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One or more keywords matched the following items that are connected to Gupta, Mahesh P.
Item TypeName
Concept Myocardium
Academic Article Increased expression of alternatively spliced dominant-negative isoform of SRF in human failing hearts.
Academic Article Calcium/calmodulin-dependent protein kinase activates serum response factor transcription activity by its dissociation from histone deacetylase, HDAC4. Implications in cardiac muscle gene regulation during hypertrophy.
Academic Article Poly(ADP-ribose) polymerase-1-deficient mice are protected from angiotensin II-induced cardiac hypertrophy.
Academic Article Concurrent opposite effects of trichostatin A, an inhibitor of histone deacetylases, on expression of alpha-MHC and cardiac tubulins: implication for gain in cardiac muscle contractility.
Academic Article HDAC4 and PCAF bind to cardiac sarcomeres and play a role in regulating myofilament contractile activity.
Academic Article The single-strand DNA/RNA-binding protein, Purbeta, regulates serum response factor (SRF)-mediated cardiac muscle gene expression.
Academic Article SIRT3 is a stress-responsive deacetylase in cardiomyocytes that protects cells from stress-mediated cell death by deacetylation of Ku70.
Academic Article SIRT1 promotes cell survival under stress by deacetylation-dependent deactivation of poly(ADP-ribose) polymerase 1.
Academic Article HDAC3-dependent reversible lysine acetylation of cardiac myosin heavy chain isoforms modulates their enzymatic and motor activity.
Academic Article Pathogenic properties of the N-terminal region of cardiac myosin binding protein-C in vitro.
Academic Article Mitochondrial SIRT3 and heart disease.
Academic Article Activation of SIRT1, a class III histone deacetylase, contributes to fructose feeding-mediated induction of the alpha-myosin heavy chain expression.
Academic Article Emerging roles of SIRT1 deacetylase in regulating cardiomyocyte survival and hypertrophy.
Academic Article TEF-1 and MEF2 transcription factors interact to regulate muscle-specific promoters.
Academic Article Protein kinase-A dependent phosphorylation of transcription enhancer factor-1 represses its DNA-binding activity but enhances its gene activation ability.
Academic Article Physical interaction between the MADS box of serum response factor and the TEA/ATTS DNA-binding domain of transcription enhancer factor-1.
Academic Article Honokiol blocks and reverses cardiac hypertrophy in mice by activating mitochondrial Sirt3.
Academic Article Regulation of Akt signaling by sirtuins: its implication in cardiac hypertrophy and aging.
Academic Article Obesity-induced lysine acetylation increases cardiac fatty acid oxidation and impairs insulin signalling.
Academic Article Histone Deacetylase 3 (HDAC3)-dependent Reversible Lysine Acetylation of Cardiac Myosin Heavy Chain Isoforms Modulates Their Enzymatic and Motor Activity.
Academic Article SIRT3 Blocks Aging-Associated Tissue Fibrosis in Mice by Deacetylating and Activating Glycogen Synthase Kinase 3ß.
Academic Article The histone deacetylase SIRT6 blocks myostatin expression and development of muscle atrophy.
Grant Activation of sirtuins to prevent adverse cardiac remodeling after CABG
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  • Myocardium