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Grdina, David
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Item TypeName
Concept Hypoxanthine Phosphoribosyltransferase
Academic Article The inhibition of radiation-induced mutagenesis by the combined effects of selenium and the aminothiol WR-1065.
Academic Article Chemical protection and cell-cycle effects on radiation-induced mutagenesis.
Academic Article Chemopreventive doses of amifostine confer no cytoprotection to tumor nodules growing in the lungs of mice treated with cyclophosphamide.
Academic Article Protection against cis-diamminedichloroplatinum cytotoxicity and mutagenicity in V79 cells by 2-[(aminopropyl)amino]ethanethiol.
Academic Article 2-[(Aminopropyl)amino]ethanethiol (WR1065) is anti-neoplastic and anti-mutagenic when given during 60Co gamma-ray irradiation.
Academic Article The radioprotector WR1065 reduces radiation-induced mutations at the hypoxanthine-guanine phosphoribosyl transferase locus in V79 cells.
Academic Article The radioprotector WR-2721 reduces neutron-induced mutations at the hypoxanthine-guanine phosphoribosyl transferase locus in mouse splenocytes when administered prior to or following irradiation.
Academic Article Induction of hprt mutations in mice after exposure to fission-spectrum neutrons or 60Co gamma rays.
Academic Article Thiol and disulfide metabolites of the radiation protector and potential chemopreventive agent WR-2721 are linked to both its anti-cytotoxic and anti-mutagenic mechanisms of action.
Academic Article Protection by WR1065 and WR151326 against fission-neutron-induced mutations at the HGPRT locus in V79 cells.
Academic Article Protection against radiation-induced mutagenesis at the hprt locus by spermine and N,N"-(dithiodi-2,1-ethanediyl)bis-1,3-propanediamine (WR-33278).
Academic Article Protection against AZT-induced mutagenesis at the HGPRT locus in a human cell line by WR-151326.
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  • Hypoxanthine