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Missiakas, Dominique
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overview Dr. Missiakas’s research program examines the Gram-positive pathogens Staphylococcus aureus and Bacillus anthracis. This program seeks to appreciate the biogenesis of the envelope of these microorganisms as well as the secretion of their virulence factors and host pathways targeted by these pathogens.
One or more keywords matched the following items that are connected to Missiakas, Dominique
Item TypeName
Concept Methicillin-Resistant Staphylococcus aureus
Concept Staphylococcus
Concept Staphylococcus aureus
Academic Article Passage of heme-iron across the envelope of Staphylococcus aureus.
Academic Article Structures of sortase B from Staphylococcus aureus and Bacillus anthracis reveal catalytic amino acid triad in the active site.
Academic Article EsxA and EsxB are secreted by an ESAT-6-like system that is required for the pathogenesis of Staphylococcus aureus infections.
Academic Article The membrane-associated lipoprotein-9 GmpC from Staphylococcus aureus binds the dipeptide GlyMet via side chain interactions.
Academic Article Staphylococcus aureus virulence genes identified by bursa aurealis mutagenesis and nematode killing.
Academic Article Host defenses against Staphylococcus aureus infection require recognition of bacterial lipoproteins.
Academic Article EsaC substrate for the ESAT-6 secretion pathway and its role in persistent infections of Staphylococcus aureus.
Academic Article Nontoxigenic protein A vaccine for methicillin-resistant Staphylococcus aureus infections in mice.
Academic Article EsaD, a secretion factor for the Ess pathway in Staphylococcus aureus.
Academic Article Identifying protective antigens of Staphylococcus aureus, a pathogen that suppresses host immune responses.
Academic Article Genetic requirements for Staphylococcus aureus abscess formation and persistence in host tissues.
Academic Article Enzymatic properties of Staphylococcus aureus adenosine synthase (AdsA).
Academic Article Staphylococcus aureus secretes coagulase and von Willebrand factor binding protein to modify the coagulation cascade and establish host infections.
Academic Article Preventing Staphylococcus aureus sepsis through the inhibition of its agglutination in blood.
Academic Article Generating a collection of insertion mutations in the Staphylococcus aureus genome using bursa aurealis.
Academic Article Characterization of EssB, a protein required for secretion of ESAT-6 like proteins in Staphylococcus aureus.
Academic Article Golden pigment production and virulence gene expression are affected by metabolisms in Staphylococcus aureus.
Academic Article A new oxidative sensing and regulation pathway mediated by the MgrA homologue SarZ in Staphylococcus aureus.
Academic Article A play in four acts: Staphylococcus aureus abscess formation.
Academic Article Protein A-specific monoclonal antibodies and prevention of Staphylococcus aureus disease in mice.
Academic Article Expression of multidrug resistance efflux pump gene norA is iron responsive in Staphylococcus aureus.
Academic Article LytN, a murein hydrolase in the cross-wall compartment of Staphylococcus aureus, is involved in proper bacterial growth and envelope assembly.
Academic Article Exploring Staphylococcus aureus pathways to disease for vaccine development.
Academic Article Coagulases as determinants of protective immune responses against Staphylococcus aureus.
Academic Article Signal peptides direct surface proteins to two distinct envelope locations of Staphylococcus aureus.
Academic Article Contribution of coagulases towards Staphylococcus aureus disease and protective immunity.
Academic Article Abscess formation and alpha-hemolysin induced toxicity in a mouse model of Staphylococcus aureus peritoneal infection.
Academic Article Staphylococcus aureus mutants with increased lysostaphin resistance.
Academic Article Staphylococcus aureus synthesizes adenosine to escape host immune responses.
Academic Article IsdA and IsdB antibodies protect mice against Staphylococcus aureus abscess formation and lethal challenge.
Academic Article ABI domain-containing proteins contribute to surface protein display and cell division in Staphylococcus aureus.
Academic Article Recurrent infections and immune evasion strategies of Staphylococcus aureus.
Academic Article Growth and laboratory maintenance of Staphylococcus aureus.
Academic Article Small molecule inhibitor of lipoteichoic acid synthesis is an antibiotic for Gram-positive bacteria.
Academic Article The role of staphylothrombin-mediated fibrin deposition in catheter-related Staphylococcus aureus infections.
Academic Article Vaccine protection of leukopenic mice against Staphylococcus aureus bloodstream infection.
Academic Article Multiple ligands of von Willebrand factor-binding protein (vWbp) promote Staphylococcus aureus clot formation in human plasma.
Academic Article Protein A-neutralizing monoclonal antibody protects neonatal mice against Staphylococcus aureus.
Academic Article Role of protein A in the evasion of host adaptive immune responses by Staphylococcus aureus.
Academic Article Protein A suppresses immune responses during Staphylococcus aureus bloodstream infection in guinea pigs.
Academic Article Secretion of atypical protein substrates by the ESAT-6 secretion system of Staphylococcus aureus.
Academic Article Staphylococcus aureus degrades neutrophil extracellular traps to promote immune cell death.
Academic Article N-acetylglucosaminylation of serine-aspartate repeat proteins promotes Staphylococcus aureus bloodstream infection.
Academic Article Release of protein A from the cell wall of Staphylococcus aureus.
Academic Article Mouse models for infectious diseases caused by Staphylococcus aureus.
Academic Article The capsular polysaccharide of Staphylococcus aureus is attached to peptidoglycan by the LytR-CpsA-Psr (LCP) family of enzymes.
Academic Article Staphylococcus aureus mutants lacking the LytR-CpsA-Psr family of enzymes release cell wall teichoic acids into the extracellular medium.
Academic Article The giant protein Ebh is a determinant of Staphylococcus aureus cell size and complement resistance.
Academic Article Genetic manipulation of Staphylococcus aureus.
Academic Article Adhesion of Staphylococcus aureus to the vessel wall under flow is mediated by von Willebrand factor-binding protein.
Academic Article Staphylococcal manipulation of host immune responses.
Academic Article SagB Glucosaminidase Is a Determinant of Staphylococcus aureus Glycan Chain Length, Antibiotic Susceptibility, and Protein Secretion.
Academic Article Antibodies against a secreted product of Staphylococcus aureus trigger phagocytic killing.
Academic Article Pathogenesis of Staphylococcus aureus Bloodstream Infections.
Academic Article Peptidoglycan-linked protein A promotes T cell-dependent antibody expansion during Staphylococcus aureus infection.
Academic Article Contribution of Staphylococcus aureus Coagulases and Clumping Factor A to Abscess Formation in a Rabbit Model of Skin and Soft Tissue Infection.
Academic Article Staphylococcus aureus vaccines: Deviating from the carol.
Academic Article EssE Promotes Staphylococcus aureus ESS-Dependent Protein Secretion To Modify Host Immune Responses during Infection.
Academic Article EssD, a Nuclease Effector of the Staphylococcus aureus ESS Pathway.
Academic Article Pathogenic conversion of coagulase-negative staphylococci.
Academic Article Clumping factor A, von Willebrand factor-binding protein and von Willebrand factor anchor Staphylococcus aureus to the vessel wall.
Academic Article A novel STK1-targeted small-molecule as an "antibiotic resistance breaker" against multidrug-resistant Staphylococcus aureus.
Academic Article Staphylococcus aureus targets the purine salvage pathway to kill phagocytes.
Academic Article EssH Peptidoglycan Hydrolase Enables Staphylococcus aureus Type VII Secretion across the Bacterial Cell Wall Envelope.
Academic Article Isolation of a Membrane Protein Complex for Type VII Secretion in Staphylococcus aureus.
Academic Article The transmembrane domain of the Staphylococcus aureus ESAT-6 component EssB mediates interaction with the integral membrane protein EsaA, facilitating partially regulated secretion in a heterologous host.
Academic Article Marginal role of von Willebrand factor-binding protein and coagulase in the initiation of endocarditis in rats with catheter-induced aortic vegetations.
Academic Article Staphylococcal Protein A Contributes to Persistent Colonization of Mice with Staphylococcus aureus.
Academic Article Septal secretion of protein A in Staphylococcus aureus requires SecA and lipoteichoic acid synthesis.
Academic Article Staphylococcus aureus Decolonization of Mice With Monoclonal Antibody Neutralizing Protein A.
Academic Article Sortases, Surface Proteins, and Their Roles in Staphylococcus aureus Disease and Vaccine Development.
Academic Article Staphylococcus aureus TarP: A Brick in the Wall or Rosetta Stone?
Academic Article Staphylococcus aureus alpha-hemolysin impairs corneal epithelial wound healing and promotes intracellular bacterial invasion.
Academic Article Staphylococcus aureus endocarditis: distinct mechanisms of bacterial adhesion to damaged and inflamed heart valves.
Academic Article Staphylococcal Protein Secretion and Envelope Assembly.
Academic Article Staphylococcus aureus Exploits the Host Apoptotic Pathway To Persist during Infection.
Academic Article Rapid pathogen identification and antimicrobial susceptibility testing in in vitro endophthalmitis with matrix assisted laser desorption-ionization Time-of-Flight Mass Spectrometry and VITEK 2 without prior culture.
Academic Article FmhA and FmhC of Staphylococcus aureus incorporate serine residues into peptidoglycan cross-bridges.
Academic Article Glycosylation-dependent opsonophagocytic activity of staphylococcal protein A antibodies.
Academic Article The Expression of von Willebrand Factor-Binding Protein Determines Joint-Invading Capacity of Staphylococcus aureus, a Core Mechanism of Septic Arthritis.
Academic Article Selective Host Cell Death by Staphylococcus aureus: A Strategy for Bacterial Persistence.
Academic Article Staphylococcus aureus vWF-binding protein triggers a strong interaction between clumping factor A and host vWF.
Academic Article Peptidoglycan Contribution to the B Cell Superantigen Activity of Staphylococcal Protein A.
Academic Article A protein A based Staphylococcus aureus vaccine with improved safety.
Academic Article Corrigendum to: Staphylococcus aureus Decolonization of Mice With Monoclonal Antibody Neutralizing Protein A.
Academic Article Engineered human antibodies for the opsonization and killing of Staphylococcus aureus.
Academic Article Toward Optimization of a Rabbit Model of Staphylococcus aureus (USA300) Skin and Soft Tissue Infection.
Academic Article Contribution of the EssC ATPase to the assembly of the type 7b secretion system in Staphylococcus aureus.
Academic Article Neutrophils Protect Against Staphylococcus aureus Endocarditis Progression Independent of Extracellular Trap Release.
Grant Surface Proteins of Gram-Positive Bacteria
Grant Advanced development of a vaccine candidate for Staphylococcus aureus infection and colonization
Academic Article Immunoglobulin G subclasses confer protection against Staphylococcus aureus bloodstream dissemination through distinct mechanisms in mouse models.
Academic Article The Type 7b Secretion System of S. aureus and Its Role in Colonization and Systemic Infection.
Academic Article A humanized monoclonal antibody targeting protein a promotes opsonophagocytosis of Staphylococcus aureus in human umbilical cord blood.
Academic Article Protein coopted from a phage restriction system dictates orthogonal cell division plane selection in Staphylococcus aureus.
Academic Article Processing of LtaS restricts LTA assembly and YSIRK preprotein trafficking into Staphylococcus aureus cross-walls.
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