroendocrine tumors of the lung.
Academic Article RON (MST1R) is a novel prognostic marker and therapeutic target for gastroesophageal adenocarcinoma.
Academic Article Activity of crizotinib (PF02341066), a dual mesenchymal-epithelial transition (MET) and anaplastic lymphoma kinase (ALK) inhibitor, in a non-small cell lung cancer patient with de novo MET amplification.
Academic Article Role of MetMAb (OA-5D5) in c-MET active lung malignancies.
Academic Article Durable complete response of metastatic gastric cancer with anti-Met therapy followed by resistance at recurrence.
Academic Article Lack of association of C-Met-N375S sequence variant with lung cancer susceptibility and prognosis.
Academic Article MET as a possible target for non-small-cell lung cancer.
Academic Article Critical role of S1PR1 and integrin ß4 in HGF/c-Met-mediated increases in vascular integrity.
Academic Article Initial clinical sensitivity and acquired resistance to MET inhibition in MET-mutated papillary renal cell carcinoma.
Academic Article Lipopolysaccharide-induced phosphorylation of c-Met tyrosine residue 1003 regulates c-Met intracellular trafficking and lung epithelial barrier function.
Academic Article Role of c-Met/phosphatidylinositol 3-kinase (PI3k)/Akt signaling in hepatocyte growth factor (HGF)-mediated lamellipodia formation, reactive oxygen species (ROS) generation, and motility of lung endothelial cells.
Academic Article Analysis of 1,115 patients tested for MET amplification and therapy response in the MD Anderson Phase I Clinic.
Academic Article MET and PI3K/mTOR as a potential combinatorial therapeutic target in malignant pleural mesothelioma.
Academic Article Role of PAX8 in the regulation of MET and RON receptor tyrosine kinases in non-small cell lung cancer.
Academic Article Multiple Endocrine Disruption by the MET/ALK Inhibitor Crizotinib in Patients With Non-small Cell Lung Cancer.
Academic Article Combined MET inhibition and topoisomerase I inhibition block cell growth of small cell lung cancer.
Academic Article Dramatic antitumor effects of the dual MET/RON small-molecule inhibitor LY2801653 in non-small cell lung cancer.
Academic Article Activation of MET via diverse exon 14 splicing alterations occurs in multiple tumor types and confers clinical sensitivity to MET inhibitors.
Academic Article MET as a drug target.
Academic Article C. elegans and mutants with chronic nicotine exposure as a novel model of cancer phenotype.
Academic Article Met gene amplification and protein hyperactivation is a mechanism of resistance to both first and third generation EGFR inhibitors in lung cancer treatment.
Academic Article PI3 Kinase Pathway and MET Inhibition is Efficacious in Malignant Pleural Mesothelioma.
Academic Article Expression and mutational analysis of c-CBL and its relationship to the MET receptor in head and neck squamous cell carcinoma.
Academic Article MET in Lung Cancer: Biomarker Selection Based on Scientific Rationale.
Academic Article Differential responsiveness of MET inhibition in non-small-cell lung cancer with altered CBL.
Academic Article Dose-escalation trial of the ALK, MET & ROS1 inhibitor, crizotinib, in patients with advanced cancer.
Academic Article Phase I Dose-Escalation and -Expansion Study of Telisotuzumab (ABT-700), an Anti-c-Met Antibody, in Patients with Advanced Solid Tumors.
Academic Article The promise of selective MET inhibitors in non-small cell lung cancer with MET exon 14 skipping.
Academic Article MET receptor in oncology: From biomarker to therapeutic target.
Academic Article Prolonged survival and response to tepotinib in a non-small-cell lung cancer patient with brain metastases harboring MET exon 14 mutation: a research report.

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  • Proto Oncogene Proteins c met