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Search Results to Mary Eileen Dolan

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One or more keywords matched the following items that are connected to Dolan, Mary Eileen

Item TypeName
Concept Alkylating Agents
Concept Antineoplastic Agents, Alkylating
Academic Article Effect of O6-benzylguanine analogues on sensitivity of human tumor cells to the cytotoxic effects of alkylating agents.
Academic Article Effect of O6-benzylguanine on alkylating agent-induced toxicity and mutagenicity. In Chinese hamster ovary cells expressing wild-type and mutant O6-alkylguanine-DNA alkyltransferases.
Academic Article O6-alkylguanine-DNA alkyltransferase in cutaneous T-cell lymphoma: implications for treatment with alkylating agents.
Academic Article A phase II trial of oral temozolomide in patients with metastatic renal cell cancer.
Academic Article Effect of O6-benzylguanine on nitrogen mustard-induced toxicity, apoptosis, and mutagenicity in Chinese hamster ovary cells.
Academic Article Temozolomide: realizing the promise and potential.
Academic Article Selective enhancement of ifosfamide-induced toxicity in Chinese hamster ovary cells.
Academic Article Role of O6-alkylguanine-DNA alkyltransferase in protecting against 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU)-induced long-term toxicities.
Academic Article Inactivation of O6-alkylguanine DNA alkyltransferase as a means to enhance chemotherapy.
Academic Article Survival and tumorigenesis in O6-methylguanine DNA methyltransferase-deficient mice following cyclophosphamide exposure.
Academic Article Cancer pharmacoethnicity: ethnic differences in susceptibility to the effects of chemotherapy.
Academic Article Role of O6-methylguanine-DNA methyltransferase in protecting from alkylating agent-induced toxicity and mutations in mice.
Academic Article Role of MGMT in protecting against cyclophosphamide-induced toxicity in cells and animals.
Academic Article Inhibition of nuclear factor-kappaB activity by temozolomide involves O6-methylguanine induced inhibition of p65 DNA binding.
Academic Article Depletion of mammalian O6-alkylguanine-DNA alkyltransferase activity by O6-benzylguanine provides a means to evaluate the role of this protein in protection against carcinogenic and therapeutic alkylating agents.
Academic Article Expression of mammalian O6-alkylguanine-DNA alkyltransferase in a cell line sensitive to alkylating agents.
Academic Article Repair of O-alkylpyrimidines in mammalian cells: a present consensus.
Academic Article Increased killing of prostate, breast, colon, and lung tumor cells by the combination of inactivators of O6-alkylguanine-DNA alkyltransferase and N,N'-bis(2-chloroethyl)-N-nitrosourea.
Academic Article Exposure of HeLa cells to 0(6)-alkylguanines increases sensitivity to the cytotoxic effects of alkylating agents.
Academic Article O6-benzylguanine potentiates the antitumor effect of locally delivered carmustine against an intracranial rat glioma.
Academic Article Phase I pharmacokinetic and pharmacodynamic study of temozolomide in pediatric patients with refractory or recurrent leukemia: a Children's Oncology Group Study.
Academic Article Intraarterial O6-benzylguanine enables the specific therapy of nitrosourea-resistant intracranial human glioma xenografts in athymic rats with 1,3-bis(2-chloroethyl)-1-nitrosourea.
Academic Article Modified guanines representing O(6)-alkylation by the cyclophosphamide metabolites acrolein and chloroacetaldehyde: synthesis, stability, and ab initio studies.
Academic Article Modulation of cyclophosphamide activity by O6-alkylguanine-DNA alkyltransferase.
Academic Article Poly(ADP-ribose) polymerase inhibitor ABT-888 potentiates the cytotoxic activity of temozolomide in leukemia cells: influence of mismatch repair status and O6-methylguanine-DNA methyltransferase activity.
Academic Article Schedule-dependent activity of temozolomide plus CPT-11 against a human central nervous system tumor-derived xenograft.
Academic Article O6-benzylguanine-mediated enhancement of chemotherapy.
Academic Article Multicenter phase II trial of temozolomide in mycosis fungoides/sezary syndrome: correlation with O6-methylguanine-DNA methyltransferase and mismatch repair proteins.
Academic Article Mechanisms of resistance to the toxicity of cyclophosphamide.
Academic Article Poly(ADP-ribose) polymerase-1 inhibition reverses temozolomide resistance in a DNA mismatch repair-deficient malignant glioma xenograft.
Academic Article The role of gene body cytosine modifications in MGMT expression and sensitivity to temozolomide.
Academic Article Integrating cell-based and clinical genome-wide studies to identify genetic variants contributing to treatment failure in neuroblastoma patients.
Academic Article Hydroxylation and N-dechloroethylation of Ifosfamide and deuterated Ifosfamide by the human cytochrome p450s and their commonly occurring polymorphisms.

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  • Alkylating Agents