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One or more keywords matched the following items that are connected to Polonsky, Kenneth S.
Item TypeName
Concept C-Peptide
Concept Peptide Fragments
Concept Glucagon-Like Peptide 1
Academic Article Defects in beta-cell function in functional ovarian hyperandrogenism.
Academic Article Alterations in the kinetics of C-peptide and insulin secretion in hyperthyroidism.
Academic Article Plasma insulin, C-peptide, and proinsulin concentrations in obese and nonobese individuals with varying degrees of glucose tolerance.
Academic Article Clinical phenotypes, insulin secretion, and insulin sensitivity in kindreds with maternally inherited diabetes and deafness due to mitochondrial tRNALeu(UUR) gene mutation.
Academic Article Analytical problems in detecting rapid insulin secretory pulses in normal humans.
Academic Article Oscillatory insulin secretion after pancreas transplant.
Academic Article Alterations in the ultradian oscillations of insulin secretion and plasma glucose in aging.
Academic Article Insulin acutely suppresses glucose production by both peripheral and hepatic effects in normal dogs.
Academic Article Basal and glucagon-stimulated plasma C-peptide concentrations in healthy dogs, dogs with diabetes mellitus, and dogs with hyperadrenocorticism.
Academic Article Altered insulin secretory responses to glucose in diabetic and nondiabetic subjects with mutations in the diabetes susceptibility gene MODY3 on chromosome 12.
Academic Article Evidence that insulin can directly inhibit hepatic glucose production.
Academic Article Late post-prandial hypoglycaemia as the sole presenting feature of secreting pancreatic beta-cell adenoma in a subtotally gastrectomized patient.
Academic Article Metabolic effects of troglitazone monotherapy in type 2 diabetes mellitus. A randomized, double-blind, placebo-controlled trial.
Academic Article Quantitative indexes of beta-cell function during graded up&down glucose infusion from C-peptide minimal models.
Academic Article GLP-1-induced alterations in the glucose-stimulated insulin secretory dose-response curve.
Academic Article Glucagon-like peptide 1 improves the ability of the beta-cell to sense and respond to glucose in subjects with impaired glucose tolerance.
Academic Article Failure of physiological plasma glucose excursions to entrain high-frequency pulsatile insulin secretion in type 2 diabetes.
Academic Article Abnormalities in the ultradian oscillations of insulin secretion and glucose levels in type 2 (non-insulin-dependent) diabetic patients.
Academic Article Glucagon-like peptide-1 stimulates insulin secretion by a Ca2+-independent mechanism in Zucker diabetic fatty rat islets of Langerhans.
Academic Article Estimation of insulin secretion rates from C-peptide levels. Comparison of individual and standard kinetic parameters for C-peptide clearance.
Academic Article Roles of insulin resistance and obesity in regulation of plasma insulin concentrations.
Academic Article Insulin release in impaired glucose tolerance: oral minimal model predicts normal sensitivity to glucose but defective response times.
Academic Article Insulin secretory responses to rising and falling glucose concentrations are delayed in subjects with impaired glucose tolerance.
Academic Article Oral glucose tolerance test minimal model indexes of beta-cell function and insulin sensitivity.
Academic Article C-peptide is the appropriate outcome measure for type 1 diabetes clinical trials to preserve beta-cell function: report of an ADA workshop, 21-22 October 2001.
Academic Article Persistence of oscillatory insulin secretion in denervated islet cell autografts.
Academic Article Entrainment of pulsatile insulin secretion by oscillatory glucose infusion.
Academic Article Fasting hypertriglyceridemia in noninsulin-dependent diabetes mellitus is an important predictor of postprandial lipid and lipoprotein abnormalities.
Academic Article Nocturnal elevation of glucose levels during fasting in noninsulin-dependent diabetes.
Academic Article Rosiglitazone reduces glucose-stimulated insulin secretion rate and increases insulin clearance in nondiabetic, insulin-resistant individuals.
Academic Article Effects of weight loss and reduced hyperglycemia on the kinetics of insulin secretion in obese non-insulin dependent diabetes mellitus.
Academic Article Hypoglycemia due to surreptitious injection of insulin. Identification of insulin species by high-performance liquid chromatography.
Academic Article International comparison of C-peptide measurements.
Academic Article Standardization of C-peptide measurements.
Academic Article Two-hour seven-sample oral glucose tolerance test and meal protocol: minimal model assessment of beta-cell responsivity and insulin sensitivity in nondiabetic individuals.
Academic Article Pattern of postprandial carbohydrate metabolism and effects of portal and peripheral insulin delivery.
Academic Article Weight loss therapy improves pancreatic endocrine function in obese older adults.
Academic Article Glyburide enhances the responsiveness of the beta-cell to glucose but does not correct the abnormal patterns of insulin secretion in noninsulin-dependent diabetes mellitus.
Academic Article TCF7L2 variant rs7903146 affects the risk of type 2 diabetes by modulating incretin action.
Academic Article Proinsulin radioimmunoassay in the evaluation of insulinomas and familial hyperproinsulinemia.
Academic Article Xenin-25 amplifies GIP-mediated insulin secretion in humans with normal and impaired glucose tolerance but not type 2 diabetes.
Academic Article In vivo pulsatility of pancreatic islet peptides.
Academic Article Quantitative study of insulin secretion and clearance in normal and obese subjects.
Academic Article Twenty-four-hour profiles and pulsatile patterns of insulin secretion in normal and obese subjects.
Academic Article The limitations to and valid use of C-peptide as a marker of the secretion of insulin.
Academic Article Insulin Wakayama: familial mutant insulin syndrome in Japan.
Academic Article Ingestion of a mixed meal does not affect the metabolic clearance rate of biosynthetic human C-peptide.
Academic Article Abnormal temporal patterns of glucose tolerance in obesity: relationship to sleep-related growth hormone secretion and circadian cortisol rhythmicity.
Academic Article Quantitative evaluation of the effect of low-intensity exercise on insulin secretion in man.
Academic Article Reevaluation of urine C-peptide as measure of insulin secretion.
Academic Article Abnormal patterns of insulin secretion in non-insulin-dependent diabetes mellitus.
Academic Article Effect of glyburide on beta cell responsiveness to glucose in non-insulin-dependent diabetes mellitus.
Academic Article The effects of biosynthetic human proinsulin on carbohydrate metabolism.
Academic Article Peripheral insulin parallels changes in insulin secretion more closely than C-peptide after bolus intravenous glucose administration.
Academic Article The measurement and validation of the nonsteady-state rates of C-peptide appearance in the dog.
Academic Article Pancreatic hormone profiles and metabolism posthepatectomy in the dog. Evidence for a hepatotrophic role of insulin, glucagon, and pancreatic polypeptide.
Academic Article Differential immunoreactivity of plasma glucagon components in man: studies with different glucagon antibodies.
Academic Article Alterations in the patterns of insulin secretion before and after diagnosis of IDDM.
Academic Article C-peptide and insulin secretion. Relationship between peripheral concentrations of C-peptide and insulin and their secretion rates in the dog.
Academic Article Calculated pattern of intraportal insulin appearance without independent assessment of C-peptide kinetics.
Academic Article Lack of effect of high-dose biosynthetic human C-peptide on pancreatic hormone release in normal subjects.
Academic Article Measurement of proinsulin and intermediates. Validation of immunoassay methods by high-performance liquid chromatography.
Academic Article Oscillations in insulin secretion during constant glucose infusion in normal man: relationship to changes in plasma glucose.
Academic Article Prior feeding alters the response to the 50-g glucose challenge test in pregnancy. The Staub-Traugott effect revisited.
Academic Article Insulin secretion in insulin-resistant women with a history of gestational diabetes.
Academic Article Xenin-25 potentiates glucose-dependent insulinotropic polypeptide action via a novel cholinergic relay mechanism.
Academic Article Insulin secretory profiles and C-peptide clearance kinetics at 6 months and 2 years after kidney-pancreas transplantation.
Academic Article Long-term follow-up of canine segmental pancreatic autografts.
Academic Article Natural history of intrahepatic canine islet cell autografts.
Academic Article Dose-dependent effects of oral and intravenous glucose on insulin secretion and clearance in normal humans.
Academic Article Metabolism of C-peptide in the dog. In vivo demonstration of the absence of hepatic extraction.
Academic Article Human insulin B24 (Phe----Ser). Secretion and metabolic clearance of the abnormal insulin in man and in a dog model.
Academic Article Familial hyperinsulinemia due to a structurally abnormal insulin. Definition of an emerging new clinical syndrome.
Academic Article A novel point mutation in the insulin gene giving rise to hyperproinsulinemia.
Academic Article Lilly Lecture 1994. The beta-cell in diabetes: from molecular genetics to clinical research.
Academic Article Alterations in immunoreactive proinsulin and insulin clearance induced by weight loss in NIDDM.
Academic Article Metabolic effects of short-term elevations of plasma cortisol are more pronounced in the evening than in the morning.
Academic Article International trial of the Edmonton protocol for islet transplantation.
Academic Article Effects of aging on insulin secretion.
Academic Article Lack of direct inhibition of insulin secretion by exogenous insulin in the canine pancreas.
Academic Article Reduction of insulin clearance during hyperglycemic clamp. Dose-response study in normal humans.
Academic Article Use of biosynthetic human C-peptide in the measurement of insulin secretion rates in normal volunteers and type I diabetic patients.
Academic Article Current approaches to measurement of insulin secretion.
Academic Article C-peptide as a measure of the secretion and hepatic extraction of insulin. Pitfalls and limitations.
Academic Article Lack of control by glucose of ultradian insulin secretory oscillations in impaired glucose tolerance and in non-insulin-dependent diabetes mellitus.
Academic Article Xenin-25 delays gastric emptying and reduces postprandial glucose levels in humans with and without type 2 diabetes.
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