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Perozo, Eduardo

One or more keywords matched the following items that are connected to Perozo, Eduardo

Item Type	Name
Concept	Ion Channels
Concept	Potassium Channels
Concept	Sodium Channels
Concept	Shaker Superfamily of Potassium Channels
Concept	Ether-A-Go-Go Potassium Channels
Concept	Potassium Channels, Inwardly Rectifying
Concept	Potassium Channels, Voltage-Gated
Concept	Potassium Channels, Calcium-Activated
Concept	Large-Conductance Calcium-Activated Potassium Channels
Academic Article	Voltage activation of reconstituted sodium channels: use of bacteriorhodopsin as a light-driven current source.
Academic Article	Structural dynamics of the Streptomyces lividans K+ channel (SKC1): secondary structure characterization from FTIR spectroscopy.
Academic Article	Three-dimensional architecture and gating mechanism of a K+ channel studied by EPR spectroscopy.
Academic Article	Structural dynamics of the Streptomyces lividans K+ channel (SKC1): oligomeric stoichiometry and stability.
Academic Article	Shedding light on voltage-dependent gating.
Academic Article	pH-dependent gating in the Streptomyces lividans K+ channel.
Academic Article	Gating currents in Shaker K+ channels. Implications for activation and inactivation models.
Academic Article	Molecular architecture of full-length KcsA: role of cytoplasmic domains in ion permeation and activation gating.
Academic Article	Structure of the KcsA channel intracellular gate in the open state.
Academic Article	Structure and packing orientation of transmembrane segments in voltage-dependent channels. Lessons from perturbation analysis.
Academic Article	Structural rearrangements underlying K+-channel activation gating.
Academic Article	Site-directed spin-labeling analysis of reconstituted Mscl in the closed state.
Academic Article	EPR approaches to ion channel structure and function.
Academic Article	Physical principles underlying the transduction of bilayer deformation forces during mechanosensitive channel gating.
Academic Article	Open channel structure of MscL and the gating mechanism of mechanosensitive channels.
Academic Article	New structural perspectives on K(+) channel gating.
Academic Article	Structural biology. Force and voltage sensors in one structure.
Academic Article	Structure and mechanism in prokaryotic mechanosensitive channels.
Academic Article	Single channel studies of the phosphorylation of K+ channels in the squid giant axon. I. Steady-state conditions.
Academic Article	Calculation of rigid-body conformational changes using restraint-driven Cartesian transformations.
Academic Article	Molecular basis of gating charge immobilization in Shaker potassium channels.
Academic Article	Electrostatic interaction of a K+ channel RCK domain with charged membrane surfaces.
Academic Article	Gating prokaryotic mechanosensitive channels.
Academic Article	Voltage-dependent gating at the KcsA selectivity filter.
Academic Article	An optimized purification and reconstitution method for the MscS channel: strategies for spectroscopical analysis.
Academic Article	Phosphorylation affects voltage gating of the delayed rectifier K+ channel by electrostatic interactions.
Academic Article	Phosphorylation of K+ channels in the squid giant axon. A mechanistic analysis.
Academic Article	How to gate an ion channel: lessons from MthK.
Academic Article	Single channel studies of the phosphorylation of K+ channels in the squid giant axon. II. Nonstationary conditions.
Academic Article	Structural biology: A channel with a twist.
Academic Article	A molecular mechanism for proton-dependent gating in KcsA.
Academic Article	Molecular determinants of gating at the potassium-channel selectivity filter.
Academic Article	Design and characterization of a constitutively open KcsA.
Academic Article	Structural basis for the coupling between activation and inactivation gates in K(+) channels.
Academic Article	Ion conduction through MscS as determined by electrophysiology and simulation.
Academic Article	On the structural basis of modal gating behavior in K(+) channels.
Academic Article	A quantitative description of KcsA gating I: macroscopic currents.
Academic Article	A quantitative description of KcsA gating II: single-channel currents.
Academic Article	Mechanism of activation gating in the full-length KcsA K+ channel.
Academic Article	Molecular coupling in the human ether-a-go-go-related gene-1 (hERG1) K+ channel inactivation pathway.
Academic Article	A designer ligand specific for Kv1.3 channels from a scorpion neurotoxin-based library.
Academic Article	Structural refinement of membrane proteins by restrained molecular dynamics and solvent accessibility data.
Academic Article	A structural mechanism for MscS gating in lipid bilayers.
Academic Article	Crystal structure of full-length KcsA in its closed conformation.
Academic Article	The activated state of a sodium channel voltage sensor in a membrane environment.
Academic Article	An emerging consensus on voltage-dependent gating from computational modeling and molecular dynamics simulations.
Academic Article	A multipoint hydrogen-bond network underlying KcsA C-type inactivation.
Academic Article	Modulation of K channels in dialyzed squid axons. ATP-mediated phosphorylation.
Academic Article	Thermodynamic coupling between activation and inactivation gating in potassium channels revealed by free energy molecular dynamics simulations.
Academic Article	Mechanism of Cd2+ coordination during slow inactivation in potassium channels.
Academic Article	Symmetry-constrained analysis of pulsed double electron-electron resonance (DEER) spectroscopy reveals the dynamic nature of the KcsA activation gate.
Academic Article	Gating of Shaker K+ channels: I. Ionic and gating currents.
Academic Article	S4 mutations alter gating currents of Shaker K channels.
Academic Article	Purification and reconstitution of functional Shaker K+ channels assayed with a light-driven voltage-control system.
Academic Article	Three-dimensional architecture of membrane-embedded MscS in the closed conformation.
Academic Article	Gating of Shaker K+ channels: II. The components of gating currents and a model of channel activation.
Academic Article	Reactions of cysteines substituted in the amphipathic N-terminal tail of a bacterial potassium channel with hydrophilic and hydrophobic maleimides.
Academic Article	The voltage sensor and the gate in ion channels.
Academic Article	Molecular architecture of the KvAP voltage-dependent K+ channel in a lipid bilayer.
Academic Article	Detection of the opening of the bundle crossing in KcsA with fluorescence lifetime spectroscopy reveals the existence of two gates for ion conduction.
Academic Article	Molecular driving forces determining potassium channel slow inactivation.
Academic Article	Structural dynamics of an isolated voltage-sensor domain in a lipid bilayer.
Academic Article	Structural mechanism of C-type inactivation in K(+) channels.
Academic Article	Chemical modification of squid axon K+ channel -SH groups with the organic mercurial compound p-hydroxymercuriphenylsulfonic acid (PHMPS).
Academic Article	Gating currents from a nonconducting mutant reveal open-closed conformations in Shaker K+ channels.
Academic Article	Recovery from slow inactivation in K+ channels is controlled by water molecules.
Academic Article	Importance of lipid-pore loop interface for potassium channel structure and function.
Academic Article	Structural basis of lipid-driven conformational transitions in the KvAP voltage-sensing domain.
Academic Article	Dynamics transitions at the outer vestibule of the KcsA potassium channel during gating.
Academic Article	Biochemical and structural analysis of the hyperpolarization-activated K(+) channel MVP.
Academic Article	Conformational dynamics at the inner gate of KcsA during activation.
Academic Article	Resting state of the human proton channel dimer in a lipid bilayer.
Academic Article	Multi-ion free energy landscapes underscore the microscopic mechanism of ion selectivity in the KcsA channel.
Academic Article	The role of MscL amphipathic N terminus indicates a blueprint for bilayer-mediated gating of mechanosensitive channels.
Academic Article	Instantaneous ion configurations in the K+ ion channel selectivity filter revealed by 2D IR spectroscopy.
Academic Article	Toward a structural blueprint for bilayer-mediated channel mechanosensitivity.
Academic Article	Probing the Effects of Gating on the Ion Occupancy of the K+ Channel Selectivity Filter Using Two-Dimensional Infrared Spectroscopy.
Academic Article	Chemical substitutions in the selectivity filter of potassium channels do not rule out constricted-like conformations for C-type inactivation.
Academic Article	Towards a Structural View of Drug Binding to hERG K+ Channels.
Academic Article	Role of human Hv1 channels in sperm capacitation and white blood cell respiratory burst established by a designed peptide inhibitor.
Academic Article	Never at rest: insights into the conformational dynamics of ion channels from cryo-electron microscopy.
Academic Article	Rapid constriction of the selectivity filter underlies C-type inactivation in the KcsA potassium channel.
Academic Article	Structural Dynamics of the MscL C-terminal Domain.
Academic Article	Molecular basis of force-from-lipids gating in the mechanosensitive channel MscS.
Academic Article	Electromechanical coupling in the hyperpolarization-activated K+ channel KAT1.
Academic Article	Direct activation of the proton channel by albumin leads to human sperm capacitation and sustained release of inflammatory mediators by neutrophils.
Academic Article	Computational study of non-conductive selectivity filter conformations and C-type inactivation in a voltage-dependent potassium channel.
Academic Article	Molecular determinants of inhibition of the human proton channel hHv1 by the designer peptide C6 and a bivalent derivative.
Academic Article	Mechanism of voltage sensing in Ca2+- and voltage-activated K+ (BK) channels.
Academic Article	State-specific morphological deformations of the lipid bilayer explain mechanosensitive gating of MscS ion channels.
Concept	Voltage-Gated Sodium Channels
Grant	Midwest Center for Membrane Protein Structural Dynamics
Grant	MOLECULAR ARCHITECTURE OF POTASSIUM CHANNELS
Grant	High Resolution Structural Dynamics of K Channels
Grant	Structural Basis of “Force from Lipids” Activation in Mechanosensitive Channels
Grant	Structural Dynamics of Mechanosensitive Channels
Grant	Structural basis for transmembrane Mg2+ transport
Academic Article	Conformation-specific Synthetic Antibodies Discriminate Multiple Functional States of the Ion Channel CorA.
Grant	Structural Basis of Coupling and Dynamics in K+ Channels
Academic Article	Potassium dependent structural changes in the selectivity filter of HERG potassium channels.

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Hyperpolarization Activated Cyclic Nucleotide Gated Channels