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Wainwright, Derek
One or more keywords matched the following properties of Wainwright, Derek
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Person ID 253
One or more keywords matched the following items that are connected to Wainwright, Derek
Item TypeName
Concept Adenoviridae
Concept Age Factors
Concept Amyotrophic Lateral Sclerosis
Concept Antibiotics, Antineoplastic
Concept Antibodies, Neoplasm
Concept Antigen-Presenting Cells
Concept Autophagy
Concept Bone Marrow Cells
Concept Aging
Concept Adrenergic beta-Antagonists
Concept Budgets
Concept Antineoplastic Agents
Concept Carcinoma, Squamous Cell
Concept Antineoplastic Combined Chemotherapy Protocols
Concept Analysis of Variance
Concept Antibodies, Monoclonal
Concept Antigens, Differentiation, T-Lymphocyte
Concept Base Sequence
Concept Cell Count
Concept DNA Damage
Concept Burns
Concept Basement Membrane
Concept Astrocytoma
Concept Attitude of Health Personnel
Concept England
Concept Carcinoma, Non-Small-Cell Lung
Concept Cell Division
Concept Carbocyanines
Concept Clone Cells
Concept Fibrin
Concept Blood-Brain Barrier
Concept Genetic Vectors
Concept Cricetulus
Concept Confidentiality
Concept Contrast Media
Concept Dementia
Concept Hospital Bed Capacity, 300 to 499
Concept Dacarbazine
Concept Immune System
Concept Dendritic Cells
Concept Drug Carriers
Concept Facial Nerve
Concept Flagellin
Concept Graft Survival
Concept Hospitals, Public
Concept Hybridomas
Concept Enzyme Inhibitors
Concept Drosophila melanogaster
Concept Drug Evaluation, Preclinical
Concept Drug Therapy, Combination
Concept Fluoxetine
Concept Facial Nerve Diseases
Concept Fibroblasts
Concept Metalloporphyrins
Concept Enzyme Activation
Concept Glioma
Concept Glial Fibrillary Acidic Protein
Concept Glioblastoma
Concept Feasibility Studies
Concept Fibronectins
Concept Financial Management
Concept Killer Cells, Natural
Concept Gold
Concept T-Lymphocytes, Helper-Inducer
Concept Hydrogen-Ion Concentration
Concept Energy Metabolism
Concept Enzyme-Linked Immunosorbent Assay
Concept Hospital Information Systems
Concept Flow Cytometry
Concept Fluorescent Antibody Technique
Concept Macrophages
Concept Membrane Glycoproteins
Concept Hospital Bed Capacity, 500 and over
Concept Pilot Projects
Concept Mice, Transgenic
Concept Extracellular Matrix
Concept Molecular Sequence Data
Concept Mice, Inbred BALB C
Concept Mice, Inbred C57BL
Concept Mice, Nude
Concept Micelles
Concept Mutation
Concept Cricetinae
Concept HeLa Cells
Concept Ovalbumin
Concept Oxidation-Reduction
Concept Lung Neoplasms
Concept Sphingomyelin Phosphodiesterase
Concept Immunoenzyme Techniques
Concept Repressor Proteins
Concept Interferon-gamma
Concept Interprofessional Relations
Concept Cohort Studies
Concept Regulatory Sequences, Nucleic Acid
Concept Salmonella typhimurium
Concept State Medicine
Concept Humans
Concept Sphingomyelins
Concept Transcription, Genetic
Concept Synapses
Concept Specific Pathogen-Free Organisms
Concept CHO Cells
Concept Practice Guidelines as Topic
Concept Vaccination
Concept Histocompatibility Antigens Class I
Concept Lysosomes
Concept Transduction, Genetic
Concept Th1 Cells
Concept Randomized Controlled Trials as Topic
Concept Risk Assessment
Concept Reverse Transcriptase Polymerase Chain Reaction
Concept Tumor Cells, Cultured
Concept Central Nervous System Neoplasms
Concept Up-Regulation
Concept Antigens, Differentiation, Myelomonocytic
Concept Antigens, CD
Concept Lymph Nodes
Concept CD4-Positive T-Lymphocytes
Concept Cysteine Proteinase Inhibitors
Concept Immunotherapy, Adoptive
Concept Lymphocytes, Tumor-Infiltrating
Concept Interleukin-10
Concept Gene Expression
Concept Mutagenesis, Site-Directed
Concept Drug Delivery Systems
Concept T-Lymphocyte Subsets
Concept Sigmodontinae
Concept Meningeal Neoplasms
Concept Morphogenesis
Concept Treatment Outcome
Concept Interferon-alpha
Concept Sequence Deletion
Concept Mice, Knockout
Concept CD8-Positive T-Lymphocytes
Concept Gene Expression Regulation, Developmental
Concept Cell Proliferation
Concept Chemokines
Concept Disease Progression
Concept Interleukin-12
Concept Inhibitor of Apoptosis Proteins
Concept Th2 Cells
Concept Axotomy
Concept Integrin beta1
Concept Brain-Derived Neurotrophic Factor
Concept Cancer Vaccines
Concept Jurkat Cells
Concept B7-H1 Antigen
Concept Positron-Emission Tomography
Concept Indoleamine-Pyrrole 2,3,-Dioxygenase
Concept Neovascularization, Physiologic
Concept Oligonucleotide Array Sequence Analysis
Concept Adoptive Transfer
Concept Lactic Acid
Concept Facial Nerve Injuries
Concept Gene Expression Profiling
Concept STAT3 Transcription Factor
Concept Mice
Concept Surveys and Questionnaires
Concept Severity of Illness Index
Concept CD11c Antigen
Concept Upper Extremity
Concept HEK293 Cells
Concept Molecular Targeted Therapy
Concept Rats
Concept ARNTL Transcription Factors
Concept Cognitive Dysfunction
Concept Real-Time Polymerase Chain Reaction
Concept CTLA-4 Antigen
Concept Sex Factors
Concept Interleukin-2 Receptor alpha Subunit
Concept Spleen
Concept Blotting, Western
Concept Toll-Like Receptor 2
Concept Survival Analysis
Concept Electronic Health Records
Concept Transfection
Concept Tuberous Sclerosis
Concept Patient Satisfaction
Concept Genetic Therapy
Concept Cell Hypoxia
Concept Minor Histocompatibility Antigens
Concept Survival Rate
Concept Skin Transplantation
Concept Polymerase Chain Reaction
Concept G2 Phase
Concept Chemokine CCL2
Concept DNA Methylation
Concept Glucocorticoid-Induced TNFR-Related Protein
Concept Interleukin-13 Receptor alpha2 Subunit
Concept Interleukin-17
Concept Gene Silencing
Concept Xenograft Model Antitumor Assays
Concept Gene Knockdown Techniques
Concept Cell Lineage
Concept Health Care Surveys
Concept T-Lymphocytes, Regulatory
Concept gp100 Melanoma Antigen
Concept Basic Helix-Loop-Helix Transcription Factors
Concept CLOCK Proteins
Concept Immune Evasion
Concept Antibodies, Monoclonal, Murine-Derived
Concept Tumor Microenvironment
Concept Lectins, C-Type
Concept Programmed Cell Death 1 Receptor
Concept Receptor, Adenosine A2A
Concept Cell Line, Tumor
Concept Kaplan-Meier Estimate
Concept Chemokine CCL11
Concept Drug Repositioning
Concept Neuroimaging
Concept Brain Neoplasms
Concept Cell Survival
Concept Cells, Cultured
Concept Clinical Trials as Topic
Concept Cloning, Molecular
Concept Coronary Vessels
Concept Disease Models, Animal
Concept Doxorubicin
Concept Family Practice
Concept Follow-Up Studies
Concept Kynurenic Acid
Concept Longitudinal Studies
Concept Lymphocyte Activation
Concept Magnetic Resonance Imaging
Concept Microscopy, Fluorescence
Concept Protoporphyrins
Concept Recombinant Fusion Proteins
Concept Retrospective Studies
Concept T-Lymphocytes
Concept Thymus Gland
Concept Injury Severity Score
Concept 5'-Nucleotidase
Concept Gene Expression Regulation, Neoplastic
Concept Immunophenotyping
Concept DNA Primers
Concept Sickness Impact Profile
Concept Disease-Free Survival
Concept Coculture Techniques
Concept Epigenesis, Genetic
Concept Microscopy, Electron, Transmission
Concept Chemokine CXCL11
Concept GPI-Linked Proteins
Academic Article Phenotype of CD4+ T cell subsets that develop following mouse facial nerve axotomy.
Academic Article Effects of facial nerve axotomy on Th2- and Th1-associated chemokine expression in the facial motor nucleus of wild-type and presymptomatic mSOD1 mice.
Academic Article Bone marrow mesenchymal stem cells loaded with an oncolytic adenovirus suppress the anti-adenoviral immune response in the cotton rat model.
Academic Article Reduced skin homing by functional Treg in vitiligo.
Academic Article Toll-like receptor 2 and facial motoneuron survival after facial nerve axotomy.
Academic Article The presence of IL-17A and T helper 17 cells in experimental mouse brain tumors and human glioma.
Academic Article Recent developments on immunotherapy for brain cancer.
Academic Article Characterization and immunotherapeutic implications for a novel antibody targeting interleukin (IL)-13 receptor a2.
Academic Article IDO expression in brain tumors increases the recruitment of regulatory T cells and negatively impacts survival.
Academic Article CD4+ T cell-mediated neuroprotection is independent of T cell-derived BDNF in a mouse facial nerve axotomy model.
Academic Article IL-10 within the CNS is necessary for CD4+ T cells to mediate neuroprotection.
Academic Article Thymus-derived rather than tumor-induced regulatory T cells predominate in brain tumors.
Academic Article Short hairpin RNA-mediated fibronectin knockdown delays tumor growth in a mouse glioma model.
Academic Article Exacerbation of facial motoneuron loss after facial nerve axotomy in CCR3-deficient mice.
Academic Article The challenge for gene therapy: innate immune response to adenoviruses.
Academic Article The expression of BST2 in human and experimental mouse brain tumors.
Academic Article Clinical evaluation of an acellular allograft dermal matrix in full-thickness burns.
Academic Article Receptor tyrosine kinase signaling regulates different modes of Groucho-dependent control of Dorsal.
Academic Article Targeting Tregs in Malignant Brain Cancer: Overcoming IDO.
Academic Article Blood-brain barrier permeable gold nanoparticles: an efficient delivery platform for enhanced malignant glioma therapy and imaging.
Academic Article Heme oxygenase-1 protects regulatory T cells from hypoxia-induced cellular stress in an experimental mouse brain tumor model.
Academic Article Nanoparticle-programmed self-destructive neural stem cells for glioblastoma targeting and therapy.
Academic Article Depletion of myeloid-derived suppressor cells during interleukin-12 immunogene therapy does not confer a survival advantage in experimental malignant glioma.
Academic Article Fibrin-binding, peptide amphiphile micelles for targeting glioblastoma.
Academic Article Durable therapeutic efficacy utilizing combinatorial blockade against IDO, CTLA-4, and PD-L1 in mice with brain tumors.
Academic Article Dendritic Cell-Based Vaccines that Utilize Myeloid Rather than Plasmacytoid Cells Offer a Superior Survival Advantage in Malignant Glioma.
Academic Article The role of IDO in brain tumor immunotherapy.
Academic Article The kynurenine to tryptophan ratio as a prognostic tool for glioblastoma patients enrolling in immunotherapy.
Academic Article Molecular Pathways: Targeting IDO1 and Other Tryptophan Dioxygenases for Cancer Immunotherapy.
Academic Article Updates from the Neuro-Oncology Section of the 2015 American Neurological Association Annual Meeting.
Academic Article Functional cloning of a gp100-reactive T-cell receptor from vitiligo patient skin.
Academic Article Tumor relapse prevented by combining adoptive T cell therapy with Salmonella typhimurium.
Academic Article Advanced age negatively impacts survival in an experimental brain tumor model.
Academic Article Improving vaccine efficacy against malignant glioma.
Academic Article CCL2 Produced by the Glioma Microenvironment Is Essential for the Recruitment of Regulatory T Cells and Myeloid-Derived Suppressor Cells.
Academic Article Differential actions of pituitary adenylyl cyclase-activating polypeptide and interferon gamma on Th2- and Th1-associated chemokine expression in cultured murine microglia.
Academic Article Effects of facial nerve axotomy on Th2-associated and Th1-associated chemokine mRNA expression in the facial motor nucleus of wild-type and presymptomatic SOD1 mice.
Academic Article Ménage à trois: Sustained therapeutic anti-tumor immunity requires multiple partners in malignant glioma.
Academic Article The Kynurenine/Tryptophan Ratio and Glioblastoma Patients Treated with Hsppc-96 Vaccine.
Academic Article Immunotherapy for cancer in the central nervous system: Current and future directions.
Academic Article Developmental therapeutics for patients with breast cancer and central nervous system metastasis: current landscape and future perspectives.
Academic Article Non-tumor cell IDO1 predominantly contributes to enzyme activity and response to CTLA-4/PD-L1 inhibition in mouse glioblastoma.
Academic Article Therapeutic Hypothesis Testing With Rodent Brain Tumor Models.
Academic Article The Boosting Potential of Bacteria in Cancer Immunotherapy.
Academic Article A Dendritic Cell-Targeted Adenoviral Vector Facilitates Adaptive Immune Response Against Human Glioma Antigen (CMV-IE) and Prolongs Survival in a Human Glioma Tumor Model.
Academic Article Workshop on challenges, insights, and future directions for mouse and humanized models in cancer immunology and immunotherapy: a report from the associated programs of the 2016 annual meeting for the Society for Immunotherapy of cancer.
Academic Article Lessons learned from rindopepimut treatment in patients with EGFRvIII-expressing glioblastoma.
Academic Article IDO1 Inhibition Synergizes with Radiation and PD-1 Blockade to Durably Increase Survival Against Advanced Glioblastoma.
Academic Article IDO1 in cancer: a Gemini of immune checkpoints.
Academic Article Imaging tryptophan uptake with positron emission tomography in glioblastoma patients treated with indoximod.
Academic Article Indoleamine 2,3-dioxygenase 1 and overall survival of patients diagnosed with esophageal cancer.
Academic Article Challenges and future of biomarker tests in the era of precision oncology: Can we rely on immunohistochemistry (IHC) or fluorescence in situ hybridization (FISH) to select the optimal patients for matched therapy?
Academic Article Infiltrating T Cells Increase IDO1 Expression in Glioblastoma and Contribute to Decreased Patient Survival.
Academic Article Management of glioblastoma in elderly patients.
Academic Article Commentary: preclinical efficacy of immune-checkpoint monotherapy does not recapitulate corresponding biomarkers-based clinical predictions in glioblastoma by Garg et al. (2017).
Academic Article Newly Diagnosed Glioblastoma: A Review on Clinical Management.
Academic Article The Coincidence Between Increasing Age, Immunosuppression, and the Incidence of Patients With Glioblastoma.
Academic Article The interplay among psychological distress, the immune system, and brain tumor patient outcomes.
Academic Article CD73: an emerging checkpoint for cancer immunotherapy.
Academic Article Antibody targeting tumor-derived soluble NKG2D ligand sMIC provides dual co-stimulation of CD8 T cells and enables sMIC+ tumors respond to PD1/PD-L1 blockade therapy.
Academic Article Immunotherapy Against Gliomas: is the Breakthrough Near?
Academic Article Quantification of IDO1 enzyme activity in normal and malignant tissues.
Academic Article Making sense of aches and pains.
Academic Article A retrospective survival analysis of Glioblastoma patients treated with selective serotonin reuptake inhibitors.
Academic Article Antibody targeting tumor-derived soluble NKG2D ligand sMIC reprograms NK cell homeostatic survival and function and enhances melanoma response to PDL1 blockade therapy.
Academic Article Advanced Age Increases Immunosuppression in the Brain and Decreases Immunotherapeutic Efficacy in Subjects with Glioblastoma.
Academic Article Systematic Review of the Kynurenine Pathway and Psychoneurological Symptoms Among Adult Cancer Survivors.
Academic Article Immunosuppressive IDO in Cancer: Mechanisms of Action, Animal Models, and Targeting Strategies.
Academic Article Targeting CD73 to augment cancer immunotherapy.
Academic Article The Impact of Beta Blockers on Survival Outcomes in Patients With Non-small-cell Lung Cancer Treated With Immune Checkpoint Inhibitors.
Academic Article Unique challenges for glioblastoma immunotherapy-discussions across neuro-oncology and non-neuro-oncology experts in cancer immunology. Meeting Report from the 2019 SNO Immuno-Oncology Think Tank.
Academic Article NK cell-based cancer immunotherapy: from basic biology to clinical development.
Academic Article Tryptophan metabolism in brain tumors - IDO and beyond.
Academic Article Tumor-derived NKG2D ligand sMIC reprograms NK cells to an inflammatory phenotype through CBM signalosome activation.
Academic Article Fundholding in northern region: the first year.
Academic Article Information management and technology in England's large acute NHS hospitals. National strategy versus local reality.
Academic Article Tumor Cell IDO Enhances Immune Suppression and Decreases Survival Independent of Tryptophan Metabolism in Glioblastoma.
Academic Article Glioblastoma as an age-related neurological disorder in adults.
Academic Article CD11c+CD163+ Cells and Signal Transducer and Activator of Transcription 3 (STAT3) Expression Are Common in Melanoma Leptomeningeal Disease.
Academic Article Targeting glioblastoma signaling and metabolism with a re-purposed brain-penetrant drug.
Academic Article Early DNA damage detection and cellular autophagy as drivers of stress-adaptive H2S production: A paradox resolved.
Academic Article Mid-life epigenetic age, neuroimaging brain age, and cognitive function: coronary artery risk development in young adults (CARDIA) study.
Academic Article Circadian Regulator CLOCK Drives Immunosuppression in Glioblastoma.
Academic Article A systematic review of pharmacologic treatment efficacy for depression in older patients with cancer.
Academic Article Reshaping the tumor microenvironment with oncolytic viruses, positive regulation of the immune synapse, and blockade of the immunosuppressive oncometabolic circuitry.
Academic Article Next Steps for Immunotherapy in Glioblastoma.
Academic Article Identification and Characterization of a Novel Indoleamine 2,3-Dioxygenase 1 Protein Degrader for Glioblastoma.
Concept Gastrointestinal Microbiome
Concept Antineoplastic Agents, Immunological
Grant The role of IDO and Th17 in an experimental mouse model of glioma
Grant The interaction of IDO and Tregs Leads to Immunosuppression in Glioma
Grant The interaction of IDO and Tregs Leads to Immunosuppression in Glioma
Grant Aging, immunosenescence and glioblastoma
Academic Article Advanced Age in Humans and Mouse Models of Glioblastoma Show Decreased Survival from Extratumoral Influence.
Academic Article CD8+ T cells sustain antitumor response by mediating crosstalk between adenosine A2A receptor and glutathione/GPX4.
Academic Article Lactate dehydrogenase A regulates tumor-macrophage symbiosis to promote glioblastoma progression.
Academic Article LDHA-regulated tumor-macrophage symbiosis promotes glioblastoma progression.
Academic Article Anti-aquaporin-4 immunoglobulin G/anti-myelin oligodendrocyte glycoprotein immunoglobulin G double-positive paraneoplastic neurological syndrome in a patient with triple-negative breast cancer.
Academic Article Age-stratified comorbid and pharmacologic analysis of patients with glioblastoma.
Academic Article Aging amplifies a gut microbiota immunogenic signature linked to heightened inflammation.
Academic Article NKG2C/KLRC2 tumor cell expression enhances immunotherapeutic efficacy against glioblastoma.
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  • Dioxygenase