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Gupta, Mahesh P.
One or more keywords matched the following items that are connected to Gupta, Mahesh P.
Item TypeName
Concept Oxidative Stress
Academic Article Poly(ADP-ribose) polymerase-1-dependent cardiac myocyte cell death during heart failure is mediated by NAD+ depletion and reduced Sir2alpha deacetylase activity.
Academic Article Poly(ADP-ribose) polymerase-1-deficient mice are protected from angiotensin II-induced cardiac hypertrophy.
Academic Article Endothelial cell preservation at 10 degrees C minimizes catalytic iron, oxidative stress, and cold-induced injury.
Academic Article SIRT3 is a stress-responsive deacetylase in cardiomyocytes that protects cells from stress-mediated cell death by deacetylation of Ku70.
Academic Article Endothelial cell fatty acid unsaturation mediates cold-induced oxidative stress.
Academic Article Hypothermic preconditioning of endothelial cells attenuates cold-induced injury by a ferritin-dependent process.
Academic Article Sirt3 protects mitochondrial DNA damage and blocks the development of doxorubicin-induced cardiomyopathy in mice.
Academic Article SIRT2 regulates oxidative stress-induced cell death through deacetylation of c-Jun NH2-terminal kinase.
Academic Article Proteomic analysis of endothelial cold-adaptation.
Grant The Role of PARP-SIR2 Signaling in Heart Failure
Grant Blocking cardiac toxicity of anticancer drugs
Academic Article The nuclear and mitochondrial sirtuins, Sirt6 and Sirt3, regulate each other's activity and protect the heart from developing obesity-mediated diabetic cardiomyopathy.
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  • Oxidative Stress