Item Type | Name |
Concept
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Up-Regulation
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Concept
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Down-Regulation
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Concept
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Gene Expression Regulation, Enzymologic
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Concept
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Gene Expression Regulation, Neoplastic
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Academic Article
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The role of focal adhesion kinase binding in the regulation of tyrosine phosphorylation of paxillin.
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Academic Article
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The BCR/ABL oncogene alters the chemotactic response to stromal-derived factor-1alpha.
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Academic Article
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Differential expression and signaling of CBL and CBL-B in BCR/ABL transformed cells.
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Academic Article
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BAL is a novel risk-related gene in diffuse large B-cell lymphomas that enhances cellular migration.
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Academic Article
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Regulation of cellular proliferation, cytoskeletal function, and signal transduction through CXCR4 and c-Kit in small cell lung cancer cells.
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Academic Article
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Functional expression and mutations of c-Met and its therapeutic inhibition with SU11274 and small interfering RNA in non-small cell lung cancer.
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Academic Article
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Activation of HGF/c-Met pathway contributes to the reactive oxygen species generation and motility of small cell lung cancer cells.
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Academic Article
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Epidermal growth factor receptor mutations and susceptibility to targeted therapy in lung cancer.
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Academic Article
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Epidermal growth factor receptor - mediated signal transduction in the development and therapy of gliomas.
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Academic Article
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PAX5 is expressed in small-cell lung cancer and positively regulates c-Met transcription.
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Academic Article
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Activation of the PI3K/mTOR pathway by BCR-ABL contributes to increased production of reactive oxygen species.
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Academic Article
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EphA2 mutation in lung squamous cell carcinoma promotes increased cell survival, cell invasion, focal adhesions, and mammalian target of rapamycin activation.
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Academic Article
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PAX6 is expressed in pancreatic cancer and actively participates in cancer progression through activation of the MET tyrosine kinase receptor gene.
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Academic Article
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Fyn: a novel molecular target in cancer.
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Academic Article
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Fyn is downstream of the HGF/MET signaling axis and affects cellular shape and tropism in PC3 cells.
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Academic Article
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FYN is overexpressed in human prostate cancer.
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Academic Article
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Effect of a c-Met-specific, ATP-competitive small-molecule inhibitor SU11274 on human ovarian carcinoma cell growth, motility, and invasion.
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Academic Article
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Characterization of NOL7 gene point mutations, promoter methylation, and protein expression in cervical cancer.
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Academic Article
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PAX3 and SOX10 activate MET receptor expression in melanoma.
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Academic Article
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Melanoma proteoglycan modifies gene expression to stimulate tumor cell motility, growth, and epithelial-to-mesenchymal transition.
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Academic Article
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Novel functional germline variants in the VEGF receptor 2 gene and their effect on gene expression and microvessel density in lung cancer.
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Academic Article
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Targeting ALK: a promising strategy for the treatment of non-small cell lung cancer, non-Hodgkin's lymphoma, and neuroblastoma.
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Academic Article
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MET as a possible target for non-small-cell lung cancer.
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Academic Article
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Role of PAX8 in the regulation of MET and RON receptor tyrosine kinases in non-small cell lung cancer.
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Academic Article
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Non-small cell lung cancer is susceptible to induction of DNA damage responses and inhibition of angiogenesis by telomere overhang oligonucleotides.
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Academic Article
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Combined MET inhibition and topoisomerase I inhibition block cell growth of small cell lung cancer.
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Academic Article
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Dramatic antitumor effects of the dual MET/RON small-molecule inhibitor LY2801653 in non-small cell lung cancer.
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Academic Article
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AXL Is a Logical Molecular Target in Head and Neck Squamous Cell Carcinoma.
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Academic Article
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Novel EPHB4 Receptor Tyrosine Kinase Mutations and Kinomic Pathway Analysis in Lung Cancer.
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Academic Article
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PAX3 and FOXD3 Promote CXCR4 Expression in Melanoma.
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Academic Article
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Effective growth-suppressive activity of maternal embryonic leucine-zipper kinase (MELK) inhibitor against small cell lung cancer.
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Academic Article
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Met gene amplification and protein hyperactivation is a mechanism of resistance to both first and third generation EGFR inhibitors in lung cancer treatment.
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Academic Article
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Expression and mutational analysis of c-CBL and its relationship to the MET receptor in head and neck squamous cell carcinoma.
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Academic Article
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Camptothecin resistance is determined by the regulation of topoisomerase I degradation mediated by ubiquitin proteasome pathway.
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Academic Article
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Loss of H2B monoubiquitination is associated with poor-differentiation and enhanced malignancy of lung adenocarcinoma.
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Academic Article
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2'-Hydroxyflavanone induced changes in the proteomic profile of breast cancer cells.
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Academic Article
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EphB4: A promising target for upper aerodigestive malignancies.
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Academic Article
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2'-Hydroxyflavanone inhibits in vitro and in vivo growth of breast cancer cells by targeting RLIP76.
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Academic Article
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The brigatinib experience: a new generation of therapy for ALK-positive non-small-cell lung cancer.
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Academic Article
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Dose-escalation trial of the ALK, MET & ROS1 inhibitor, crizotinib, in patients with advanced cancer.
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Academic Article
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Therapeutic targeting of miRNA-216b in cancer.
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Academic Article
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AXL Mediates Cetuximab and Radiation Resistance Through Tyrosine 821 and the c-ABL Kinase Pathway in Head and Neck Cancer.
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Academic Article
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Targeting FTO Suppresses Cancer Stem Cell Maintenance and Immune Evasion.
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Academic Article
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Activating p53 function by targeting RLIP.
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Academic Article
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The improbable targeted therapy: KRAS as an emerging target in non-small cell lung cancer (NSCLC).
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Academic Article
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MicroRNA-1: Diverse role of a small player in multiple cancers.
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Academic Article
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Essential role of the histone lysine demethylase KDM4A in the biology of malignant pleural mesothelioma (MPM).
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Academic Article
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Protein Phosphatase 2A as a Therapeutic Target in Small Cell Lung Cancer.
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Academic Article
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MicroRNA-1 attenuates the growth and metastasis of small cell lung cancer through CXCR4/FOXM1/RRM2 axis.
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