| Item Type | Name |
|
Concept
|
Mercaptoethylamines
|
|
Academic Article
|
Reversion of radiosensitivity in azacytidine-treated XRS5 cells does not result in full radioprotection by WR-1065.
|
|
Academic Article
|
Effects of growth media on cell cycle progression in CHO cells exposed to the radioprotector WR-1065.
|
|
Academic Article
|
The inhibition of radiation-induced mutagenesis by the combined effects of selenium and the aminothiol WR-1065.
|
|
Academic Article
|
Chemical protection and cell-cycle effects on radiation-induced mutagenesis.
|
|
Academic Article
|
WR-1065, an active metabolite of the cytoprotector amifostine, affects phosphorylation of topoisomerase II alpha leading to changes in enzyme activity and cell cycle progression in CHO AA8 cells.
|
|
Academic Article
|
Cytoprotection by WR-1065, the active form of amifostine, is independent of p53 status in human malignant glioma cell lines.
|
|
Academic Article
|
Further evidence that the radioprotective aminothiol, WR-1065, catalytically inactivates mammalian topoisomerase II.
|
|
Academic Article
|
Activation of NFkappaB and MnSOD gene expression by free radical scavengers in human microvascular endothelial cells.
|
|
Academic Article
|
Activation of the nuclear transcription factor kappaB (NFkappaB) and differential gene expression in U87 glioma cells after exposure to the cytoprotector amifostine.
|
|
Academic Article
|
Delayed cytoprotection after enhancement of Sod2 (MnSOD) gene expression in SA-NH mouse sarcoma cells exposed to WR-1065, the active metabolite of amifostine.
|
|
Academic Article
|
Differential activation of nuclear transcription factor kappaB, gene expression, and proteins by amifostine's free thiol in human microvascular endothelial and glioma cells.
|
|
Academic Article
|
Inhibition of spontaneous metastases formation by amifostine.
|
|
Academic Article
|
Relationships between cytoprotection and mutation prevention by WR-1065.
|
|
Academic Article
|
Association of WR-1065 with CHO AA8 cells, nuclei, and nucleoids.
|
|
Academic Article
|
Interaction of amifostine and ionizing radiation on transcriptional patterns of apoptotic genes expressed in human microvascular endothelial cells (HMEC).
|
|
Academic Article
|
The effect of chemical radiation protectors on cell cycle progression after gamma or neutron irradiation.
|
|
Academic Article
|
Delayed radioprotection by nuclear transcription factor kappaB -mediated induction of manganese superoxide dismutase in human microvascular endothelial cells after exposure to the free radical scavenger WR1065.
|
|
Academic Article
|
Manganese superoxide dismutase (SOD2)-mediated delayed radioprotection induced by the free thiol form of amifostine and tumor necrosis factor alpha.
|
|
Academic Article
|
Delayed radioprotection by NFkappaB-mediated induction of Sod2 (MnSOD) in SA-NH tumor cells after exposure to clinically used thiol-containing drugs.
|
|
Academic Article
|
WR-1065, the active metabolite of amifostine, mitigates radiation-induced delayed genomic instability.
|
|
Academic Article
|
Protective effects of 2-[(aminopropyl)amino] ethanethiol against bleomycin and nitrogen mustard-induced mutagenicity in V79 cells.
|
|
Academic Article
|
Accumulation of CHO cells in G2 phase following exposure to WR-1065.
|
|
Academic Article
|
Amifostine metabolite WR-1065 disrupts homologous recombination in mammalian cells.
|
|
Academic Article
|
SOD2-mediated adaptive responses induced by low-dose ionizing radiation via TNF signaling and amifostine.
|
|
Academic Article
|
The effect of 2-[(aminopropyl)amino] ethanethiol (WR1065) on radiation-induced DNA damage and repair and cell progression in V79 cells.
|
|
Academic Article
|
Protection against cis-diamminedichloroplatinum cytotoxicity and mutagenicity in V79 cells by 2-[(aminopropyl)amino]ethanethiol.
|
|
Academic Article
|
Inhibition of topoisomerase II alpha activity in CHO K1 cells by 2-[(aminopropyl)amino]ethanethiol (WR-1065).
|
|
Academic Article
|
SOD2-mediated effects induced by WR1065 and low-dose ionizing radiation on micronucleus formation in RKO human colon carcinoma cells.
|
|
Academic Article
|
The effect of 2-[(aminopropyl)amino] ethanethiol on fission-neutron-induced DNA damage and repair.
|
|
Academic Article
|
2-[(Aminopropyl)amino] ethanethiol-mediated reductions in 60Co gamma-ray and fission-spectrum neutron-induced chromosome damage in V79 cells.
|
|
Academic Article
|
Protection against radiation-induced mutagenesis in V79 cells by 2-[(aminopropyl)amino] ethanethiol under conditions of acute hypoxia.
|
|
Academic Article
|
Radioprotectors in treatment therapy to reduce risk in secondary tumor induction.
|
|
Academic Article
|
The effect of 2-[(aminopropyl)amino] ethanethiol (WR-1065) on radiation induced DNA double strand damage and repair in V79 cells.
|
|
Academic Article
|
2-[(Aminopropyl)amino]ethanethiol (WR1065) is anti-neoplastic and anti-mutagenic when given during 60Co gamma-ray irradiation.
|
|
Academic Article
|
The radioprotector WR1065 reduces radiation-induced mutations at the hypoxanthine-guanine phosphoribosyl transferase locus in V79 cells.
|
|
Academic Article
|
Expression of thymidine kinase messenger RNA and a related transcript is modulated by radioprotector WR1065.
|
|
Academic Article
|
Effects of radioprotectors on DNA damage and repair, proteins, and cell-cycle progression.
|
|
Academic Article
|
Cell cycle redistribution of cultured cells after treatment with chemical radiation protectors.
|
|
Academic Article
|
The effects of cycloheximide and WR-1065 on radiation-induced repair processes: a mechanism for chemoprevention.
|
|
Academic Article
|
Amifostine induces antioxidant enzymatic activities in normal tissues and a transplantable tumor that can affect radiation response.
|
|
Academic Article
|
Protection by WR1065 and WR151326 against fission-neutron-induced mutations at the HGPRT locus in V79 cells.
|
|
Academic Article
|
Protection against radiation-induced mutagenesis at the hprt locus by spermine and N,N"-(dithiodi-2,1-ethanediyl)bis-1,3-propanediamine (WR-33278).
|
|
Academic Article
|
Conformational changes in chromatin structure induced by the radioprotective aminothiol, WR 1065.
|
|
Academic Article
|
A manganese superoxide dismutase (SOD2)-mediated adaptive response.
|