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Bell, Graeme

One or more keywords matched the following items that are connected to Bell, Graeme

Item Type	Name
Concept	Blood Glucose
Concept	Glucose-6-Phosphatase
Concept	Glucose Tolerance Test
Concept	Glucose Clamp Technique
Concept	Glucose Intolerance
Concept	Glucose Transporter Type 2
Concept	Glucose Transporter Type 1
Concept	Glucose
Concept	Glucose Transporter Type 4
Concept	Glucose Transporter Type 5
Academic Article	Hormonal/metabolic regulation of the human GLUT4/muscle-fat facilitative glucose transporter gene in transgenic mice.
Academic Article	Human GLUT4/muscle-fat glucose-transporter gene. Characterization and genetic variation.
Academic Article	Seminars in Medicine of the Beth Israel Hospital, Boston. Non-insulin-dependent diabetes mellitus - a genetically programmed failure of the beta cell to compensate for insulin resistance.
Academic Article	Novel MODY3 mutations in the hepatocyte nuclear factor-1alpha gene: evidence for a hyperexcitability of pancreatic beta-cells to intravenous secretagogues in a glucose-tolerant carrier of a P447L mutation.
Academic Article	NIDDM is associated with loss of pancreatic beta-cell L-type Ca2+ channel activity.
Academic Article	Mammalian facilitative glucose transporters: evidence for similar substrate recognition sites in functionally monomeric proteins.
Academic Article	Changes in pancreatic islet glucokinase and hexokinase activities with increasing age, obesity, and the onset of diabetes.
Academic Article	Hepatic function in a family with a nonsense mutation (R154X) in the hepatocyte nuclear factor-4alpha/MODY1 gene.
Academic Article	Molecular analysis of the fructose transporter gene (GLUT5) in isolated fructose malabsorption.
Academic Article	Altered insulin secretory responses to glucose in diabetic and nondiabetic subjects with mutations in the diabetes susceptibility gene MODY3 on chromosome 12.
Academic Article	Maturity onset diabetes of the young (MODY).
Academic Article	Expression and regulation of the human GLUT4/muscle-fat facilitative glucose transporter gene in transgenic mice.
Academic Article	A calpain-10 gene polymorphism is associated with reduced muscle mRNA levels and insulin resistance.
Academic Article	Molecular mechanisms and clinical pathophysiology of maturity-onset diabetes of the young.
Academic Article	Relationship of insulin receptor substrate-1 and -2 genotypes to phenotypic features of polycystic ovary syndrome.
Academic Article	Reduced pancreatic polypeptide response to hypoglycemia and amylin response to arginine in subjects with a mutation in the HNF-4alpha/MODY1 gene.
Academic Article	Neonatal diabetes mellitus due to complete glucokinase deficiency.
Academic Article	Calpains play a role in insulin secretion and action.
Academic Article	Improved glucose tolerance and insulin sensitivity after electrical stimulation-assisted cycling in people with spinal cord injury.
Academic Article	Relationship of calpain-10 genotype to phenotypic features of polycystic ovary syndrome.
Academic Article	Variants within the calpain-10 gene on chromosome 2q37 (NIDDM1) and relationships to type 2 diabetes, insulin resistance, and impaired acute insulin secretion among Scandinavian Caucasians.
Academic Article	A 48-hour exposure of pancreatic islets to calpain inhibitors impairs mitochondrial fuel metabolism and the exocytosis of insulin.
Academic Article	Transgenic mice with green fluorescent protein-labeled pancreatic beta -cells.
Academic Article	RyR2 and calpain-10 delineate a novel apoptosis pathway in pancreatic islets.
Academic Article	Treatment of hyperglycemia in a 7-year-old child diagnosed with neonatal diabetes.
Academic Article	Anti-diabetic effect of ginsenoside Re in ob/ob mice.
Academic Article	Calpain system regulates muscle mass and glucose transporter GLUT4 turnover.
Academic Article	Phenotypic heterogeneity between different mutations of MODY subtypes and within MODY pedigrees.
Academic Article	Permanent neonatal diabetes due to mutations in KCNJ11 encoding Kir6.2: patient characteristics and initial response to sulfonylurea therapy.
Academic Article	Noninvasive monitoring of changes in pancreatic beta-cell mass by bioluminescent imaging in MIP-luc transgenic mice.
Academic Article	Sustained expression of hepatocyte nuclear factor-6 leads to loss of pancreatic beta-cells by apoptosis.
Academic Article	Association of the (AU)AT-rich element polymorphism in PPP1R3 with hormonal and metabolic features of polycystic ovary syndrome.
Academic Article	From clinicogenetic studies of maturity-onset diabetes of the young to unraveling complex mechanisms of glucokinase regulation.
Academic Article	Kir6.2 variant E23K increases ATP-sensitive K+ channel activity and is associated with impaired insulin release and enhanced insulin sensitivity in adults with normal glucose tolerance.
Academic Article	Variation in the perilipin gene (PLIN) affects glucose and lipid metabolism in non-Hispanic white women with and without polycystic ovary syndrome.
Academic Article	Common polymorphisms of calpain-10 are associated with abdominal obesity in subjects at high risk of type 2 diabetes.
Academic Article	Glycemic control promotes pancreatic beta-cell regeneration in streptozotocin-induced diabetic mice.
Academic Article	Calpain-10 gene and protein expression in human skeletal muscle: effect of acute lipid-induced insulin resistance and type 2 diabetes.
Academic Article	TCF7L2 variant rs7903146 affects the risk of type 2 diabetes by modulating incretin action.
Academic Article	Characterization of Japanese families with early-onset type 2 (non-insulin dependent) diabetes mellitus and screening for mutations in the glucokinase and mitochondrial tRNA(Leu(UUR)) genes.
Academic Article	Identification of two novel amino acid polymorphisms in beta-cell/liver (GLUT2) glucose transporter in Japanese subjects.
Academic Article	Insulin secretory abnormalities in subjects with hyperglycemia due to glucokinase mutations.
Academic Article	Evolution of beta-cell dysfunction in the male Zucker diabetic fatty rat.
Academic Article	Clinical characteristics of subjects with a missense mutation in glucokinase.
Academic Article	Expression of calcium channel mRNAs in rat pancreatic islets and downregulation after glucose infusion.
Academic Article	In vitro processing and secretion of mutant insulin proteins that cause permanent neonatal diabetes.
Academic Article	Organization of the human GLUT2 (pancreatic beta-cell and hepatocyte) glucose transporter gene.
Academic Article	Differential effects of overexpressed glucokinase and hexokinase I in isolated islets. Evidence for functional segregation of the high and low Km enzymes.
Academic Article	Alterations in TCF7L2 expression define its role as a key regulator of glucose metabolism.
Academic Article	Genetic contribution of polymorphism of the GLUT1 and GLUT4 genes to the susceptibility to type 2 (non-insulin-dependent) diabetes mellitus in different populations.
Academic Article	Variation in the calpain-10 gene affects blood glucose levels in the British population.
Academic Article	Organ alchemy: producing insulin in the liver.
Academic Article	Insulin promoter factor-1 mutations and diabetes in Trinidad: identification of a novel diabetes-associated mutation (E224K) in an Indo-Trinidadian family.
Academic Article	Abnormal insulin secretion, not insulin resistance, is the genetic or primary defect of MODY in the RW pedigree.
Academic Article	5-amino-imidazole carboxamide riboside acutely potentiates glucose-stimulated insulin secretion from mouse pancreatic islets by KATP channel-dependent and -independent pathways.
Academic Article	Altered insulin secretory responses to glucose in subjects with a mutation in the MODY1 gene on chromosome 20.
Academic Article	Regulation of expression of the human fructose transporter (GLUT5) by cyclic AMP.
Academic Article	Molecular model of human beta-cell glucokinase built by analogy to the crystal structure of yeast hexokinase B.
Academic Article	Type 2 (non-insulin-dependent) diabetes mellitus associated with a mutation of the glucokinase gene in a Japanese family.
Academic Article	Sequence, tissue distribution, and functional characterization of the rat fructose transporter GLUT5.
Academic Article	The advantage of sex in evolving yeast populations.
Academic Article	Evidence of non-pancreatic beta cell-dependent roles of Tcf7l2 in the regulation of glucose metabolism in mice.
Academic Article	Identification and functional characterization of G6PC2 coding variants influencing glycemic traits define an effector transcript at the G6PC2-ABCB11 locus.
Academic Article	Remifentanil vs fentanyl/morphine for pain and stress control during pediatric cardiac surgery.
Grant	MOLECULAR MECHANISMS/BETA CELL DYSFUNCTION IN DIABETES
Grant	Functional follow-up of the association between TCF7L2 and T2D

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Glucose