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Wainwright, Derek

One or more keywords matched the following items that are connected to Wainwright, Derek

Item Type	Name
Concept	Glioblastoma
Academic Article	Characterization and immunotherapeutic implications for a novel antibody targeting interleukin (IL)-13 receptor a2.
Academic Article	IDO expression in brain tumors increases the recruitment of regulatory T cells and negatively impacts survival.
Academic Article	Thymus-derived rather than tumor-induced regulatory T cells predominate in brain tumors.
Academic Article	Nanoparticle-programmed self-destructive neural stem cells for glioblastoma targeting and therapy.
Academic Article	Fibrin-binding, peptide amphiphile micelles for targeting glioblastoma.
Academic Article	The kynurenine to tryptophan ratio as a prognostic tool for glioblastoma patients enrolling in immunotherapy.
Academic Article	Advanced age negatively impacts survival in an experimental brain tumor model.
Academic Article	The Kynurenine/Tryptophan Ratio and Glioblastoma Patients Treated with Hsppc-96 Vaccine.
Academic Article	Non-tumor cell IDO1 predominantly contributes to enzyme activity and response to CTLA-4/PD-L1 inhibition in mouse glioblastoma.
Academic Article	Lessons learned from rindopepimut treatment in patients with EGFRvIII-expressing glioblastoma.
Academic Article	IDO1 Inhibition Synergizes with Radiation and PD-1 Blockade to Durably Increase Survival Against Advanced Glioblastoma.
Academic Article	Imaging tryptophan uptake with positron emission tomography in glioblastoma patients treated with indoximod.
Academic Article	Infiltrating T Cells Increase IDO1 Expression in Glioblastoma and Contribute to Decreased Patient Survival.
Academic Article	Management of glioblastoma in elderly patients.
Academic Article	Commentary: preclinical efficacy of immune-checkpoint monotherapy does not recapitulate corresponding biomarkers-based clinical predictions in glioblastoma by Garg et al. (2017).
Academic Article	Newly Diagnosed Glioblastoma: A Review on Clinical Management.
Academic Article	The Coincidence Between Increasing Age, Immunosuppression, and the Incidence of Patients With Glioblastoma.
Academic Article	A retrospective survival analysis of Glioblastoma patients treated with selective serotonin reuptake inhibitors.
Academic Article	Advanced Age Increases Immunosuppression in the Brain and Decreases Immunotherapeutic Efficacy in Subjects with Glioblastoma.
Academic Article	Immunosuppressive IDO in Cancer: Mechanisms of Action, Animal Models, and Targeting Strategies.
Academic Article	Unique challenges for glioblastoma immunotherapy-discussions across neuro-oncology and non-neuro-oncology experts in cancer immunology. Meeting Report from the 2019 SNO Immuno-Oncology Think Tank.
Academic Article	Tumor Cell IDO Enhances Immune Suppression and Decreases Survival Independent of Tryptophan Metabolism in Glioblastoma.
Academic Article	Glioblastoma as an age-related neurological disorder in adults.
Academic Article	Targeting glioblastoma signaling and metabolism with a re-purposed brain-penetrant drug.
Academic Article	Circadian Regulator CLOCK Drives Immunosuppression in Glioblastoma.
Academic Article	Next Steps for Immunotherapy in Glioblastoma.
Academic Article	Identification and Characterization of a Novel Indoleamine 2,3-Dioxygenase 1 Protein Degrader for Glioblastoma.
Grant	The role of IDO and Th17 in an experimental mouse model of glioma
Grant	The interaction of IDO and Tregs Leads to Immunosuppression in Glioma
Grant	The interaction of IDO and Tregs Leads to Immunosuppression in Glioma
Grant	Aging, immunosenescence and glioblastoma
Grant	IDO1 and Immunotolerance in Glioblastoma
Academic Article	Advanced Age in Humans and Mouse Models of Glioblastoma Show Decreased Survival from Extratumoral Influence.
Grant	Extratumoral biological determinants that decrease survival in older adults with glioblastoma
Academic Article	Lactate dehydrogenase A regulates tumor-macrophage symbiosis to promote glioblastoma progression.
Academic Article	LDHA-regulated tumor-macrophage symbiosis promotes glioblastoma progression.
Academic Article	Age-stratified comorbid and pharmacologic analysis of patients with glioblastoma.

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Glioblastoma