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Archer, Stephen
One or more keywords matched the following items that are connected to Archer, Stephen
Item TypeName
Concept Hypertension
Concept Hypertension, Portal
Concept Hypertension, Pulmonary
Academic Article Nebulized nitric oxide/nucleophile adduct reduces chronic pulmonary hypertension.
Academic Article Chronic infusion of nitric oxide in experimental pulmonary hypertension: pulmonary pressure-flow analysis.
Academic Article A placebo-controlled trial of prostacyclin in acute respiratory failure in COPD.
Academic Article The somatostatin analog angiopeptin does not reduce chronic hypoxic pulmonary hypertension in rats.
Academic Article Aerosol delivery of diethylenetriamine/nitric oxide, a nitric oxide adduct, causes selective pulmonary vasodilation in perinatal lambs.
Academic Article Pulmonary vasoconstriction, oxygen sensing, and the role of ion channels: Thomas A. Neff lecture.
Academic Article Nitric oxide deficiency in fenfluramine- and dexfenfluramine-induced pulmonary hypertension.
Academic Article Dichloroacetate, a metabolic modulator, prevents and reverses chronic hypoxic pulmonary hypertension in rats: role of increased expression and activity of voltage-gated potassium channels.
Academic Article Primary pulmonary hypertension: a vascular biology and translational research "Work in progress".
Academic Article Case 2. Recurrence of myocardial infarction.
Academic Article Gene transfer and metabolic modulators as new therapies for pulmonary hypertension. Increasing expression and activity of potassium channels in rat and human models.
Academic Article In vivo gene transfer of the O2-sensitive potassium channel Kv1.5 reduces pulmonary hypertension and restores hypoxic pulmonary vasoconstriction in chronically hypoxic rats.
Academic Article Cellular and molecular pathobiology of pulmonary arterial hypertension.
Academic Article Oral sildenafil is an effective and specific pulmonary vasodilator in patients with pulmonary arterial hypertension: comparison with inhaled nitric oxide.
Academic Article Long-term treatment with oral sildenafil is safe and improves functional capacity and hemodynamics in patients with pulmonary arterial hypertension.
Academic Article Canadian Cardiovascular Society and Canadian Thoracic Society position statement on pulmonary arterial hypertension.
Academic Article Acute oxygen-sensing mechanisms.
Academic Article An evidence-based approach to the management of pulmonary arterial hypertension.
Academic Article Canadian Cardiovascular Society and Canadian Thoracic Society position statement on pulmonary arterial hypertension.
Academic Article The NO - K+ channel axis in pulmonary arterial hypertension. Activation by experimental oral therapies.
Academic Article An abnormal mitochondrial-hypoxia inducible factor-1alpha-Kv channel pathway disrupts oxygen sensing and triggers pulmonary arterial hypertension in fawn hooded rats: similarities to human pulmonary arterial hypertension.
Academic Article Overexpression of human bone morphogenetic protein receptor 2 does not ameliorate monocrotaline pulmonary arterial hypertension.
Academic Article The role of k+ channels in determining pulmonary vascular tone, oxygen sensing, cell proliferation, and apoptosis: implications in hypoxic pulmonary vasoconstriction and pulmonary arterial hypertension.
Academic Article Potassium channel diversity in the pulmonary arteries and pulmonary veins: implications for regulation of the pulmonary vasculature in health and during pulmonary hypertension.
Academic Article The nuclear factor of activated T cells in pulmonary arterial hypertension can be therapeutically targeted.
Academic Article ZK 36-374, a stable analog of prostacyclin, prevents acute hypoxic pulmonary hypertension in the dog.
Academic Article Carbon monoxide diffusing capacity and mortality in pulmonary arterial hypertension.
Academic Article Phosphodiesterase type 5 inhibitors for pulmonary arterial hypertension.
Academic Article Survival in pulmonary arterial hypertension: a reappraisal of the NIH risk stratification equation.
Academic Article A dosing/cross-development study of the multikinase inhibitor sorafenib in patients with pulmonary arterial hypertension.
Academic Article Basic science of pulmonary arterial hypertension for clinicians: new concepts and experimental therapies.
Academic Article Diagnosis and management of pulmonary hypertension in systemic sclerosis.
Academic Article Validation of high-resolution echocardiography and magnetic resonance imaging vs. high-fidelity catheterization in experimental pulmonary hypertension.
Academic Article Management of massive and submassive pulmonary embolism, iliofemoral deep vein thrombosis, and chronic thromboembolic pulmonary hypertension: a scientific statement from the American Heart Association.
Academic Article Long-term effects of epoprostenol on the pulmonary vasculature in idiopathic pulmonary arterial hypertension.
Academic Article ACCF/AHA 2009 expert consensus document on pulmonary hypertension a report of the American College of Cardiology Foundation Task Force on Expert Consensus Documents and the American Heart Association developed in collaboration with the American College of Chest Physicians; American Thoracic Society, Inc.; and the Pulmonary Hypertension Association.
Academic Article Antenatal sildenafil treatment attenuates pulmonary hypertension in experimental congenital diaphragmatic hernia.
Academic Article Rodent models of pulmonary hypertension: harmonisation with the world health organisation's categorisation of human PH.
Academic Article Lung ¹8F-fluorodeoxyglucose positron emission tomography for diagnosis and monitoring of pulmonary arterial hypertension.
Academic Article Association of serum creatinine with abnormal hemodynamics and mortality in pulmonary arterial hypertension.
Academic Article Paracrine proliferative signaling by senescent cells in world health organization group 3 pulmonary hypertension: age corrupting youth?
Academic Article Chronic primary and secondary thromboembolic pulmonary hypertension.
Academic Article Gene therapy targeting survivin selectively induces pulmonary vascular apoptosis and reverses pulmonary arterial hypertension.
Academic Article Pulmonary endarterectomy surgery--a technically demanding cure for WHO Group IV Pulmonary Hypertension: requirements for centres of excellence and availability in Canada.
Academic Article Chronic EDRF inhibition and hypoxia: effects on pulmonary circulation and systemic blood pressure.
Academic Article Airway delivery of mesenchymal stem cells prevents arrested alveolar growth in neonatal lung injury in rats.
Academic Article Value of exercise treadmill testing in the risk stratification of patients with pulmonary hypertension.
Academic Article Epigenetic attenuation of mitochondrial superoxide dismutase 2 in pulmonary arterial hypertension: a basis for excessive cell proliferation and a new therapeutic target.
Academic Article Dynamin-related protein 1-mediated mitochondrial mitotic fission permits hyperproliferation of vascular smooth muscle cells and offers a novel therapeutic target in pulmonary hypertension.
Academic Article The WHO classification of pulmonary hypertension: A case-based imaging compendium.
Academic Article Evolving epidemiology of pulmonary arterial hypertension.
Academic Article Comparison of the hemodynamic effects of nitric oxide and endothelium-dependent vasodilators in intact lungs.
Academic Article Increased endothelium-derived NO in hypertensive pulmonary circulation of chronically hypoxic rats.
Academic Article Comparative effects of nisoldipine, nifedipine and bepridil on experimental pulmonary hypertension.
Academic Article Statin therapy, alone or with rapamycin, does not reverse monocrotaline pulmonary arterial hypertension: the rapamcyin-atorvastatin-simvastatin study.
Academic Article Chronic hypoxic pulmonary hypertension. Is thrombin involved?
Academic Article Cellular and molecular basis of pulmonary arterial hypertension.
Academic Article Effect of dietary fish oil on lung lipid profile and hypoxic pulmonary hypertension.
Academic Article Late gadolinium enhancement cardiovascular magnetic resonance predicts clinical worsening in patients with pulmonary hypertension.
Academic Article Anorexic agents aminorex, fenfluramine, and dexfenfluramine inhibit potassium current in rat pulmonary vascular smooth muscle and cause pulmonary vasoconstriction.
Academic Article A role for potassium channels in smooth muscle cells and platelets in the etiology of primary pulmonary hypertension.
Academic Article Pulmonary arterial hypertension: future directions: report of a National Heart, Lung and Blood Institute/Office of Rare Diseases workshop.
Academic Article Hypoxic pulmonary vasoconstriction.
Academic Article Mitochondrial metabolism, redox signaling, and fusion: a mitochondria-ROS-HIF-1alpha-Kv1.5 O2-sensing pathway at the intersection of pulmonary hypertension and cancer.
Academic Article ACCF/AHA 2009 expert consensus document on pulmonary hypertension: a report of the American College of Cardiology Foundation Task Force on Expert Consensus Documents and the American Heart Association: developed in collaboration with the American College of Chest Physicians, American Thoracic Society, Inc., and the Pulmonary Hypertension Association.
Academic Article A proposed mitochondrial-metabolic mechanism for initiation and maintenance of pulmonary arterial hypertension in fawn-hooded rats: the Warburg model of pulmonary arterial hypertension.
Academic Article Epigenetic mechanisms of pulmonary hypertension.
Academic Article PGC1a-mediated mitofusin-2 deficiency in female rats and humans with pulmonary arterial hypertension.
Academic Article QTc prolongation is associated with impaired right ventricular function and predicts mortality in pulmonary hypertension.
Academic Article Metabolism and bioenergetics in the right ventricle and pulmonary vasculature in pulmonary hypertension.
Academic Article FOXO1-mediated upregulation of pyruvate dehydrogenase kinase-4 (PDK4) decreases glucose oxidation and impairs right ventricular function in pulmonary hypertension: therapeutic benefits of dichloroacetate.
Academic Article GRK2-mediated inhibition of adrenergic and dopaminergic signaling in right ventricular hypertrophy: therapeutic implications in pulmonary hypertension.
Academic Article Cardiac glutaminolysis: a maladaptive cancer metabolism pathway in the right ventricle in pulmonary hypertension.
Academic Article Persistence of complex vascular lesions despite prolonged prostacyclin therapy of pulmonary arterial hypertension.
Academic Article Noninvasive cardiac output measurements in patients with pulmonary hypertension.
Academic Article Ischemia-induced Drp1 and Fis1-mediated mitochondrial fission and right ventricular dysfunction in pulmonary hypertension.
Academic Article Increased Drp1-Mediated Mitochondrial Fission Promotes Proliferation and Collagen Production by Right Ventricular Fibroblasts in Experimental Pulmonary Arterial Hypertension.
Academic Article A pro-con debate: current controversies in PAH pathogenesis at the American Thoracic Society International Conference in 2017.
Academic Article Acquired Mitochondrial Abnormalities, Including Epigenetic Inhibition of Superoxide Dismutase 2, in Pulmonary Hypertension and Cancer: Therapeutic Implications.
Academic Article Pulmonary pulse wave transit time is associated with right ventricular-pulmonary artery coupling in pulmonary arterial hypertension.
Academic Article Soluble guanylate cyclase: a new therapeutic target for pulmonary arterial hypertension and chronic thromboembolic pulmonary hypertension.
Academic Article Survival in pulmonary hypertension due to chronic lung disease: Influence of low diffusion capacity of the lungs for carbon monoxide.
Academic Article Pulmonary arterial hypertension: pathogenesis and clinical management.
Academic Article Transcriptomic Signature of Right Ventricular Failure in Experimental Pulmonary Arterial Hypertension: Deep Sequencing Demonstrates Mitochondrial, Fibrotic, Inflammatory and Angiogenic Abnormalities.
Academic Article Trends and Outcomes of Pulmonary Arterial Hypertension-Related Hospitalizations in the United States: Analysis of the Nationwide Inpatient Sample Database From 2001 Through 2012.
Academic Article Disproportionate Right Ventricular Dysfunction and Poor Survival in Group 3 Pulmonary Hypertension.
Academic Article Interleukin-6 is independently associated with right ventricular function in pulmonary arterial hypertension.
Academic Article Riociguat for pulmonary hypertension--a glass half full.
Academic Article Epigenetic Dysregulation of the Dynamin-Related Protein 1 Binding Partners MiD49 and MiD51 Increases Mitotic Mitochondrial Fission and Promotes Pulmonary Arterial Hypertension: Mechanistic and Therapeutic Implications.
Academic Article Rodent models of group 1 pulmonary hypertension.
Academic Article Critical Genomic Networks and Vasoreactive Variants in Idiopathic Pulmonary Arterial Hypertension.
Academic Article Emerging concepts in the molecular basis of pulmonary arterial hypertension: part I: metabolic plasticity and mitochondrial dynamics in the pulmonary circulation and right ventricle in pulmonary arterial hypertension.
Academic Article Anticipated classes of new medications and molecular targets for pulmonary arterial hypertension.
Academic Article An official American Thoracic Society Statement: pulmonary hypertension phenotypes.
Academic Article The right ventricle in pulmonary arterial hypertension: disorders of metabolism, angiogenesis and adrenergic signaling in right ventricular failure.
Academic Article Executive Summary of the American Heart Association and American Thoracic Society Joint Guidelines for Pediatric Pulmonary Hypertension.
Academic Article Colchicine Depolymerizes Microtubules, Increases Junctophilin-2, and Improves Right Ventricular Function in Experimental Pulmonary Arterial Hypertension.
Academic Article [Relevant issues in the pathology and pathobiology of pulmonary hypertension].
Academic Article MicroRNA-138 and MicroRNA-25 Down-regulate Mitochondrial Calcium Uniporter, Causing the Pulmonary Arterial Hypertension Cancer Phenotype.
Academic Article Right ventricular adaptation and failure in pulmonary arterial hypertension.
Academic Article Pediatric Pulmonary Hypertension: Guidelines From the American Heart Association and American Thoracic Society.
Academic Article Mitochondrial dynamics in pulmonary arterial hypertension.
Academic Article Standards and Methodological Rigor in Pulmonary Arterial Hypertension Preclinical and Translational Research.
Academic Article Models and Molecular Mechanisms of World Health Organization Group 2 to 4 Pulmonary Hypertension.
Academic Article Peripheral blood signature of vasodilator-responsive pulmonary arterial hypertension.
Academic Article Pyruvate Kinase and Warburg Metabolism in Pulmonary Arterial Hypertension: Uncoupled Glycolysis and the Cancer-Like Phenotype of Pulmonary Arterial Hypertension.
Academic Article Pulmonary hypertension begets pulmonary hypertension: mutually reinforcing roles for haemodynamics, inflammation, and cancer-like phenotypes.
Academic Article Relevant issues in the pathology and pathobiology of pulmonary hypertension.
Academic Article Increasing Incidence and Prevalence of World Health Organization Groups 1 to 4 Pulmonary Hypertension: A Population-Based Cohort Study in Ontario, Canada.
Academic Article A Step Closer to Understanding How Riociguat Results in Remodelling of the Right Ventricle in Chronic Thromboembolic Pulmonary Hypertension.
Academic Article Genetic determinants of risk in pulmonary arterial hypertension: international genome-wide association studies and meta-analysis.
Academic Article Repurposing Medications for Treatment of Pulmonary Arterial Hypertension: What's Old Is New Again.
Academic Article Clinical Determinants and Prognostic Implications of Right Ventricular Dysfunction in Pulmonary Hypertension Caused by Chronic Lung Disease.
Academic Article Pathophysiology, incidence, management, and consequences of cardiac arrhythmia in pulmonary arterial hypertension and chronic thromboembolic pulmonary hypertension.
Academic Article Biventricular Increases in Mitochondrial Fission Mediator (MiD51) and Proglycolytic Pyruvate Kinase (PKM2) Isoform in Experimental Group 2 Pulmonary Hypertension-Novel Mitochondrial Abnormalities.
Academic Article Left Atrial Stenosis Induced Pulmonary Venous Arterialization and Group 2 Pulmonary Hypertension in Rat.
Academic Article Metabolic Syndrome Exacerbates Pulmonary Hypertension due to Left Heart Disease.
Academic Article Hypochloremia Is a Noninvasive Predictor of Mortality in Pulmonary Arterial Hypertension.
Academic Article Novel Mutations and Decreased Expression of the Epigenetic Regulator TET2 in Pulmonary Arterial Hypertension.
Academic Article Mitochondria in the Pulmonary Vasculature in Health and Disease: Oxygen-Sensing, Metabolism, and Dynamics.
Academic Article Epigenetic Metabolic Reprogramming of Right Ventricular Fibroblasts in Pulmonary Arterial Hypertension: A Pyruvate Dehydrogenase Kinase-Dependent Shift in Mitochondrial Metabolism Promotes Right Ventricular Fibrosis.
Academic Article Supra-coronary aortic banding improves right ventricular function in experimental pulmonary arterial hypertension in rats by increasing systolic right coronary artery perfusion.
Academic Article Differentiating COVID-19 Pneumonia From Acute Respiratory Distress Syndrome and High Altitude Pulmonary Edema: Therapeutic Implications.
Academic Article Identification of Long Noncoding RNA H19 as a New Biomarker and Therapeutic Target in Right Ventricular Failure in Pulmonary Arterial Hypertension.
Academic Article Endothelial BMPR2 Loss Drives a Proliferative Response to BMP (Bone Morphogenetic Protein) 9 via Prolonged Canonical Signaling.
Academic Article Evaluation of the Impact of an Echocardiographic Diagnosis of Pulmonary Hypertension on Patient Outcomes.
Academic Article Excess Protein O-GlcNAcylation Links Metabolic Derangements to Right Ventricular Dysfunction in Pulmonary Arterial Hypertension.
Academic Article Oxygen sensing, mitochondrial biology and experimental therapeutics for pulmonary hypertension and cancer.
Academic Article Scientist on the Spot: Exploring the cause and cure for pulmonary arterial hypertension.
Academic Article Hemodynamic Characteristics and Outcomes of Pulmonary Hypertension in Patients Undergoing Tricuspid Valve Repair or Replacement.
Academic Article Left Main Coronary Artery Compression in Pulmonary Arterial Hypertension: Percutaneous Treatment to Improve Symptoms.
Academic Article Corrigendum to: Scientist on the spot: Exploring the cause and cure for pulmonary arterial hypertension.
Academic Article Carvedilol for Treatment of Right Ventricular Dysfunction in Pulmonary Arterial Hypertension.
Academic Article PINK1-induced phosphorylation of mitofusin 2 at serine 442 causes its proteasomal degradation and promotes cell proliferation in lung cancer and pulmonary arterial hypertension.
Academic Article Diagnosis and Treatment of Right Heart Failure in Pulmonary Vascular Diseases: A National Heart, Lung, and Blood Institute Workshop.
Academic Article Inflammatory Glycoprotein 130 Signaling Links Changes in Microtubules and Junctophilin-2 to Altered Mitochondrial Metabolism and Right Ventricular Contractility.
Academic Article Inhibiting pyruvate kinase muscle isoform 2 regresses group 2 pulmonary hypertension induced by supra-coronary aortic banding.
Academic Article Using health administrative data to identify patients with pulmonary hypertension: A single center, proof of concept validation study in Ontario, Canada.
Academic Article Macrophage-NLRP3 Activation Promotes Right Ventricle Failure in Pulmonary Arterial Hypertension.
Academic Article An integrated proteomic and transcriptomic signature of the failing right ventricle in monocrotaline induced pulmonary arterial hypertension in male rats.
Academic Article Acquired disorders of mitochondrial metabolism and dynamics in pulmonary arterial hypertension.
Academic Article Effect of Chronic Digoxin Use on Mortality and Heart Failure Hospitalization in Pulmonary Arterial Hypertension.
Concept Familial Primary Pulmonary Hypertension
Grant Impaired mitochondrial fusion in pulmonary arterial hypertension
Grant EDRF IN NORMAL AND HYPERTENSIVE PULMONARY VASCULATURE
Grant The Role of DRP-1 and Mitochondrial Fission in Pulmonary Arterial Hypertension
Academic Article The Role of Mitochondrial Dynamics and Mitotic Fission in Regulating the Cell Cycle in Cancer and Pulmonary Arterial Hypertension: Implications for Dynamin-Related Protein 1 and Mitofusin2 in Hyperproliferative Diseases.
Academic Article The Role of Clonal Hematopoiesis of Indeterminant Potential and DNA (Cytosine-5)-Methyltransferase Dysregulation in Pulmonary Arterial Hypertension and Other Cardiovascular Diseases.
Academic Article Complete Revascularization of the Pulmonary Circulation in Chronic Thromboembolic Pulmonary Hypertension: Value of Addressing Chronic Total Occlusions.
Academic Article Efficacy of Drpitor1a, a Dynamin-Related Protein 1 inhibitor, in Pulmonary Arterial Hypertension.
Academic Article Pulmonary hypertension.
Academic Article Germline and Somatic Mutations in DNA Methyltransferase 3A (DNMT3A) Predispose to Pulmonary Arterial Hypertension (PAH) in Humans and Mice: Implications for Associated PAH.
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