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McLeod, Rima
One or more keywords matched the following items that are connected to
McLeod, Rima
Item Type
Name
Concept
Alcohol Oxidoreductases
Concept
Oxidoreductases
Concept
NAD
Concept
Tetrahydrofolate Dehydrogenase
Concept
Enoyl-(Acyl-Carrier-Protein) Reductase (NADH)
Academic Article
Expression, purification and crystallization of the Plasmodium falciparum enoyl reductase.
Academic Article
Delivery of antimicrobials into parasites.
Academic Article
Triclosan inhibits the growth of Plasmodium falciparum and Toxoplasma gondii by inhibition of apicomplexan Fab I.
Academic Article
Evidence for mitochondrial-derived alternative oxidase in the apicomplexan parasite Cryptosporidium parvum: a potential anti-microbial agent target.
Academic Article
Triazine Inhibits Toxoplasma gondii tachyzoites in vitro and in vivo.
Academic Article
Expression, purification and preliminary crystallographic analysis of the Toxoplasma gondii enoyl reductase.
Academic Article
Studies of Toxoplasma gondii and Plasmodium falciparum enoyl acyl carrier protein reductase and implications for the development of antiparasitic agents.
Academic Article
Novel triazine JPC-2067-B inhibits Toxoplasma gondii in vitro and in vivo.
Academic Article
Molecular target validation, antimicrobial delivery, and potential treatment of Toxoplasma gondii infections.
Academic Article
Evolutionary origins of the eukaryotic shikimate pathway: gene fusions, horizontal gene transfer, and endosymbiotic replacements.
Academic Article
Design, synthesis, and biological activity of diaryl ether inhibitors of Toxoplasma gondii enoyl reductase.
Academic Article
Modification of triclosan scaffold in search of improved inhibitors for enoyl-acyl carrier protein (ACP) reductase in Toxoplasma gondii.
Academic Article
Development of a triclosan scaffold which allows for adaptations on both the A- and B-ring for transport peptides.
Academic Article
The benzimidazole based drugs show good activity against T. gondii but poor activity against its proposed enoyl reductase enzyme target.
Academic Article
Discrimination of potent inhibitors of Toxoplasma gondii enoyl-acyl carrier protein reductase by a thermal shift assay.
Academic Article
Identification and development of novel inhibitors of Toxoplasma gondii enoyl reductase.
Grant
Optimizing Inhibitors of T. gondii ENR
Search Criteria
Enoyl
Acyl Carrier Protein
Reductase
NADH