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Gupta, Mahesh P.

One or more keywords matched the following items that are connected to Gupta, Mahesh P.

Item Type	Name
Concept	Myocardium
Academic Article	Increased expression of alternatively spliced dominant-negative isoform of SRF in human failing hearts.
Academic Article	Calcium/calmodulin-dependent protein kinase activates serum response factor transcription activity by its dissociation from histone deacetylase, HDAC4. Implications in cardiac muscle gene regulation during hypertrophy.
Academic Article	Poly(ADP-ribose) polymerase-1-deficient mice are protected from angiotensin II-induced cardiac hypertrophy.
Academic Article	Concurrent opposite effects of trichostatin A, an inhibitor of histone deacetylases, on expression of alpha-MHC and cardiac tubulins: implication for gain in cardiac muscle contractility.
Academic Article	HDAC4 and PCAF bind to cardiac sarcomeres and play a role in regulating myofilament contractile activity.
Academic Article	The single-strand DNA/RNA-binding protein, Purbeta, regulates serum response factor (SRF)-mediated cardiac muscle gene expression.
Academic Article	SIRT3 is a stress-responsive deacetylase in cardiomyocytes that protects cells from stress-mediated cell death by deacetylation of Ku70.
Academic Article	SIRT1 promotes cell survival under stress by deacetylation-dependent deactivation of poly(ADP-ribose) polymerase 1.
Academic Article	HDAC3-dependent reversible lysine acetylation of cardiac myosin heavy chain isoforms modulates their enzymatic and motor activity.
Academic Article	Pathogenic properties of the N-terminal region of cardiac myosin binding protein-C in vitro.
Academic Article	Mitochondrial SIRT3 and heart disease.
Academic Article	Activation of SIRT1, a class III histone deacetylase, contributes to fructose feeding-mediated induction of the alpha-myosin heavy chain expression.
Academic Article	Emerging roles of SIRT1 deacetylase in regulating cardiomyocyte survival and hypertrophy.
Academic Article	TEF-1 and MEF2 transcription factors interact to regulate muscle-specific promoters.
Academic Article	Protein kinase-A dependent phosphorylation of transcription enhancer factor-1 represses its DNA-binding activity but enhances its gene activation ability.
Academic Article	Physical interaction between the MADS box of serum response factor and the TEA/ATTS DNA-binding domain of transcription enhancer factor-1.
Academic Article	Honokiol blocks and reverses cardiac hypertrophy in mice by activating mitochondrial Sirt3.
Academic Article	Regulation of Akt signaling by sirtuins: its implication in cardiac hypertrophy and aging.
Academic Article	Obesity-induced lysine acetylation increases cardiac fatty acid oxidation and impairs insulin signalling.
Academic Article	Histone Deacetylase 3 (HDAC3)-dependent Reversible Lysine Acetylation of Cardiac Myosin Heavy Chain Isoforms Modulates Their Enzymatic and Motor Activity.
Academic Article	SIRT3 Blocks Aging-Associated Tissue Fibrosis in Mice by Deacetylating and Activating Glycogen Synthase Kinase 3ß.
Academic Article	The histone deacetylase SIRT6 blocks myostatin expression and development of muscle atrophy.
Grant	Activation of sirtuins to prevent adverse cardiac remodeling after CABG

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Myocardium