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Search Results to Michael J. Thirman

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One or more keywords matched the following items that are connected to Thirman, Michael J.

Item TypeName
Concept Oncogenes
Concept Proto-Oncogene Proteins
Concept Oncogene Proteins, Fusion
Concept Oncogene Proteins v-myb
Concept Proto-Oncogene Proteins c-pim-1
Concept Proto-Oncogene Proteins c-kit
Concept Proto-Oncogenes
Concept Proto-Oncogene Proteins c-bcl-6
Academic Article Analysis of the t(6;11)(q27;q23) in leukemia shows a consistent breakpoint in AF6 in three patients and in the ML-2 cell line.
Academic Article Distribution of 11q23 breakpoints within the MLL breakpoint cluster region in de novo acute leukemia and in treatment-related acute myeloid leukemia: correlation with scaffold attachment regions and topoisomerase II consensus binding sites.
Academic Article The human programmed cell death-2 (PDCD2) gene is a target of BCL6 repression: implications for a role of BCL6 in the down-regulation of apoptosis.
Academic Article Chromatin-related properties of CBP fused to MLL generate a myelodysplastic-like syndrome that evolves into myeloid leukemia.
Academic Article Retrovirus-mediated gene transfer of MLL-ELL transforms primary myeloid progenitors and causes acute myeloid leukemias in mice.
Academic Article ELL and EAF1 are Cajal body components that are disrupted in MLL-ELL leukemia.
Academic Article ELL-associated factor 2 (EAF2), a functional homolog of EAF1 with alternative ELL binding properties.
Academic Article The elongation domain of ELL is dispensable but its ELL-associated factor 1 interaction domain is essential for MLL-ELL-induced leukemogenesis.
Academic Article The human BCL6 transgene promotes the development of lymphomas in the mouse.
Academic Article The elongation factor ELL (eleven-nineteen lysine-rich leukemia) is a selective coregulator for steroid receptor functions.
Academic Article Repression of the PDCD2 gene by BCL6 and the implications for the pathogenesis of human B and T cell lymphomas.
Academic Article Gene mutations, epigenetic dysregulation, and personalized therapy in myeloid neoplasia: are we there yet?
Academic Article Cloning of ELL, a gene that fuses to MLL in a t(11;19)(q23;p13.1) in acute myeloid leukemia.
Academic Article PDCD2, a protein whose expression is repressed by BCL6, induces apoptosis in human cells by activation of the caspase cascade.
Academic Article PIM1 gene cooperates with human BCL6 gene to promote the development of lymphomas.
Academic Article DNA rearrangements and altered transcripts of the MLL gene in a human T-ALL cell line Karpas 45 with a t(X;11) (q13;q23) translocation.
Academic Article The human MLL gene: nucleotide sequence, homology to the Drosophila trx zinc-finger domain, and alternative splicing.
Academic Article Detection of MLL gene rearrangements in adult acute lymphoblastic leukemia. A Cancer and Leukemia Group B study.
Academic Article Abnormalities of chromosome band 11q23 and the MLL gene in pediatric myelomonocytic and monoblastic leukemias. Identification of the t(9;11) as an indicator of long survival.
Academic Article Consistent deregulation of gene expression between human and murine MLL rearrangement leukemias.
Academic Article Detection of 11q23/MLL rearrangements in infant leukemias with fluorescence in situ hybridization and molecular analysis.
Academic Article EAF1, a novel ELL-associated factor that is delocalized by expression of the MLL-ELL fusion protein.
Academic Article MLL fusion proteins preferentially regulate a subset of wild-type MLL target genes in the leukemic genome.
Academic Article GFI1B, EVI5, MYB--additional genes that cooperate with the human BCL6 gene to promote the development of lymphomas.
Academic Article Instructive Role of MLL-Fusion Proteins Revealed by a Model of t(4;11) Pro-B Acute Lymphoblastic Leukemia.
Academic Article The full transforming capacity of MLL-Af4 is interlinked with lymphoid lineage commitment.
Academic Article Quercetin Therapy for Selected Patients with PIM1 Kinase-Positive Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma: A Pilot Study.
Academic Article Cytokine-Regulated Phosphorylation and Activation of TET2 by JAK2 in Hematopoiesis.

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  • Oncogenes