| Item Type | Name |
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Concept
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Adenosine Triphosphate
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Concept
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RNA, Viral
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Concept
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RNA
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Concept
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RNA Processing, Post-Transcriptional
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Concept
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RNA Interference
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Concept
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RNA-Binding Proteins
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Concept
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RNA, Messenger
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Concept
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Ubiquitin-Protein Ligases
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Concept
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RNA, Antisense
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Concept
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ATP-Binding Cassette Transporters
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Concept
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RNA, Small Interfering
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Concept
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Sequence Analysis, RNA
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Academic Article
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p210BCR/ABL induces formation of complexes containing focal adhesion proteins and the protooncogene product p120c-Cbl.
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Academic Article
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Steel factor induces tyrosine phosphorylation of CRKL and binding of CRKL to a complex containing c-kit, phosphatidylinositol 3-kinase, and p120(CBL).
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Academic Article
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Activation of hematopoietic growth factor signal transduction pathways by the human oncogene BCR/ABL.
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Academic Article
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The proto-oncogene product p120CBL and the adaptor proteins CRKL and c-CRK link c-ABL, p190BCR/ABL and p210BCR/ABL to the phosphatidylinositol-3' kinase pathway.
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Academic Article
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The BCR/ABL oncogene alters interaction of the adapter proteins CRKL and CRK with cellular proteins.
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Academic Article
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Tyrosine phosphorylation of the product of the c-cbl protooncogene is [corrected] induced after integrin stimulation.
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Academic Article
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Thrombopoietin induces activation of the phosphatidylinositol-3' kinase pathway and formation of a complex containing p85PI3K and the protooncoprotein p120CBL.
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Academic Article
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Differential expression and signaling of CBL and CBL-B in BCR/ABL transformed cells.
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Academic Article
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SHIP1, an SH2 domain containing polyinositol-5-phosphatase, regulates migration through two critical tyrosine residues and forms a novel signaling complex with DOK1 and CRKL.
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Academic Article
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Functional expression and mutations of c-Met and its therapeutic inhibition with SU11274 and small interfering RNA in non-small cell lung cancer.
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Academic Article
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PAX5 is expressed in small-cell lung cancer and positively regulates c-Met transcription.
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Academic Article
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The MET receptor tyrosine kinase is a potential novel therapeutic target for head and neck squamous cell carcinoma.
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Academic Article
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Functional analysis of c-Met/hepatocyte growth factor pathway in malignant pleural mesothelioma.
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Academic Article
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c-Met overexpression is a prognostic factor in ovarian cancer and an effective target for inhibition of peritoneal dissemination and invasion.
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Academic Article
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Lysophosphatidic acid modulates c-Met redistribution and hepatocyte growth factor/c-Met signaling in human bronchial epithelial cells through PKC delta and E-cadherin.
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Academic Article
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Fyn is downstream of the HGF/MET signaling axis and affects cellular shape and tropism in PC3 cells.
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Academic Article
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Downstream signalling and specific inhibition of c-MET/HGF pathway in small cell lung cancer: implications for tumour invasion.
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Academic Article
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Effect of a c-Met-specific, ATP-competitive small-molecule inhibitor SU11274 on human ovarian carcinoma cell growth, motility, and invasion.
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Academic Article
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Differential expression of RON in small and non-small cell lung cancers.
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Academic Article
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PAX3 and SOX10 activate MET receptor expression in melanoma.
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Academic Article
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Molecular cloning of human paxillin, a focal adhesion protein phosphorylated by P210BCR/ABL.
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Academic Article
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c-Met is a potentially new therapeutic target for treatment of human melanoma.
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Academic Article
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Paxillin is a target for somatic mutations in lung cancer: implications for cell growth and invasion.
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Academic Article
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Novel oncogenic mutations of CBL in human acute myeloid leukemia that activate growth and survival pathways depend on increased metabolism.
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Academic Article
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An E3 ubiquitin ligase: c-Cbl: a new therapeutic target of lung cancer.
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Academic Article
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Differential signaling after beta1 integrin ligation is mediated through binding of CRKL to p120(CBL) and p110(HEF1).
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Academic Article
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C. elegans as a model organism for in vivo screening in cancer: effects of human c-Met in lung cancer affect C. elegans vulva phenotypes.
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Academic Article
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RON (MST1R) is a novel prognostic marker and therapeutic target for gastroesophageal adenocarcinoma.
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Academic Article
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The EphB4 receptor tyrosine kinase promotes lung cancer growth: a potential novel therapeutic target.
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Academic Article
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Oral cavity tumors in younger patients show a poor prognosis and do not contain viral RNA.
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Academic Article
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Critical role of S1PR1 and integrin ß4 in HGF/c-Met-mediated increases in vascular integrity.
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Academic Article
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Lipopolysaccharide-induced phosphorylation of c-Met tyrosine residue 1003 regulates c-Met intracellular trafficking and lung epithelial barrier function.
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Academic Article
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AXL mediates resistance to cetuximab therapy.
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Academic Article
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AXL Is a Logical Molecular Target in Head and Neck Squamous Cell Carcinoma.
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Academic Article
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Novel EPHB4 Receptor Tyrosine Kinase Mutations and Kinomic Pathway Analysis in Lung Cancer.
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Academic Article
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Met gene amplification and protein hyperactivation is a mechanism of resistance to both first and third generation EGFR inhibitors in lung cancer treatment.
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Academic Article
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RETRACTED: The receptor tyrosine kinase AXL mediates nuclear translocation of the epidermal growth factor receptor.
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Academic Article
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TOPK (T-LAK cell-originated protein kinase) inhibitor exhibits growth suppressive effect on small cell lung cancer.
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Academic Article
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Camptothecin resistance is determined by the regulation of topoisomerase I degradation mediated by ubiquitin proteasome pathway.
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Academic Article
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Loss of H2B monoubiquitination is associated with poor-differentiation and enhanced malignancy of lung adenocarcinoma.
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Academic Article
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Differential responsiveness of MET inhibition in non-small-cell lung cancer with altered CBL.
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Academic Article
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2'-Hydroxyflavanone inhibits in vitro and in vivo growth of breast cancer cells by targeting RLIP76.
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Academic Article
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Metastasis of breast tumor cells to brain is suppressed by targeting RLIP alone and in combination with 2'-Hydroxyflavanone.
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Academic Article
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RLIP inhibition suppresses breast-to-lung metastasis.
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Academic Article
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RLIP: An existential requirement for breast carcinogenesis.
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Academic Article
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RLIP controls receptor-ligand signaling by regulating clathrin-dependent endocytosis.
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Academic Article
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SOX9: The master regulator of cell fate in breast cancer.
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Academic Article
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Targeting RLIP with CRISPR/Cas9 controls tumor growth.
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Academic Article
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Activating p53 function by targeting RLIP.
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Academic Article
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Prevention of mammary carcinogenesis in MMTV-neu mice by targeting RLIP.
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Academic Article
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RLIP depletion induces apoptosis associated with inhibition of JAK2/STAT3 signaling in melanoma cells.
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Academic Article
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RNA-based therapies: A cog in the wheel of lung cancer defense.
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Academic Article
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Evolution of core archetypal phenotypes in progressive high grade serous ovarian cancer.
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Academic Article
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Targeting the mercapturic acid pathway for the treatment of melanoma.
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Concept
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RNA, Long Noncoding
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Academic Article
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Enhancing carboplatin sensitivity in ovarian cancer cells by blocking the mercapturic acid pathway transporter.
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Academic Article
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RBM10 Mutation as a Potential Negative Prognostic/Predictive Biomarker to Therapy in Non-Small-Cell Lung Cancer.
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Academic Article
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Comprehensive investigation of long non-coding RNA HOTAIR polymorphisms and cancer risk: a current meta-analysis encompassing 96,458 participants.
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