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Weichselbaum, Ralph R.
One or more keywords matched the following items that are connected to Weichselbaum, Ralph R.
Item TypeName
Concept DNA Damage
Concept DNA Nucleotidyltransferases
Concept DNA-Binding Proteins
Concept DNA, Mitochondrial
Concept DNA Repair
Concept DNA Mutational Analysis
Concept DNA, Neoplasm
Concept DNA
Concept DNA Topoisomerases, Type II
Concept DNA-Directed DNA Polymerase
Concept DNA (Cytosine-5-)-Methyltransferases
Concept DNA Replication
Concept DNA, Viral
Concept DNA Probes
Concept DNA, Complementary
Concept DNA-Activated Protein Kinase
Concept DNA Repair Enzymes
Concept Vaccines, DNA
Concept DNA Breaks, Double-Stranded
Concept DNA Copy Number Variations
Concept DNA Methylation
Concept O(6)-Methylguanine-DNA Methyltransferase
Concept DNA Restriction Enzymes
Concept DNA Helicases
Concept DNA, Single-Stranded
Concept DNA Primers
Academic Article Reactive oxygen intermediates target CC(A/T)6GG sequences to mediate activation of the early growth response 1 transcription factor gene by ionizing radiation.
Academic Article C-jun and Egr-1 participate in DNA synthesis and cell survival in response to ionizing radiation exposure.
Academic Article Radiation signaling mediated by Jun activation following dissociation from a cell type-specific repressor.
Academic Article Coinduction of c-jun gene expression and internucleosomal DNA fragmentation by ionizing radiation.
Academic Article The stress response to ionizing radiation involoves c-Abl-dependent phosphorylation of SHPTP1.
Academic Article Role for c-Abl tyrosine kinase in growth arrest response to DNA damage.
Academic Article Role for Bcl-xL as an inhibitor of cytosolic cytochrome C accumulation in DNA damage-induced apoptosis.
Academic Article Proteolytic activation of protein kinase C delta by an ICE-like protease in apoptotic cells.
Academic Article DNA double-strand break rejoining rates, inherent radiation sensitivity and human tumour response to radiotherapy.
Academic Article Nuclear signaling induced by ionizing radiation involves colocalization of the activated p56/p53lyn tyrosine kinase with p34cdc2.
Academic Article Enhancement of replication of genetically engineered herpes simplex viruses by ionizing radiation: a new paradigm for destruction of therapeutically intractable tumors.
Academic Article Inhibition of protein kinases sensitizes human tumor cells to ionizing radiation.
Academic Article Increased injection number enhances adenoviral genetic radiotherapy.
Academic Article Functional interaction between DNA-PK and c-Abl in response to DNA damage.
Academic Article The contribution of DNA ploidy to radiation sensitivity in human tumour cell lines.
Academic Article Role for caspase-mediated cleavage of Rad51 in induction of apoptosis by DNA damage.
Academic Article Regulation of Rad51 function by c-Abl in response to DNA damage.
Academic Article The essential functions of human Rad51 are independent of ATP hydrolysis.
Academic Article Determination of cell fate by c-Abl activation in the response to DNA damage.
Academic Article p73 is regulated by tyrosine kinase c-Abl in the apoptotic response to DNA damage.
Academic Article Expression of the polymorphic human DNA repair gene XRCC1 does not correlate with radiosensitivity in the cells of human head and neck tumor cell lines.
Academic Article Accumulation of specific RNAs encoding transcriptional factors and stress response proteins against a background of severe depletion of cellular RNAs in cells infected with herpes simplex virus 1.
Academic Article Role for Lyn tyrosine kinase as a regulator of stress-activated protein kinase activity in response to DNA damage.
Academic Article Regulation of DNA-dependent protein kinase by the Lyn tyrosine kinase.
Academic Article Role for p300 in stabilization of p53 in the response to DNA damage.
Academic Article Radiation-inducible gene therapy.
Academic Article Adenoviral TNF-alpha gene therapy and radiation damage tumor vasculature in a human malignant glioma xenograft.
Academic Article Xrcc3 is required for assembly of Rad51 complexes in vivo.
Academic Article Molecular targeting of gene therapy and radiotherapy.
Academic Article Translocation of SAPK/JNK to mitochondria and interaction with Bcl-x(L) in response to DNA damage.
Academic Article Function for p300 and not CBP in the apoptotic response to DNA damage.
Academic Article Activation of MEK kinase 1 by the c-Abl protein tyrosine kinase in response to DNA damage.
Academic Article E2F proteins are posttranslationally modified concomitantly with a reduction in nuclear binding activity in cells infected with herpes simplex virus 1.
Academic Article Quantitative analysis of DNA array autoradiographs.
Academic Article cis-Diamminedichloroplatinum(II) induces c-jun expression in human myeloid leukemia cells: potential involvement of a protein kinase C-dependent signaling pathway.
Academic Article Combined gene therapy and ionizing radiation is a novel approach to treat human esophageal adenocarcinoma.
Academic Article Radiation-induced DNA double-strand break frequencies in human squamous cell carcinoma cell lines of different radiation sensitivities.
Academic Article cdc2 cyclin-dependent kinase binds and phosphorylates herpes simplex virus 1 U(L)42 DNA synthesis processivity factor.
Academic Article Dose-dependent and independent temporal patterns of gene responses to ionizing radiation in normal and tumor cells and tumor xenografts.
Academic Article The breast cancer susceptibility gene BRCA1 is required for subnuclear assembly of Rad51 and survival following treatment with the DNA cross-linking agent cisplatin.
Academic Article Evidence for the expression of radiation-induced potentially lethal damage being a p53-dependent process.
Academic Article Herpes simplex virus 1 activates cdc2 to recruit topoisomerase II alpha for post-DNA synthesis expression of late genes.
Academic Article Ionizing radiation induces expression and binding activity of the nuclear factor kappa B.
Academic Article Transcriptional control of viral gene therapy by cisplatin.
Academic Article Protein kinase C mediates x-ray inducibility of nuclear signal transducers EGR1 and JUN.
Academic Article Control of gene therapy by MDR1 and EGR1 promoter sequences in transcriptional targeting by chemotherapy (Review).
Academic Article STAT1 is overexpressed in tumors selected for radioresistance and confers protection from radiation in transduced sensitive cells.
Academic Article Radiation-induced tumour necrosis factor-alpha expression: clinical application of transcriptional and physical targeting of gene therapy.
Academic Article Radiation therapy: activation for gene transcription and the development of genetic radiotherapy-therapeutic strategies in oncology.
Academic Article Dual induction of the Epo-Egr-TNF-alpha- plasmid in hypoxic human colon adenocarcinoma produces tumor growth delay.
Academic Article Two prostate carcinoma cell lines demonstrate abnormalities in tumor suppressor genes.
Academic Article Progression of Barrett's metaplasia to adenocarcinoma is associated with the suppression of the transcriptional programs of epidermal differentiation.
Academic Article Cellular and molecular aspects of human tumor radioresistance.
Academic Article Radiation's outer limits.
Academic Article Receiver operating characteristic analysis: a general tool for DNA array data filtration and performance estimation.
Academic Article Chemoinducible gene therapy: a strategy to enhance doxorubicin antitumor activity.
Academic Article Ionizing radiation activates late herpes simplex virus 1 promoters via the p38 pathway in tumors treated with oncolytic viruses.
Academic Article Adenovirally delivered tumor necrosis factor-alpha improves the antiglioma efficacy of concomitant radiation and temozolomide therapy.
Academic Article Ionizing radiation regulates expression of the c-jun protooncogene.
Academic Article A hot spot for RAD51C interactions revealed by a peptide that sensitizes cells to cisplatin.
Academic Article Relevance and irrelevance of DNA damage response to radiotherapy.
Academic Article An interferon-related gene signature for DNA damage resistance is a predictive marker for chemotherapy and radiation for breast cancer.
Academic Article Prediction of the radiation sensitivity of human squamous cell carcinoma cells using DNA filter elution.
Academic Article c-Abl tyrosine kinase regulates caspase-9 autocleavage in the apoptotic response to DNA damage.
Academic Article Response of human osteosarcoma in vitro to irradiation: evidence for unusual cellular repair activity.
Academic Article Chromosomal sensitivity of lymphocytes from individuals with therapy-related acute nonlymphocytic leukemia.
Academic Article Defective reactivation of ultraviolet light-irradiated herpesvirus by a Bloom's syndrome fibroblast strain.
Academic Article Chemo-inducible gene therapy.
Academic Article Pilot study examining tumor expression of RAD51 and clinical outcomes in human head cancers.
Academic Article Radioresistance of Stat1 over-expressing tumour cells is associated with suppressed apoptotic response to cytotoxic agents and increased IL6-IL8 signalling.
Academic Article Response of human prostate cancer cells and tumors to combining PARP inhibition with ionizing radiation.
Academic Article Southern analysis of human head and neck cancer cells for homologous sequences using yeast gamma repair genes.
Academic Article Molecular pathways: interferon/stat1 pathway: role in the tumor resistance to genotoxic stress and aggressive growth.
Academic Article A chemical compound that stimulates the human homologous recombination protein RAD51.
Academic Article Faster repair of DNA double-strand breaks in radioresistant human tumor cells.
Academic Article Heterogeneous response to X-ray and ultraviolet light irradiations of cultured skin fibroblasts in two families with Gardner's Syndrome.
Academic Article Inherent cellular radiosensitivity of human tumors of varying clinical curability.
Academic Article Synergistic cytotoxicity and DNA strand break formation by bromodeoxyuridine and bleomycin in human tumor cells.
Academic Article Chromosome 13 homozygosity in osteosarcoma without retinoblastoma.
Academic Article Radiation-resistant and repair-proficient human tumor cells may be associated with radiotherapy failure in head- and neck-cancer patients.
Academic Article The maximum recovery potential of human tumor cells may predict clinical outcome in radiotherapy.
Academic Article Lethal effects of 1-beta-D-arabinofuranosylcytosine incorporation into deoxyribonucleic acid during ultraviolet repair.
Academic Article Spleen cells from young but not old immunized mice eradicate large established cancers.
Academic Article Repair of potentially lethal X-ray damage in fibroblasts derived from patients with hereditary and D-deletion retinoblastoma.
Academic Article Comutagenic effects of 3-aminobenzamide in Chinese hamster ovary cells.
Academic Article Some retinoblastomas, osteosarcomas, and soft tissue sarcomas may share a common etiology.
Academic Article Comparative analysis of the inherent radiosensitivity of ovarian carcinoma.
Academic Article Efficacy of the multi-kinase inhibitor enzastaurin is dependent on cellular signaling context.
Academic Article Overexpression of Bcl-XL by cytotoxic drug exposure confers resistance to ionizing radiation-induced internucleosomal DNA fragmentation.
Academic Article Occurrence of p53 gene deletions and human papilloma virus infection in human head and neck cancer.
Academic Article Effect of Bcl-2 on ionizing radiation and 1-beta-D-arabinofuranosylcytosine-induced internucleosomal DNA fragmentation and cell survival in human myeloid leukemia cells.
Academic Article Radioresistant and repair proficient cells may determine radiocurability in human tumors.
Academic Article Recovery from sublethal and potentially lethal damage in an X-ray-sensitive CHO cell.
Academic Article Deficient recovery from potentially lethal radiation damage in ataxia telengiectasia and xeroderma pigmentosum.
Academic Article Antipain-mediated suppression of sister chromatid exchanges induced by an inhibitor of poly (ADP-ribose) polymerase.
Academic Article Different efficiencies of interaction between 3-aminobenzamide and various monofunctional alkylating agents in the induction of sister chromatid exchanges.
Academic Article The role of DNA repair processes in the response of human tumors to fractionated radiotherapy.
Academic Article An in vitro investigation of x-ray sensitivity in fibroblasts from patients with retinoblastoma.
Academic Article Activation of the c-Abl tyrosine kinase in the stress response to DNA-damaging agents.
Academic Article The raf oncogene is associated with a radiation-resistant human laryngeal cancer.
Academic Article Gene therapy targeted by radiation preferentially radiosensitizes tumor cells.
Academic Article Ionizing radiation activates transcription of the EGR1 gene via CArG elements.
Academic Article Potentially lethal damage repair (PLDR) in X-irradiated cultures of a normal human diploid fibroblast cell strain.
Academic Article Radioresistance in some human tumor cells conferred in vitro by repair of potentially lethal X-ray damage.
Academic Article Familial retinoblastoma and ataxia telangiectasia: human models for the study of DNA damage and repair.
Academic Article Spatial and temporal control of gene therapy using ionizing radiation.
Academic Article Cellular and molecular mechanisms of radioresistance.
Academic Article Ketoconazole attenuates radiation-induction of tumor necrosis factor.
Academic Article DNA repair in a Fanconi's anemia fibroblast cell strain.
Academic Article Investigation of the cytotoxic effects of DNA damaging agents on neurofibromatosis cells.
Academic Article Chromosome 13 restriction fragment length polymorphisms.
Academic Article Activation of p38 mitogen-activated protein kinase by c-Abl-dependent and -independent mechanisms.
Academic Article Abnormal sensitivity of diploid skin fibroblasts from a family with gardner's syndrome to the lethal effects of X-irradiation, ultraviolet light and mitomycin-C.
Academic Article Blockage of the early events of mitogenic signaling by interferon-gamma in macrophages in response to colony-stimulating factor-1.
Academic Article Regulation of DNA damage-induced apoptosis by the c-Abl tyrosine kinase.
Academic Article New findings in the chromosome 13 long-arm deletion syndrome and retinoblastoma.
Academic Article Functional role for the c-Abl protein tyrosine kinase in the cellular response to genotoxic stress.
Academic Article Suppression of Bcl-2 messenger RNA production may mediate apoptosis after ionizing radiation, tumor necrosis factor alpha, and ceramide.
Academic Article Molecular targets to overcome radioresistance.
Academic Article Inactivation of DNA-dependent protein kinase by protein kinase Cdelta: implications for apoptosis.
Academic Article The disappearance of cyclins A and B and the increase in activity of the G(2)/M-phase cellular kinase cdc2 in herpes simplex virus 1-infected cells require expression of the alpha22/U(S)1.5 and U(L)13 viral genes.
Academic Article Measurement of bioreduction rates of cells with distinct responses to ionizing radiation and cisplatin.
Academic Article Assembly of RecA-like recombinases: distinct roles for mediator proteins in mitosis and meiosis.
Academic Article Radioresistant derivatives of an X-ray-sensitive CHO cell line exhibit distinct patterns of sensitivity to DNA-damaging agents.
Academic Article Method of RNA purification from endothelial cells for DNA array experiments.
Academic Article Frequent 3p allele loss and epigenetic inactivation of the RASSF1A tumour suppressor gene from region 3p21.3 in head and neck squamous cell carcinoma.
Academic Article Oct-1 is posttranslationally modified and exhibits reduced capacity to bind cognate sites at late times after infection with herpes simplex virus 1.
Academic Article Glioblastoma cells block radiation-induced programmed cell death of endothelial cells.
Academic Article gamma-H2AX as a therapeutic target for improving the efficacy of radiation therapy.
Academic Article Inhibition of nuclear factor-kappaB activity by temozolomide involves O6-methylguanine induced inhibition of p65 DNA binding.
Academic Article X-ray sensitivity of diploid fibroblasts from patients with hereditary or sporadic retinoblastoma.
Academic Article p50 (NF-?B1) is an effector protein in the cytotoxic response to DNA methylation damage.
Academic Article Expression and methylation of the Blym gene in human tumor cell lines.
Academic Article The repair of potentially lethal damage in x-irradiated cultures of normal and ataxia telangiectasia human fibroblasts.
Academic Article p53 mutation does not correlate with radiosensitivity in 24 head and neck cancer cell lines.
Academic Article DNA damage-induced cytotoxicity is mediated by the cooperative interaction of phospho-NF-?B p50 and a single nucleotide in the ?B-site.
Academic Article A phase I dose escalation study of Ad GV.EGR.TNF.11D (TNFerade™ Biologic) with concurrent chemoradiotherapy in patients with recurrent head and neck cancer undergoing reirradiation.
Academic Article Integrative and comparative genomic analysis of HPV-positive and HPV-negative head and neck squamous cell carcinomas.
Academic Article Nfkb1 is a haploinsufficient DNA damage-specific tumor suppressor.
Academic Article DNA repair biomarkers XPF and phospho-MAPKAP kinase 2 correlate with clinical outcome in advanced head and neck cancer.
Academic Article Poly (ADP-ribose) polymerase inhibitor efficacy in head and neck cancer.
Academic Article Loss of Nfkb1 leads to early onset aging.
Academic Article STING-Dependent Cytosolic DNA Sensing Promotes Radiation-Induced Type I Interferon-Dependent Antitumor Immunity in Immunogenic Tumors.
Academic Article S-phase-dependent p50/NF-?B1 phosphorylation in response to ATR and replication stress acts to maintain genomic stability.
Academic Article RAD54 family translocases counter genotoxic effects of RAD51 in human tumor cells.
Academic Article Radiation as an immune modulator.
Academic Article The RAD51-stimulatory compound RS-1 can exploit the RAD51 overexpression that exists in cancer cells and tumors.
Academic Article DNA repair pathway gene expression score correlates with repair proficiency and tumor sensitivity to chemotherapy.
Academic Article From DNA Damage to Nucleic Acid Sensing: A Strategy to Enhance Radiation Therapy.
Academic Article Linking Cancer Metabolism to DNA Repair and Accelerated Senescence.
Academic Article Repurposing cephalosporin antibiotics as pro-senescent radiosensitizers.
Academic Article MUC1-C Oncoprotein Interacts Directly with ATM and Promotes the DNA Damage Response to Ionizing Radiation.
Academic Article Expression and mutational analysis of c-CBL and its relationship to the MET receptor in head and neck squamous cell carcinoma.
Academic Article Low Recombination Proficiency Score (RPS) Predicts Heightened Sensitivity to DNA-Damaging Chemotherapy in Breast Cancer.
Academic Article Systemic delivery of the tumor necrosis factor gene to tumors by a novel dual DNA-nanocomplex in a nanoparticle system.
Academic Article Dendritic Cells but Not Macrophages Sense Tumor Mitochondrial DNA for Cross-priming through Signal Regulatory Protein a Signaling.
Academic Article HMG-CoA Reductase Inhibition Delays DNA Repair and Promotes Senescence After Tumor Irradiation.
Academic Article Non-canonical NF-?B Antagonizes STING Sensor-Mediated DNA Sensing in Radiotherapy.
Academic Article DNA Methylation Controls Metastasis-Suppressive 14q32-Encoded miRNAs.
Academic Article Temozolomide Treatment Induces lncRNA MALAT1 in an NF-?B and p53 Codependent Manner in Glioblastoma.
Academic Article A Phase 1 Trial Assessing the Safety and Tolerability of a Therapeutic DNA Vaccination Against HPV16 and HPV18 E6/E7 Oncogenes After Chemoradiation for Cervical Cancer.
Academic Article DDX39B interacts with the pattern recognition receptor pathway to inhibit NF-?B and sensitize to alkylating chemotherapy.
Academic Article The AIM2 and NLRP3 inflammasomes trigger IL-1-mediated antitumor effects during radiation.
Academic Article Loss of MEN1 function impairs DNA repair capability of pancreatic neuroendocrine tumors.
Concept DNA (Cytosine-5-)-Methyltransferase 1
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