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Hanck, Dorothy
One or more keywords matched the following items that are connected to Hanck, Dorothy
Item TypeName
Concept Mutagenesis, Site-Directed
Academic Article Leucine 18, a hydrophobic residue essential for high affinity binding of anthopleurin B to the voltage-sensitive sodium channel.
Academic Article Role for Pro-13 in directing high-affinity binding of anthopleurin B to the voltage-sensitive sodium channel.
Academic Article A specific interaction between the cardiac sodium channel and site-3 toxin anthopleurin B.
Academic Article The Na channel voltage sensor associated with inactivation is localized to the external charged residues of domain IV, S4.
Academic Article The role of the putative inactivation lid in sodium channel gating current immobilization.
Academic Article Arg-14 loop of site 3 anemone toxins: effects of glycine replacement on toxin affinity.
Academic Article Role of Asn-16 and Ser-19 in anthopleurin B binding. Implications for the electrostatic nature of Na(V) site 3.
Academic Article Charge immobilization of the voltage sensor in domain IV is independent of sodium current inactivation.
Academic Article Molecular action of lidocaine on the voltage sensors of sodium channels.
Academic Article State-dependent mibefradil block of Na+ channels.
Academic Article Charge at the lidocaine binding site residue Phe-1759 affects permeation in human cardiac voltage-gated sodium channels.
Academic Article The N terminus of connexin37 contains an alpha-helix that is required for channel function.
Academic Article Verapamil block of T-type calcium channels.
Academic Article Sodium channel molecular conformations and antiarrhythmic drug affinity.
Academic Article The outermost lysine in the S4 of domain III contributes little to the gating charge in sodium channels.
Grant Cardiac Channels: Targets of Drugs that Affect Kinetics
Grant STRUCTURAL BASES OF T-TYPE CALCIUM CHANNEL FUNCTION
Grant Drug therapy targeted to the voltage-gated sodium channel
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  • Mutagenesis