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Thirman, Michael J.
One or more keywords matched the following items that are connected to Thirman, Michael J.
Item TypeName
Concept Histone-Lysine N-Methyltransferase
Academic Article Analysis of the t(6;11)(q27;q23) in leukemia shows a consistent breakpoint in AF6 in three patients and in the ML-2 cell line.
Academic Article Distribution of 11q23 breakpoints within the MLL breakpoint cluster region in de novo acute leukemia and in treatment-related acute myeloid leukemia: correlation with scaffold attachment regions and topoisomerase II consensus binding sites.
Academic Article Chromatin-related properties of CBP fused to MLL generate a myelodysplastic-like syndrome that evolves into myeloid leukemia.
Academic Article Retrovirus-mediated gene transfer of MLL-ELL transforms primary myeloid progenitors and causes acute myeloid leukemias in mice.
Academic Article ELL-associated factor 2 (EAF2), a functional homolog of EAF1 with alternative ELL binding properties.
Academic Article The elongation domain of ELL is dispensable but its ELL-associated factor 1 interaction domain is essential for MLL-ELL-induced leukemogenesis.
Academic Article The elongation factor ELL (eleven-nineteen lysine-rich leukemia) is a selective coregulator for steroid receptor functions.
Academic Article Loss of MLL PHD finger 3 is necessary for MLL-ENL-induced hematopoietic stem cell immortalization.
Academic Article Gene mutations, epigenetic dysregulation, and personalized therapy in myeloid neoplasia: are we there yet?
Academic Article Cloning of ELL, a gene that fuses to MLL in a t(11;19)(q23;p13.1) in acute myeloid leukemia.
Academic Article DNA rearrangements and altered transcripts of the MLL gene in a human T-ALL cell line Karpas 45 with a t(X;11) (q13;q23) translocation.
Academic Article The human MLL gene: nucleotide sequence, homology to the Drosophila trx zinc-finger domain, and alternative splicing.
Academic Article Detection of MLL gene rearrangements in adult acute lymphoblastic leukemia. A Cancer and Leukemia Group B study.
Academic Article Abnormalities of chromosome band 11q23 and the MLL gene in pediatric myelomonocytic and monoblastic leukemias. Identification of the t(9;11) as an indicator of long survival.
Academic Article Consistent deregulation of gene expression between human and murine MLL rearrangement leukemias.
Academic Article Detection of 11q23/MLL rearrangements in infant leukemias with fluorescence in situ hybridization and molecular analysis.
Academic Article EAF1, a novel ELL-associated factor that is delocalized by expression of the MLL-ELL fusion protein.
Academic Article MLL fusion proteins preferentially regulate a subset of wild-type MLL target genes in the leukemic genome.
Academic Article Instructive Role of MLL-Fusion Proteins Revealed by a Model of t(4;11) Pro-B Acute Lymphoblastic Leukemia.
Academic Article Paradoxical Effects of MLL Paralogs in MLL-Rearranged Leukemia.
Academic Article The menin inhibitor revumenib in KMT2A-rearranged or NPM1-mutant leukaemia.
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  • Histone Lysine N Methyltransferase