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Gupta, Mahesh P.
One or more keywords matched the following properties of
Gupta, Mahesh P.
Property
Value
keywords
Heart Failure, cardiac aging, Sirtuins, diabetes, mitochondria, Sepsis, Cachexia
One or more keywords matched the following items that are connected to
Gupta, Mahesh P.
Item Type
Name
Concept
Mitochondria, Heart
Concept
Mitochondria
Academic Article
SIRT3 is a stress-responsive deacetylase in cardiomyocytes that protects cells from stress-mediated cell death by deacetylation of Ku70.
Academic Article
Mitochondrial SIRT3 and heart disease.
Academic Article
SIRT3 deacetylates and activates OPA1 to regulate mitochondrial dynamics during stress.
Academic Article
Honokiol blocks and reverses cardiac hypertrophy in mice by activating mitochondrial Sirt3.
Academic Article
Sirt3 protects mitochondrial DNA damage and blocks the development of doxorubicin-induced cardiomyopathy in mice.
Academic Article
Honokiol, an activator of Sirtuin-3 (SIRT3) preserves mitochondria and protects the heart from doxorubicin-induced cardiomyopathy in mice.
Grant
Exploring roles of sirtuins in protecting diabetic hearts
Grant
Blocking cardiac toxicity of anticancer drugs
Academic Article
The nuclear and mitochondrial sirtuins, Sirt6 and Sirt3, regulate each other's activity and protect the heart from developing obesity-mediated diabetic cardiomyopathy.
Search Criteria
Mitochondria